- Soft tissue tumor case studies
- Bone Tumor Diagnosis and Treatments
- Vascular Tumors and Angiosarcomas
- Sarcoma Diagnosis and Treatment
- Immune cells in cancer
- Ferroptosis and cancer prognosis
- Oral and Maxillofacial Pathology
- Neurofibromatosis and Schwannoma Cases
- Extracellular vesicles in disease
- Cancer Genomics and Diagnostics
- Salivary Gland Tumors Diagnosis and Treatment
- Healthcare Systems and Practices
- Cancer Immunotherapy and Biomarkers
- Health, Medicine and Society
- Glioma Diagnosis and Treatment
- Vascular Malformations and Hemangiomas
Centre Hospitalier Universitaire Amiens-Picardie
2019-2024
Université de Picardie Jules Verne
2020
Background: Hemostatic complications, ranging from thromboembolism to bleeding, are a significant source of morbidity and mortality in cancer patients. The tumor coagulome represents the multiple genes proteins that locally contribute equilibrium between coagulation fibrinolysis. We aimed study Oral Squamous Cell Carcinoma (OSCC) examine its link microenvironment (TME). Methods: used data bulk DNA/RNA-seq (The Cancer Genome Atlas), single-cell RNA-seq OSCC cells culture. Results: Among all...
The tumor microenvironment is an important determinant of glioblastoma (GBM) progression and response to treatment. How oncogenic signaling in GBM cells modulates the composition its activation unclear. We aimed explore potential local immunoregulatory function ERK1/2 GBM. Using proteomic transcriptomic data (RNA seq) available for tumors from Cancer Genome Atlas (TCGA), we show that with high levels phosphorylated have increased infiltration tumor-associated macrophages (TAM) a...
Background: Intracranial solitary fibrous tumour (iSFT) is an exceptional mesenchymal with high recurrence rates. We aimed to analyse the clinical outcomes of newly diagnosed and recurrent iSFTs. Methods: carried out a French retrospective multicentre (n = 16) study histologically proven iSFT cases. Univariate multivariate Cox models were used estimate prognosis value age, location, size, WHO grade, surgical extent on overall survival (OS), progression-free (PFS), local recurrence-free...