A5015913924- RNA modifications and cancer
- Head and Neck Cancer Studies
- Ferroptosis and cancer prognosis
- Cancer-related Molecular Pathways
- Molecular Biology Techniques and Applications
- Cancer Genomics and Diagnostics
- Lung Cancer Treatments and Mutations
- Radiopharmaceutical Chemistry and Applications
- Immune cells in cancer
- Epigenetics and DNA Methylation
- Oral Health Pathology and Treatment
- Nonmelanoma Skin Cancer Studies
- Glioma Diagnosis and Treatment
- Lung Cancer Research Studies
- Cancer Mechanisms and Therapy
- Hedgehog Signaling Pathway Studies
- Cancer Immunotherapy and Biomarkers
Inserm
2024
Sorbonne Université
2024
Centre de Recherche des Cordeliers
2024
Université Paris Cité
2024
Université de Picardie Jules Verne
2019-2021
Chirurgie et extrémité céphalique, caractérisation morphologique et fonctionnelle
2020
The tumor microenvironment is an important determinant of glioblastoma (GBM) progression and response to treatment. How oncogenic signaling in GBM cells modulates the composition its activation unclear. We aimed explore potential local immunoregulatory function ERK1/2 GBM. Using proteomic transcriptomic data (RNA seq) available for tumors from Cancer Genome Atlas (TCGA), we show that with high levels phosphorylated have increased infiltration tumor-associated macrophages (TAM) a...
The immune checkpoint molecule PD-L1 (CD274) is a crucial regulator of the tumor response. Its expression has been reported in therapeutic context Head and Neck Squamous Cell Carcinoma (HNSCC), but it remains unclear how therapeutically approved molecules regulate HNSCC cells. Three cell lines (BICR6, PE/CA-PJ34 PE/CA-PJ41) were used to analyze by immunoblotting, immunofluorescence QPCR. Freely-available single RNAseq data from also used. 5-Fluorouracil (5-FU) increased with high efficacy...
Patients with EGFR-mutated non-small cell lung cancer (NSCLC) benefit from treatment tyrosine kinase inhibitors (TKI) targeting EGFR. Despite improvements in patient care, especially the 3rd generation TKI osimertinib, disease relapse is observed all patients. Among various processes involved resistance, epithelial-to-mesenchymal transition (EMT) far being fully characterized. We hypothesized that cellular prion protein PrP
The article "ASO Visual Abstract: Contribution of Genomics.