- Bone fractures and treatments
- Anesthesia and Pain Management
- Spine and Intervertebral Disc Pathology
- Cardiac, Anesthesia and Surgical Outcomes
- Orthopaedic implants and arthroplasty
- Pain Management and Opioid Use
- Health and Medical Studies
- Musculoskeletal pain and rehabilitation
- Medical Practices and Rehabilitation
- Orthopedic Infections and Treatments
- Orthopedic Surgery and Rehabilitation
- Spondyloarthritis Studies and Treatments
- Hip and Femur Fractures
- Cardiac Health and Mental Health
- COVID-19 Clinical Research Studies
- Scoliosis diagnosis and treatment
- Pain Mechanisms and Treatments
- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
- Sexual Differentiation and Disorders
- Medical and Health Sciences Research
- Hemodynamic Monitoring and Therapy
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Medical Imaging and Analysis
- Cardiovascular Function and Risk Factors
University of St. Gallen
2024-2025
Kantonsspital St. Gallen
2024-2025
University Hospital of Bern
2021-2024
University of Bern
2024
Queensland University of Technology
2013-2018
Saarland University
2012-2015
Johannes Gutenberg University Mainz
2011
Accurate prediction of intensive care unit (ICU) admission and length stay (LOS) after major surgery is essential for optimizing patient outcomes healthcare resources. Factors such as age, BMI, comorbidities, perioperative complications significantly influence ICU admissions LOS. Machine learning methods have been increasingly utilized to predict these outcomes, but their clinical utility beyond traditional metrics remains underexplored. This study examined a sub-cohort 6043 patients who...
Abstract Recent trends in first-line transsphenoidal surgery (TSS) for prolactinoma patients aim to reduce long-term dependence on dopamine agonists (DA). Key factors linked poor surgical outcomes include cavernous sinus invasiveness and high baseline serum prolactin (PRL) levels. Defining simple PRL threshold values indicate inform treatment strategy is crucial. In this retrospective cohort study of 149 treated with or agonist (DA) therapy, we evaluated preoperative levels invasion as...
Indoleamine 2,3-deoxygenase (IDO) plays an important role in the catabolism of amino acid tryptophan. Tryptophan and its metabolites are key immune modulators. Increased IDO activity has been observed various diseases is associated with worse clinical outcomes. However, comprehensive research regarding cardiac surgery remains limited. Therefore, we aimed to investigate perioperative changes pathway metabolites, along their impact on outcomes adult patients undergoing surgery. As...
Abstract Purpose Erectile dysfunction (ED) is frequently underreported in men suffering from prolactinomas and can be challenging to manage. Both dopamine agonists (DAs) transsphenoidal surgery (TSS) correct hyperprolactinemia restore gonadal function. However, there scarce data regarding their effectiveness correcting ED over the long term. Methods This study a retrospective single-center comparative cohort analyzing diagnosed with prolactinomas, both without confirmed erectile at...
Murine osteotomy and fracture models have become the standard to study molecular mechanisms of bone healing. Because there is little information whether healing osteotomies differs from that fractures, we herein studied in mice femur compared fractures. Twenty CD-1 underwent a standardized open osteotomy. Another 20 received fracture. Stabilization was performed by an intramedullary screw. Bone micro-CT, biomechanical, histomorphometric protein expression analyses. Osteotomies revealed...
Ketone bodies (KBs) are energy-efficient substrates utilized by the heart depending on its metabolic demand and substrate availability. Levels of circulating KBs have been shown to be elevated in acute chronic cardiovascular disease associated with severity patients failure functional outcome after myocardial infarction. To investigate whether this pattern similarly applies undergoing cardiac surgery involving cardiopulmonary bypass (CPB), we analysed prospectively collected pre-...
Im Rahmen der Diskussionen zum Erstzugang in Physiotherapie Deutschland kommen zunehmend größere Herausforderungen auf alle Physiotherapeuten zu. Zuge dessen von Physio-/Manualtherapeuten erwartete Kompetenzen sind das Erkennen Risikofaktoren für die Behandlung.
Unabhängig von politischen und rechtlichen Entwicklungen ist der Direktzugang Patienten zum Physiotherapeuten neben Professionalisierung Akademisierung des Berufsstandes ein aktuelles Thema. Dabei spielen die Einstellung deutscher Direct Access (DA) genauso wie diese beeinflussenden Faktoren eine Rolle.
Survivors of Coronavirus disease 2019 frequently experience an array symptoms following discharge from hospital. The most common after severe COVID-19 and hospitalization are fatigue, breathlessness joint pain. (C. A. et al. JAMA. 2020; 324(6):603-605. S. W. BMJ. 2021; 372:n136) However, medium long-term experienced by patients with mild or moderate remain unclear. We retrospectively analyzed a descriptive case series 46 monitored in outpatient pneumologist's clinic at three timepoints (one,...