A5013197252- Congenital Heart Disease Studies
- Aortic Disease and Treatment Approaches
- Cardiac Valve Diseases and Treatments
- Pulmonary Hypertension Research and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiovascular Effects of Exercise
- Cardiomyopathy and Myosin Studies
- Cardiac Arrhythmias and Treatments
- Vascular anomalies and interventions
- Cardiac pacing and defibrillation studies
- Coronary Artery Anomalies
- Cardiovascular and Diving-Related Complications
- Connective tissue disorders research
- Viral Infections and Immunology Research
- Cardiovascular Issues in Pregnancy
- Cardiovascular Function and Risk Factors
- Congenital Diaphragmatic Hernia Studies
- Infective Endocarditis Diagnosis and Management
- Tracheal and airway disorders
- Congenital heart defects research
- Aortic aneurysm repair treatments
- Ultrasound in Clinical Applications
- Neonatal Respiratory Health Research
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Disease and Adiposity
Universitat Autònoma de Barcelona
2015-2024
Vall d'Hebron Hospital Universitari
2009-2024
Hebron University
2022-2024
Hospital de Sant Pau
2023
Centro de Investigación en Red en Enfermedades Cardiovasculares
2021
Sociedad Española de Cardiología
2019-2020
Hospital Materno-Infantil
2017
Ideon Innovation (Sweden)
2015
Mayo Clinic in Arizona
2013-2015
Mayo Clinic in Florida
2014
Abstract Objective Pulmonary hypertension (PH) worsens the prognosis of bronchopulmonary dysplasia (BPD). The following items have not been fully established for PH in BPD: clinical characterization, incidence cardiovascular anomalies (CVAs), response to treatment, and outcome. Study Design A review records, computed tomography (CT) images catheterization data 36 patients with PH‐BPD referred our Unit (March 2006 December 2011) was performed. Twenty‐nine without major congenital heart...
Rationale: There is a lack of knowledge regarding the epidemiology, clinical characterization, and survival in pediatric pulmonary hypertension.Objectives: To describe outcomes, risk factors for mortality hypertension Spain.Methods: We analyzed data from Spanish Registry Pediatric Pulmonary Hypertension. From January 2009 to June 2012, total 225 patients diagnosed with 1998 or after were collected 21 referral nonreferral centers. included all Nice etiologies, estimated incidence prevalence...
Background— Most patients with repaired tetralogy of Fallot require pulmonary valve replacement (PVR), but the evaluation for and management ventricular arrhythmia remain unclear. This study is aimed at clarifying optimal approach to this potentially life-threatening issue time PVR. Methods Results— A retrospective analysis was performed on 205 undergoing PVR our institution between 1988 2010. Median age 32.9 (range, 25.6) years. Previous tachycardia occurred in 16 (8%) 37 (16%) had left...
Biventricular obstruction in hypertrophic cardiomyopathy (HCM) is uncommon, and some clinicians believe that, when symptoms are refractory to medical treatment, this severe form of HCM best treated by transplantation. We describe our conventional surgical approach outcomes treat biventricular HCM. From 1993 2013, we 11 symptomatic patients with outflow obstruction. Relief left ventricular (LV) was obtained performing a transaortic extended septal myectomy and/or apical ventriculotomy. Right...
Abstract Bicuspid aortic valve (BAV) is the most common congenital heart malformation in adults but can also cause childhood-onset complications. In multicenter study, we found that who experience significant complications of BAV disease before age 30 are distinguished from majority cases manifest after 50 by a relatively severe clinical course, with higher rates surgical interventions, more frequent second and greater burden malformations. These observations highlight need for prompt...
Bicuspid aortic valve (BAV), the most common congenital heart defect, is a major cause of disease requiring interventions and thoracic aneurysms predisposing to acute dissections. The spectrum BAV ranges from early onset complications (EBAV) sporadic late disease. Rare genomic copy number variants (CNVs) have previously been implicated in development aneurysms. We determined frequency gene content rare CNVs EBAV probands (n = 272) using genome-wide SNP microarray analysis three complementary...
Heritable thoracic aortic diseases (HTAD), typically entailing complications, can be caused by pathogenic variants or likely (PV/LPVs) in several genes, including fibrillin1 (FBN1), Actin Alpha2 (ACTA2) and genes encoding components of the transforming growth factor (TGF)-β signaling pathway. In addition to non-aortic cardiac disease such as impaired myocardial function and/or arrhythmia have been increasingly reported, mainly Marfan syndrome with underlying FBN1 PV/LPVs are acknowledged...
To compare the safety and effectiveness of video-assisted thoracic surgery (VATS) versus conventional median sternotomy (open) in repair secundum atrial septal defect (ASD) or patent foramen ovale (PFO).Among 415 consecutive patients undergoing open VATS ASD/PFO closure between 1993 October 2012, 153 were compared using 2:1 frequency matching (n=102 vs 51 VATS). Matching variables include age, gender, body surface area, past medical history neurologic events, need patch closure. Median age...
Many antiviral agents, such as hydroxychloroquine, have been used to treat COVID-19, without being broadly accepted. QTc prolongation is a worrisome adverse effect, scarcely studied in pediatrics.Paediatric patients affected from COVID-19 who received antivirals were matched (1:2) with controls not infected nor exposed. Electrocardiograms prospectively analyzed at baseline, during the first 72 h of treatment and after h.Eleven (22.9%) out 48 admitted due (March-July 2020) therapy. All had...
Ascending aorta diameters have important clinical value in the diagnosis, follow-up, and surgical indication of many aortic diseases. However, there is no uniformity among experts regarding ascending diameter quantification by echocardiography. The aim this study was to compare maximum root determined diastolic leading edge (DLE) systolic inner (SIE) conventions adult pediatric patients with inherited cardiovascular Transthoracic echocardiograms were performed 328 consecutive (260 adults 68...
Flecainide is a class IC antiarrhythmic indicated for ventricular and supraventricular arrhythmias in pediatric patients without structural heart disease. has narrow therapeutic window proarrhythmic effect even doses could lead to life-threatening intoxication. Dosage errors, accidental intakes, drug or food interactions, especially with dairy products, can be the cause of We report three consecutive cases flecainide intoxication children tachycardia (SVT) our hospital from 2017 2019. Two...
Abstract Bicuspid aortic valve (BAV), the most common congenital heart defect, is a major cause of disease requiring interventions and thoracic aneurysms predisposing to acute dissections. The spectrum BAV ranges from early onset complications (EBAV) sporadic late disease. Rare genomic copy number variants (CNVs) have previously been implicated in development aneurysms. We determined frequency gene content rare CNVs EBAV probands (n = 272) using genome-wide SNP microarray analysis three...