A5009803153- Electromagnetic Fields and Biological Effects
- Carcinogens and Genotoxicity Assessment
- DNA Repair Mechanisms
- Polyamine Metabolism and Applications
- Mitochondrial Function and Pathology
- Photoreceptor and optogenetics research
- Wireless Body Area Networks
- Media Influence and Health
- Electron Spin Resonance Studies
- Nitric Oxide and Endothelin Effects
- Cardiac electrophysiology and arrhythmias
- Behavioral Health and Interventions
- Forest Ecology and Biodiversity Studies
- Amino Acid Enzymes and Metabolism
- Magnetic and Electromagnetic Effects
- Child Nutrition and Feeding Issues
- Eating Disorders and Behaviors
- Effects of Radiation Exposure
- Microtubule and mitosis dynamics
- Biofield Effects and Biophysics
- Wireless Power Transfer Systems
University of Eastern Finland
2004-2021
Human SH-SY5Y neuroblastoma and mouse L929 fibroblast cells were exposed to 872 MHz radiofrequency (RF) radiation using continuous waves (CW) or a modulated signal similar that emitted by GSM mobile phones at specific absorption rate (SAR) of 5 W/kg in isothermal conditions. To investigate possible combined effects with other agents, menadione was used induce reactive oxygen species, tert-butylhydroperoxide (t-BOOH) lipid peroxidation. After 1 24 h exposure, reduced cellular glutathione...
Background Extremely low frequency (ELF) magnetic fields (MF) are generated by power lines and various electric appliances. They have been classified as possibly carcinogenic the International Agency for Research on Cancer, but a mechanistic explanation effects is lacking. A previous study in our laboratory showed that pre-exposure to ELF MF altered cancer-relevant cellular responses (cell cycle arrest, apoptosis) menadione-induced DNA damage, it did not include endpoints measuring actual...
In our previous studies, exposure to extremely low frequency (ELF) magnetic fields (MF) altered responses DNA damage caused by menadione. The aim of this study was evaluate possible ELF MF induced changes in proteins involved and cell cycle distribution.Based on the protocol included pre-exposure human SH-SY5Y neuroblastoma cells a 50 Hz, 100 μT for 24 h prior 3-h menadione treatment. As are relatively fast processes, 1-h treatment also experiments. concentrations used were 1, 10, 15, 20, 25...
The effects of radiofrequency (RF) radiation on cellular ornithine decarboxylase (ODC) activity were studied in fibroblasts, two neural cell lines and primary astrocytes. Several exposure times levels used, the fields either unmodulated or modulated according to characteristics Global System for Mobile (GSM) communications.Murine L929 rat C6 glioblastoma cells, human SH-SY5Y neuroblastoma astrocytes exposed RF at 872 MHz a waveguide chamber equipped with water cooling. Cells 2, 8, 24 hours...
We tested the hypothesis that effects of 50 Hz magnetic fields (MFs) on superoxide levels and genotoxicity depend presence blue light.Human SH-SY5Y neuroblastoma cells were exposed to a Hz, 100 μT MF with or without non-phototoxic level light for 24 h. also studied whether these treatments alter responses menadione, an agent induces mitochondrial (O2• -) production DNA damage. Micronuclei, proliferation, viability, cytosolic O2• - assessed.MF (without light) increased suppressed this effect....
Abstract A replication study with some extensions was made to confirm enhancement of ornithine decarboxylase (ODC) activity in murine L929 fibroblasts after radiofrequency (RF) field exposure reported earlier studies. cells purchased from two cell banks were exposed for 2, 8, or 24 h continuous wave DAMPS (burst modulated at 50 Hz, 33% duty cycle) signals specific absorption rate (SAR) levels 2.5 6.0 W/kg. Exposures carried out Crawford and waveguide chambers, frequencies 835 872 MHz,...
Purpose: The aim of this study was to test the hypothesis that variations in physiological state cells explain inconsistent results from vitro studies on biological effects radiofrequency (RF) radiation.Materials and methods: Murine L929 fibroblasts stimulated with fresh medium, stressed serum deprivation or not subjected stimulation stress were exposed a waveguide exposure chamber 872 MHz continuous wave pulse modulated (217 pulses per second) RF radiation at specific absorption rate 5...
Abstract Ionizing radiation has been shown to cause induced genomic instability (IGI), which is defined as a persistently increased rate of damage in the progeny exposed cells. In this study, IGI was investigated by exposing human SH-SY5Y neuroblastoma cells hydroxyurea and zeocin, two chemicals mimicking different DNA-damaging effects ionizing radiation. The aim explore whether associated with persistent mitochondrial dysfunction. Changes function were assessed analyzing superoxide...
Tutkimuksen tarkoituksena oli kuvata 16–20-vuotiaiden suomalaisnuorten aurinkosuojautumista. Tutkimus liittyy valtakunnalliseen nuorten aurinkosuojautumiskampanjaan, jota ovat yhteistyössä toteuttaneet Säteilyturvakeskus, Ilmatieteen laitos, Syöpäjärjestöt sekä Itä-Suomen yliopisto. Tutkimusaineisto muodostuu yhdentoista nuoren yksilöhaastatteluista (n=11) ja se kerättiin kaksivaiheisesti; aurinkosuojautumiskampanjan suunnitteluvaiheessa vuonna 2020 kampanjan jatkuessa joulukuun 2021...