A5008601456- Nosocomial Infections in ICU
- Pneumonia and Respiratory Infections
- Ultrasound in Clinical Applications
- Retinal Diseases and Treatments
- Emergency and Acute Care Studies
- Pleural and Pulmonary Diseases
- Retinal Development and Disorders
- Cerebrovascular and genetic disorders
- Pneumothorax, Barotrauma, Emphysema
Intermountain Healthcare
2024
University of Utah
2021
Significance The chromosome 10q26 locus is the genetic region most strongly associated with elevated risk of age-related macular degeneration (AMD), but underlying defects initiating disease are unresolved. Using human-derived eye tissues, we demonstrate that mRNA encoding serine protease, HTRA1, reduced in retinal pigment epithelium (RPE) donors risk-associated variants disrupt a cis-regulatory element within locus. Consequentially, there diminished HtrA1 protein RPE–Bruch’s membrane...
Community-acquired pneumonia is a well-studied condition; yet, in the urgent care setting, patient characteristics and adherence to guideline-recommended are poorly described. Within Intermountain Health, nonprofit integrated US health system based Utah, more patients present clinics (UCCs) than emergency departments (EDs) for care. We performed retrospective cohort study 1 January 2019 through 31 December 2020 28 UCCs within Utah. extracted electronic record data aged ≥12 years with ICD-10...