A5073244853- Meteorological Phenomena and Simulations
- Wind and Air Flow Studies
- Advanced Data Processing Techniques
- Noise Effects and Management
- Carcinogens and Genotoxicity Assessment
- Reservoir Engineering and Simulation Methods
- Hydrology and Watershed Management Studies
- Hydrological Forecasting Using AI
- Atmospheric chemistry and aerosols
- Heme Oxygenase-1 and Carbon Monoxide
- Cannabis and Cannabinoid Research
- Pesticide Exposure and Toxicity
- Climate variability and models
- Plant Water Relations and Carbon Dynamics
- Air Quality and Health Impacts
- Precipitation Measurement and Analysis
- Computational Physics and Python Applications
- Peroxisome Proliferator-Activated Receptors
- Body Image and Dysmorphia Studies
- Amoebic Infections and Treatments
- Toxic Organic Pollutants Impact
- Literature Analysis and Criticism
- Whitehead's Philosophy and Applications
- Chemical Safety and Risk Management
- Seismology and Earthquake Studies
NSF National Center for Atmospheric Research
2022-2024
University of Veterinary Medicine Hannover, Foundation
2008-2012
University of Veterinary Medicine Vienna
2008
Unity Hospital
2008
University of Colorado Health
1996
University of California, San Francisco
1983-1993
Center for Environmental Health
1993
San Francisco General Hospital
1983-1986
University of California System
1973
Abstract Flows in the atmospheric boundary layer are turbulent, characterized by a large Reynolds number, existence of roughness sublayer and absence well-defined viscous layer. Exchanges with surface therefore dominated turbulent fluxes. In numerical models for flows, fluxes must be specified at surface; however, not known priori parametrized. Atmospheric flow models, including global circulation, limited area large-eddy simulation, employ Monin–Obukhov similarity theory (MOST) to...
The response to eucapnic hyperventilation with subfreezing air was studied in a population based sample of 171 adults, all whom also completed respiratory questionnaire, spirometry, and skin testing. A positive the cold challenge defined as [initial FEV1-post-challenge FEV1)/initial FVC) X 100) greater than or equal 9%. Cigarette smoking response: 12 128 current ex-smokers (9.4%) versus 1 43 nonsmokers (2.3%) (p = 0.095). Among ex-smokers, significantly associated asthma 0.046). Using...
Perfluorinated organic liquids are useful as high capacity oxygen and carbon dioxide solvents. After intravenous infusion most of these perfluorinated emulsions deposited in the liver spleen a matter days, where they remain for lifetime animal. Hence, while may be isolated organ perfusion media their value artificial blood is limited. A family perfluorocarbons has now been discovered, which, although after circulation blood, leave to excreted via lungs skin days without apparent harmn
Machine learning has shown promise in reducing bias numerical weather model predictions of wind gusts. Yet, they underperform to predict high gusts even with additional observations due the right-skewed distribution Uncertainty quantification (UQ) addresses this by identifying when are reliable or needs cautious interpretation. Using data from 61 extratropical storms Northeastern USA, we introduce evidential neural network (ENN) as a novel approach for UQ gust predictions, leveraging...
Abstract Secondary organic aerosols (SOA) are formed from oxidation of hundreds volatile compounds (VOCs) emitted anthropogenic and natural sources. Accurate predictions this chemistry key for air quality climate studies due to the large contribution submicron aerosol mass. Currently, only explicit models, such as Generator Explicit Chemistry Kinetics Organics in Atmosphere (GECKO‐A), can fully represent chemical processing thousands species. However, their extreme computational cost...
We undertook a study to determine the acute effects of routine firefighting on lung function and relationship between these nonspecific airway responsiveness. For 29 firefighters from single fire station, we calculated concentration methacholine aerosol that caused 100% increase in specific resistance (Pc100). Over an 8-week period than measured FEV1 FVC each firefighter before after 24-hr workshift every fire. From 199 individual workshifts without fires, mean +/- 2 SD across-workshift...
Abstract Robust quantification of predictive uncertainty is a critical addition needed for machine learning applied to weather and climate problems improve the understanding what driving prediction sensitivity. Ensembles models provide estimates in conceptually simple way but require multiple training prediction, increasing computational cost latency. Parametric deep can estimate with one model by predicting parameters probability distribution does not account epistemic uncertainty....
Context: Central Cushing's syndrome is not always curable by surgery or radiation of the pituitary. Medical treatment often possible effective. Some studies revealed beneficial effects PPARγ (Peroxisome-Proliferator-Activator- Receptor-gamma)-agonist rosiglitazone (RG) in vitro studies, animal models and short term clinical studies.
Abstract Recently, machine learning techniques have been employed to develop improved models for predicting surface‐layer fluxes of momentum, heat and moisture based on field observations. Herein we explore refinement these models, in particular artificial neural networks (NN), investigate their applicability within an atmospheric large‐eddy simulation model as alternative the widely adopted standard Monin − Obukhov (MO) similarity theory. Atmospheric boundary layer (ABL) simulations under...
Abstract While convective storm mode is explicitly depicted in convection-allowing model (CAM) output, subjectively diagnosing large volumes of CAM forecasts can be burdensome. In this work, four machine learning (ML) models were trained to probabilistically classify storms into one three modes: supercells, quasi-linear systems, and disorganized convection. The ML included a dense neural network (DNN), logistic regression (LR), convolutional (CNN), semisupervised CNN–Gaussian mixture (GMM)....
AbstractObjective: A prospective study of civilian (nonfirefighter) smoke inhalation patients was carried out to test the hypotheses that: 1) absorption carbon monoxide and hydrogen cyanide from can be predicted by clinical examination historical data; and, more specifically 2) a history exposure burning synthetic polymers is an important predictor systemic levels. Methods: The conducted over three-year period at six urban hospitals. Patients with or without burns who were exposed within...
Non-parasitic cysts of the spleen are rarely encountered and present a diagnostic problem interesting enough to make report such case justifiable. In comprehensive review world literature up January 1939, Fowler found only 137 examples non-parasitic splenic cysts. 800 splenectomies performed at Mayo Clinic from 1904 1934, 4 were found, an incidence 0.5 per cent. Report Case History: A white female, single, aged 25, was admitted Nov. 5, 1940, for possible appendectomy. On 2, she had...
In rats and humans chronically exposed to large amounts of PCB (polychlorinated biphenyls) PCDF dibenzofurans), the urinary excretion uroporphyrin coproporphyrin are altered. However, porphyrin in after acute transient low level exposure has not been evaluated. Following such an which bystanders firefighters were contact with smoke from a transformer fire, we surveyed 90 self-referred individuals by questionnaire determining single 24 hour 2-4 weeks fire. Questionnaire variables that...
Low prececal digestibility of starch leads to a higher flux into the hindgut, causing forced microbial fermentation, energy losses, and meteorism. For exocrine pancreatic insufficiency (EPI), lack amylase can be compensated mostly by hindgut fermentation starch. Even in pigs with complete loss secretion, over entire tract is reaching levels controls. To optimize diets for human patients EPI, proportion that digested ileum important. Minipigs were fitted an ileocecal reentrant fistula (n = 8)...
There is deep concern about the long term health effects of exposure to phenoxy herbicides and contaminant TCDD; however, there considerable scientific medical uncertainty regarding from these chemicals. are at least ten ongoing studies on reproduction, morbidity mortality as well tissue concentrations TCDD that attempting determine chemicals (see Table 2). Appropriate efforts should be made prevent human environmental decontaminate environment while awaiting results investigations. Animal...
The NBT-PABA test is an established method for diagnosis of pancreatic exocrine insufficiency. In the present study was used to and compare efficacy two multienzyme preparations (product A B) differing in galenic preparation minipigs which insufficiency (PEI) induced by duct ligation. Without enzyme substitution no distinct increase PABA found blood after oral administration NBT-PABA. Administration both led a clear dose dependent rise PABA-concentrations blood. Interestingly, showed...
Robust quantification of predictive uncertainty is critical for understanding factors that drive weather and climate outcomes. Ensembles provide estimates can be decomposed physically, but both physics machine learning ensembles are computationally expensive. Parametric deep estimate with one model by predicting the parameters a probability distribution do not account epistemic uncertainty.. Evidential learning, technique extends parametric to higher-order distributions, aleatoric model....