A5004829942- Plant biochemistry and biosynthesis
- Plant Gene Expression Analysis
- Photosynthetic Processes and Mechanisms
- Plant Molecular Biology Research
- Traditional Chinese Medicine Analysis
- Plant Stress Responses and Tolerance
- Insect-Plant Interactions and Control
- Plant Reproductive Biology
- Phytochemistry and Biological Activities
- Fungal Biology and Applications
- Natural product bioactivities and synthesis
- Medicinal Plant Pharmacodynamics Research
- Civil and Geotechnical Engineering Research
- Plant tissue culture and regeneration
- Microbial Metabolism and Applications
- Flavonoids in Medical Research
- Corrosion Behavior and Inhibition
- Molecular Biology Techniques and Applications
- Land Use and Ecosystem Services
- Phytochemicals and Antioxidant Activities
- Transgenic Plants and Applications
- Phytochemical Studies and Bioactivities
- Biochemical and biochemical processes
- Free Radicals and Antioxidants
- Medicinal Plants and Bioactive Compounds
Shaanxi Normal University
2016-2025
Xinjiang Agricultural University
2024-2025
Shanxi Agricultural University
2025
Shanxi Academy of Building Research
2025
International Peace Maternity & Child Health Hospital
2024
Shanghai Jiao Tong University
2024
Shanghai Medical College of Fudan University
2024
Tianjin University of Traditional Chinese Medicine
2023-2024
Lanzhou University
2011-2022
Jiangsu Academy of Agricultural Sciences
2022
Abstract MicroRNAs (miRNAs) are small non-coding RNA molecules that function as diverse endogenous gene regulators at the post-transcriptional level. In past two decades, research effort on miRNA identification, and evolution has soared, so demand for databases. However, current plant databases suffer from several typical drawbacks, including a lack of entries many important species, uneven annotation standards across different abundant questionable entries, limited annotation. To address...
MYC2 is a core transcription factor in the plant response to jasmonates. It also functions secondary metabolism and various processes for growth development. However, knowledge about its role Salvia miltiorrhiza still very limited. We determined that biosynthesis of salvianolic acid B (Sal B) was strongly induced two-month-old transgenic plants over-expressed SmMYC2. In roots line 12 SmMYC2 (OEM-12), Sal concentration as high 5.95±0.07 mg g-1, level 1.88-fold higher than control had been...
Chronic inflammation is a significant contributor to the development of cancer, cardiovascular disease, diabetes, obesity, autoimmune inflammatory bowel and other illnesses. In academic field, there constant demand for effective methods alleviate inflammation. Astragalin (AST), type flavonoid glycoside that primary component in several widely used traditional Chinese anti-inflammatory medications clinical practice, has garnered attention from numerous experts scholars. This article focuses...
Jasmonates (JAs) are integral to various defense responses and induce biosynthesis of many secondary metabolites. MYC2, a basic helix-loop-helix (bHLH) transcription factor (TF), acts as transcriptional activator JA signaling. MYC2 is repressed by the JASMONATE ZIM-domain (JAZ) proteins in absence JA, but de-repressed protein complex SCFCOI1 on perception JA. We previously reported that overexpression SmMYC2 promotes production salvianolic acid B (Sal B) Salvia miltiorrhiza. However,...
Phenolic acids and tanshinones are active principles in Salvia miltiorrhiza Bunge administered for cardiovascular cerebrovascular diseases. Jasmonic acid (JA) promotes secondary metabolite accumulation, but the regulatory mechanism is unknown S. miltiorrhiza. We identified characterized JA-responsive gene SmMYB97. Multiple sequence alignment phylogenetic tree analyses showed that SmMYB97 was clustered with AtMYB11, AtMYB12, ZmP1 subgroup S7 regulating flavonol biosynthesis. highly expressed...
Transcription factors that include myeloblastosis (MYB), basic helix-loop-helix (bHLH), and tryptophan-aspartic acid (WD)-repeat protein often form a ternary complex to regulate the phenylpropanoid pathway. However, only few MYB bHLH members involved in biosynthesis of salvianolic B (Sal B) have been reported, little is known about Sal pathway regulation by WD40 transparent testa glabra 1 (TTG1)-dependent transcriptional complexes Salvia miltiorrhiza. We isolated SmTTG1 from species for...
It is difficult to accurately estimate the spatial distribution of carbon dioxide (CO2) at grid scale because lack city-level statistical data. In this paper, CO2 emission regions were devided into urban area, industrial area and rural in order calculate emissions. addition, a more accurate calculation model for energy-related emissions was proposed through integrating nighttime light datasets land use The maps estimated different compared examined using dependence overlay methods understand...
The coupling between urbanization and the eco-environment plays an important role in advancing China's urbanization. This study applies systems theory to build a set of indicators for uses entropy method determine weights indicators. Furthermore, coordination degree model, spatial autocorrelation decoupling model are used comprehensively analyse spatial–temporal differentiation China from 2001 2016. results indicate that during period, level eastern was higher than other regions, while...
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MicroRNAs (miRNAs) are a class of endogenous small RNAs that regulate the expression target genes post-transcriptionally; they known to play major roles in development and responses abiotic stress. MicroRNA408 (miR408) is conserved RNA plants; it was reported miR408 were involved stress Arabidopsis. However, Salvia miltiorrhiza has been rarely investigated. In this study, we cloned Sm-MIR408, precursor sequence, its promoter sequence from S. role tolerance salt described. The effects on...
The dried root of Salvia miltiorrhiza is a renowned traditional Chinese medicine that was used for over 1000 years in China. Salvianolic acid B (SalB) the main natural bioactive product S. miltiorrhiza. Although many publications described regulation mechanism SalB biosynthesis, few reports simultaneously focused on development. For this study, an R2R3-MYB transcription factor gene (SmMYB52) overexpressed and silenced, respectively, sterile seedlings. We found SmMYB52 significantly inhibited...
Scutellaria baicalensis Georgi is an annual herb from the genus that has been extensively used as a traditional medicine for over 2000 years in China. Baicalin and other flavonoids have identified principal bioactive ingredients. The biosynthetic pathway of baicalin S. elucidated; however, specific functions R2R3-MYB TF, which regulates synthesis, not well characterized to date. Here, S20 TF (SbMYB12), encodes 263 amino acids with length 792 bp, was expressed all tested tissues (mainly...
Radix Gentianae Macrophyllae, a traditional Chinese medicine, has been frequently used to dispel rheumatism and ease pain. There are four species of Gentiana (G. macrophylla, G. straminea, dahurica crassicaulis) recorded as herbal drugs in the Pharmacopoeia two other officinalis siphonantha) often substitutes. Currently, LC fingerprint comparison among different evidence for equivalent application these herbs lacking.To develop an HPLC method simultaneous determination iridoid secoiridoid...
MicroRNAs (miRNAs) are non-coding endogenous single-stranded RNAs that regulate target gene expression by reducing their transcription and translation. Several miRNAs in plants function secondary metabolism. The dried root of Scutellaria baicalensis Georgi is a traditional Chinese medicine contains flavonoids (baicalin, wogonoside, baicalein) as its main active ingredients. Although the S. genome sequence has been published, information regarding lacking. In this study, 12 small RNA...