- Vestibular and auditory disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Ophthalmology and Eye Disorders
- Ear Surgery and Otitis Media
- Cerebral Venous Sinus Thrombosis
- Meningioma and schwannoma management
- Glaucoma and retinal disorders
- Ear and Head Tumors
- Hearing Loss and Rehabilitation
- Brain Metastases and Treatment
- Facial Nerve Paralysis Treatment and Research
- Neuroscience of respiration and sleep
- Head and Neck Cancer Studies
- Neurofibromatosis and Schwannoma Cases
- Head and Neck Surgical Oncology
- Fetal and Pediatric Neurological Disorders
- Glioma Diagnosis and Treatment
- Cerebrospinal fluid and hydrocephalus
- Scoliosis diagnosis and treatment
- Laser Applications in Dentistry and Medicine
- Vascular Malformations Diagnosis and Treatment
- Migraine and Headache Studies
- Obstructive Sleep Apnea Research
- Cardiovascular Syncope and Autonomic Disorders
- Proteoglycans and glycosaminoglycans research
National Taiwan University Hospital
2015-2025
Far Eastern Memorial Hospital
2009-2025
GTx (United States)
2015
National Taiwan University
2002-2011
National Science and Technology Council
2002
Taipei Hospital
1992-1995
The University of Tokyo
1990-1992
Chelsea and Westminster Hospital
1990
<h3>Background</h3> The staging of Ménière's disease that was proposed by the American Academy Otolaryngology–Head and Neck Surgery in 1995 based on arithmetic mean pure-tone thresholds at 0.5, 1.0, 2.0, 3.0 kHz using worst audiogram during 6-month interval before treatment. stages were classified as follows: stage I, a 4-tone average less than 26 dB; II, to 40 III, 41 70 IV, more dB. <h3>Objective</h3> Because saccule, next cochlea, is second most frequent site hydrops formation, we wanted...
Vestibular evoked myogenic potential (VEMP) is applied to explore the integrity of sacculocollic reflex. Although tests evaluate vestibular-ocular reflex pathway have shown that vestibular function adversely affected by aging, VEMP, in this study, used as a novel test define how aging influences pathway.Prospective study.Academic tertiary referral center.Eighty normal subjects, equally divided into four groups according their age, were enrolled study. Group I included patients aged <20...
Abstract Objective/Hypothesis Vestibular evoked myogenic potential (VEMP) testing has become a well‐established test to explore the sacculo‐collic pathways in human. The aim of present study is establish clinical indication for saccular hydrops by VEMP testing. Study Design Prospective study. Methods Ten patients (three men and seven women) with Meniere's disease 10 (four six sudden deafness were admitted given pure‐tone audiometry daily. Interaural amplitude difference over sum amplitudes...
In Brief Objective Vestibular evoked myogenic potential (VEMP) has become a diagnostic tool to evaluate the integrity of sacculo-collic reflex. To obtain more consistent VEMP response in normal-hearing subjects, we examine whether clicks or short tone bursts are effective eliciting responses. Design Prospective study. Twenty-nine volunteers (58 ears) were given tests. Clicks and presented alternately evoke VEMPs. The latencies peak p13 n23, peak-to-peak interval amplitude (p13-n23) measured...
Objective: This study applied ocular vestibular-evoked myogenic potential (oVEMP) tests in healthy subjects of various ages to measure the effect aging on oVEMPs quantitatively. Study Design: Prospective study. Setting: University hospital. Subjects: Seventy with ranging from 24 76 years were divided into 6 groups by decade. Each group consisted 10 1 decade except 20 60 69 years. Main Outcome Measures: All underwent oVEMP using bone-conducted vibration stimuli. Results: 20-59 showed 100%...
In Brief Objectives: The aim of this study was to determine whether bone-conducted vibration (BCV) or air-conducted sound (ACS) is the optimal mode for eliciting both ocular vestibular-evoked myogenic potentials (oVEMPs) and cervical VEMPs (cVEMPs). Design: Twelve healthy volunteers, five patients with unilateral chronic otitis media, 10 Meniere disease underwent oVEMP cVEMP tests using ACS BCV stimulation modes in a random order. Results: controls, at Fz had significantly higher response...
This study investigated the localization and prevalence of hydrops formation in 20 patients with unilateral Ménière’s disease using a battery tests, including audiometry, caloric, ocular vestibular evoked myogenic potential (oVEMP) cervical VEMP (cVEMP) tests. The latter two tests used air-conducted sound (ACS) bone-conducted vibration (BCV) as stimuli. Thirteen (65%) had abnormal hearing 4-tone average >26 dBHL. In caloric test, 4 (20%) responses, canal paresis 3 areflexia 1 patient....
Both vestibular schwannoma (VS) and Meniere's disease (MD) patients underwent hydrops MRI to clarify the relationship between VS endolymphatic (EH).
ABSTRACT Objective This study aimed to find biomarkers for assessing migrainous features, that is, headache, sensitivity sound and light (phono‐ photophobia) visual aura in vestibular migraine (VM) patients. Design A retrospective cohort study. Setting University hospital. Participants total of 400 definitive VM patients were classified into four groups based on the number features. Group ( n = 45) had one feature (migrainous headache). B 70) headache along with phono‐ photophobia, while C...
Abstract Objectives/Hypothesis Despite its widespread application in the posterior fossa tumor, study of vestibular evoked myogenic potential (VEMP) cases stroke remains scarce. The purpose was to establish role VEMP patients with brainstem stroke. Study Design Retrospective study. Methods Patients acute vertigo were admitted and underwent a battery auditory tests including caloric tests; then they surveyed by magnetic resonance imaging scan. Seven (two men five women) demonstrated as having...
In Brief Objectives: Because active and tonic sternocleidomastoid (SCM) muscle contraction is essential for recording the vestibular evoked myogenic potential (VEMP), false-negative VEMPs are sometimes encountered in those who cannot sustain SCM by head elevation. Hence, goal of this study was to investigate whether effortless rotation method can replace elevation eliciting VEMP responses. Design: Twenty healthy volunteers underwent testing, using monaural tone burst stimulation. First,...
Objective To investigate the effect of chronic noise exposure on vestibular‐evoked myogenic potentials. Study Design Prospective study. Subjects and Methods Twenty patients with noise‐induced hearing loss, presenting as bilateral notched audiogram at 4 kHz, underwent audiometry, caloric, potential tests. Results Caloric tests revealed abnormal responses in nine (45%) 10 (50%) patients, respectively. However, when both results were considered together, rate reached 70% (14 20). The threshold...
Abstract Objectives/Hypothesis: Because the sacculocollic reflex is a descending pathway passing through territory of basilar artery, aim study was to investigate whether hypoperfusion affects this by applying vestibular evoked myogenic potential (VEMP) testing in patients with artery migraine. Study Design: A prospective from May 2000 April 2002. Methods: Twenty were diagnosed as having migraine according criteria International Headache Society and literature. Eight male 12 female patients,...
Conclusion. The tumor size of acoustic neuroma correlates with cochleovestibular deficits. Those tumors global frequency hearing loss, bilateral gaze nystagmus, or absent caloric and VEMP responses may indicate a >2.5 cm. Objective. This study aimed to investigate the correlation between deficits neuroma. Patients methods. A total 44 patients were enrolled in this study. Pure tone audiometry, electronystagmography, test, vestibular evoked myogenic potential (VEMP) MRI conducted. Results....