A5030626022- EEG and Brain-Computer Interfaces
- Neuroscience and Neural Engineering
- Cardiac Arrest and Resuscitation
- Neural dynamics and brain function
- Vestibular and auditory disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Non-Invasive Vital Sign Monitoring
- Spine and Intervertebral Disc Pathology
- ECG Monitoring and Analysis
- Spinal Fractures and Fixation Techniques
- Analog and Mixed-Signal Circuit Design
- Ophthalmology and Eye Disorders
- Heart Rate Variability and Autonomic Control
- Advanced MRI Techniques and Applications
- Neuroscience and Music Perception
- Urinary Bladder and Prostate Research
- Pain Mechanisms and Treatments
- Blind Source Separation Techniques
- Mechanical Circulatory Support Devices
- Peripheral Nerve Disorders
- Scoliosis diagnosis and treatment
- Neuroscience and Neuropharmacology Research
- Hemodynamic Monitoring and Therapy
- Context-Aware Activity Recognition Systems
- Phonocardiography and Auscultation Techniques
National Taiwan University
2016-2025
National Defense Medical College
2022
National Defense Medical Center
2022
Far Eastern Memorial Hospital
2016
Restaurant Opportunities Centers United
2013
National Taiwan University Hospital
2012
GTx (United States)
2008-2011
Institute of Biomedical Sciences, Academia Sinica
2007
Rapid eye movement (REM) sleep behavior disorder (RBD) is associated with Parkinson’s disease (PD). In this study, a smartwatch-based sensor utilized as convenient tool to detect the abnormal RBD phenomenon in PD patients. Instead, questionnaire quality assessment and physiological indices, such stage, activity level, heart rate, were measured smartwatch sensors. Therefore, device can record comprehensive data, offering several advantages ubiquity, long-term monitoring, wearable convenience....
ObjectiveWe aimed to determine the reliability of using Fibrosis-4 (FIB-4) index in COVID-19 patients without underlying liver illness.MethodWe employed multivariate logistic regression identify variables that exhibited statistically significant influence on ultimate outcome. Multilayer perceptron analysis was develop a prediction model for FIB-4 concerning ICU admission and intubation rates. However, scarcity cases rendered assessment mortality rate unfeasible. We plotted ROC curves analyze...
In Brief Objectives: The aim of this study was to determine whether bone-conducted vibration (BCV) or air-conducted sound (ACS) is the optimal mode for eliciting both ocular vestibular-evoked myogenic potentials (oVEMPs) and cervical VEMPs (cVEMPs). Design: Twelve healthy volunteers, five patients with unilateral chronic otitis media, 10 Meniere disease underwent oVEMP cVEMP tests using ACS BCV stimulation modes in a random order. Results: controls, at Fz had significantly higher response...
Abstract Background The third and fourth heart sound (S3 S4) are two abnormal components which proved to be indicators of failure during diastolic period. combination using sounds with the standard ECG as a measurement ventricular dysfunction may improve noninvasive diagnosis early detection myocardial ischemia. Methods In this paper, an adaptive method based on time-frequency analysis is proposed detect presence S3 S4. Heart signals periods were analyzed Hilbert-Huang Transform (HHT). A...
Background: Total knee arthroplasty (TKA) is commonly performed for severe osteoarthritis but often results in significant postoperative swelling and discomfort, impacting early rehabilitation. Photobiomodulation therapy (PBMT), utilizing low-level laser (LLLT), has emerged as a potential adjunctive treatment to alleviate these symptoms. Methods: In this single-center, nonblinded prospective randomized clinical trial, conducted from May July 2024, 30 patients undergoing primary TKA were...
Prompt primary percutaneous coronary intervention (pPCI) is crucial for the prognosis and reduction of myocardial damage in ST-segment elevation infarction (STEMI) patients. The Coronavirus Disease 2019 (COVID-19) pandemic had multifaceted impacts on healthcare. This study assessed effects pPCI procedures clinical outcomes emergency STEMI retrospective, single-center analyzed patients who underwent from February to January 2022. COVID-19 was categorized into three periods: pre-COVID-19...
Abstract Nociceptive neuronal activation in subcortical regions has not been well investigated functional magnetic resonance imaging (fMRI) studies. The present report aimed to use the blood oxygenation level‐dependent (BOLD) fMRI technique map nociceptive responses both and cortical by employing a refined data processing method, atlas registration‐based event‐related (ARBER) analysis technique. During acquisition, 5% formalin (50 μl) was injected into left hindpaw induce nociception. ARBER...
The danger of falling among the elderly is a public concern and becoming an important issue that needs further attention. Sensors embedded in smartphones provide information about user activity, such as accelerometer which widely used fall detection. In this paper, we propose detection algorithm formed by feature extraction processing recognition processing. A total six features were calculated Four them are related to gravity vector extracted from data using low-pass filtering. As mostly...
Objectives To assess the quality and alignment of ChatGPT's cancer treatment recommendations (RECs) with National Comprehensive Cancer Network (NCCN) guidelines expert opinions. Methods Three urologists performed quantitative qualitative assessments in October 2023 analyzing responses from ChatGPT-4 ChatGPT-3.5 to 108 prostate, kidney, bladder prompts using two zero-shot prompt templates. Performance evaluation involved calculating five ratios: expert-approved/expert-disagreed NCCN-aligned...
Background Schizophrenia is a heterogeneous disorder with diverse presentations. The current and the proposed DSM-V diagnostic system remains phenomenologically based, despite fact that several neurobiological neuropsychological markers have been identified. A multivariate approach has better utility than single marker method. In this study, mismatch negativity (MMN) deficit of schizophrenia was first replicated in Han Chinese population, then MMN combined measurements to differentiate...
Falls by the elderly may result in hip fractures, paraplegia, and even death. Hence, over past few decades, considerable research has been conducted on fall detection. Here, an accelerometer-based detector is reported that fastened to a person's waist includes accelerometer, multiplexer, fifth-order low-pass Butterworth filter, microcontroller. Acceleration sensing, noise filtering, analog-to-digital conversion were performed circuitry. The processed signal was sent personal computer through...
Purpose To evaluate the response in patients undergoing SBRT using dynamic contrast‐enhanced (DCE) integrated magnetic resonance positron emission tomography (MR‐PET). Stereotactic body radiation therapy (SBRT) is efficacious as a front‐line local treatment for non‐small cell lung cancer (NSCLC). Materials and Methods We prospectively enrolled 19 tumors 17 nonmetastatic NSCLC who were receiving primary treatment. They underwent DCE‐integrated 3T MR‐PET before 6 weeks after SBRT. The...
An automatic method is presented for detecting myocardial ischemia, which can be considered as the early symptom of acute coronary events. Myocardial ischemia commonly manifests ST- and T-wave changes on ECG signals. The methods in this study are proposed to detect abnormal beats using knowledge-based features classification methods. A novel method, sparse representation-based (SRC), involved improve performance existing algorithms. comparison was made between two methods, SRC support-vector...
Falling is a common accident that can lead to serious injury among the elderly. To reduce injuries resulting from falls, automatic detection allows immediate medical assistance. Hence, various fall detectors, including body sensors and smartphones, have been developed in recent decades. In our previous study, an accelerometer-based detector was designed with high accuracy for simulated falls performed by young volunteers. However, there are significant differences between acceleration...
Abstract Cisplatin-based chemotherapy is the first-line therapy for bladder cancer. However, cisplatin resistance has been associated with recurrence of Previous studies have shown that activation FGFR and HER2 signaling are involved in cancer cell proliferation drug resistance. Smoking most common etiologic risk factor cancer, there emerging evidence smoking underlying mechanism remains elusive. Acrolein, a highly reactive aldehyde, abundant tobacco smoke, cooking fumes, automobile exhaust...