A5053542802- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Diagnosis and Treatment
- Urinary and Genital Oncology Studies
- Physics of Superconductivity and Magnetism
- Rare-earth and actinide compounds
- Renal cell carcinoma treatment
- Advanced Condensed Matter Physics
- Magnetic properties of thin films
- Magnetic and transport properties of perovskites and related materials
- Hormonal and reproductive studies
- Cancer, Lipids, and Metabolism
- Solid-state spectroscopy and crystallography
- Urological Disorders and Treatments
- High-pressure geophysics and materials
- Urologic and reproductive health conditions
- Arsenic contamination and mitigation
- Iron-based superconductors research
- Cancer-related molecular mechanisms research
- Magnetic Properties of Alloys
- Urinary Bladder and Prostate Research
- Theoretical and Computational Physics
- Estrogen and related hormone effects
- Superconducting Materials and Applications
- Advanced Chemical Physics Studies
National Taiwan University Hospital
2016-2025
Zhejiang Lab
2023-2025
Dalian Institute of Chemical Physics
2025
Chinese Academy of Sciences
2025
Jiangsu University
2020-2025
Wenzhou Medical University
2025
First Affiliated Hospital of Wenzhou Medical University
2025
Chung Shan Medical University
2025
Tianjin University
2025
Ministry of Education of the People's Republic of China
2025
Current non-invasive approaches for detection of urothelial cancers are suboptimal. We developed a test to detect neoplasms using DNA recovered from cells shed into urine. UroSEEK incorporates massive parallel sequencing assays mutations in 11 genes and copy number changes on 39 chromosome arms. In 570 patients at risk bladder cancer (BC), was positive 83% those who BC. Combined with cytology, detected 95% Of 56 upper tract cancer, 75% tested by UroSEEK, including 79% tumors. genetic...
Systematic investigation has been made on CuCl crystals prepared by different methods. The occurrence of high-pressure phases and various anomalies are found to depend sensitively the sample conditions. Four-lead electrical measurements showed that all pressure-induced thermally equilibrated studies had positive although small activation energies. A diamagnetic anomaly above 90 K over a temperature range 10-20 was observed in ac magnetic susceptibility rapidly warmed samples. sharp increase...
The pulsed-saturation method at 8.9 kMc/sec was used to measure the spin-lattice relaxation rate ${{T}_{1}}^{\ensuremath{-}1}$ for ${\mathrm{Eu}}^{2+}$, ${\mathrm{Ho}}^{2+}$, and ${\mathrm{Tm}}^{2+}$ in Ca${\mathrm{F}}_{2}$, ${\mathrm{Yb}}^{3+}$ yttrium gallium garnet, aluminum lutetium garnet; ${\mathrm{Nd}}^{3+}$ garnet ${\mathrm{Sm}}^{3+}$ lanthanum ethyl sulphate low temperatures. experimental data most cases are satisfactory agreement with theoretical predictions based on combined Van...
Aristolochic acid (AA), a component of all Aristolochia ‐based herbal medicines, is potent nephrotoxin and human carcinogen associated with upper urinary tract urothelial carcinoma (UUC). To investigate the clinical pathological characteristics AA‐induced UUC, this study included 152 UUC patients, 93 whom had been exposed to AA based on presence aristolactam‐DNA adducts in renal cortex. Gene sequencing was used identify tumors A:T‐to‐T:A transversions TP53 , mutational signature AA. Cases...
Rationale: Mesenchymal stem cells (MSCs) have been the focus of many studies because their abilities to modulate immune responses, angiogenesis, and promote tumor growth metastasis. Our previous work showed that gastric cancer MSCs (GCMSCs) promoted escape by secreting IL-8, which induced programmed cell death ligand 1 (PD-L1) expression in GC cells. Mounting evidence has revealed PD-L1 is related intrinsic properties. Here, we investigated whether GCMSCs maintained a pool (CSCs) through...
To evaluate effects of stopping smoking on the outcome nonmuscle-invasive bladder cancer, as cigarette is a risk factor for cancer and little known about whether reduces recurrence or progression.Between January 1997 July 2005, 297 men with primary were treated transurethral resection (TUR); their status before after diagnosis was obtained by post hoc questionnaire interview. 'Quitters' those who ceased within year 3 months diagnosis. Ex-smokers more than Several pathological clinical...
There are still no effective therapies for hyposalivation caused by irradiation. In our previous study, bone marrow stem cells can be transdifferentiated into acinar-like in vitro. Therefore, we hypothesized that transplantation with or may help functional regeneration of salivary glands. Bone were labeled nanoparticles and directly co-cultured acinar to obtain cells. total, 140 severely combined immune-deficiency mice divided 4 groups cell therapy experiments: (1) normal mice, (2) receiving...
The zero-field spin relaxation of positive muon is measured in spin-glasses $\mathrm{Au}\mathrm{Fe}$ and $\mathrm{Cu}\mathrm{Mn}$. A stochastic theory a random dilute system formulated to deduce the correlation time Fe (or Mn) moments. observed increases rapidly from ${10}^{\ensuremath{-}10}$ sec (at $T\ensuremath{\sim}1.2{T}_{g}$) ${10}^{\ensuremath{-}5}$ $T\ensuremath{\sim}0.5{T}_{g}$), showing sharp slowing down fluctuation around ${T}_{g}$.
Deregulated micro RNA s and their roles in carcinogenesis cancer progression have attracted much attention. In previous studies conducted our laboratory, the Illumina Solexa massively parallel signature sequencing of mi RN omes nontumor hepatocellular carcinoma ( HCC ) tissues revealed that miR‐486‐5p was significantly downregulated , but its role development remains unknown. this study, levels matched control tissues, seven cell lines QGY ‐7701, ‐7703, ‐7404, SMMC ‐7721, Huh7, HepG2, PCL /...
Abstract Objective To compare tumor characteristics and clinical outcome of patients with cervical locally advanced adenocarcinoma ( AC )/adenosquamous carcinoma ASC ) squamous cell SCC ). Design Retrospective study. Setting National Taiwan University Hospital, Taipei, Taiwan. Population All n = 35), or 194) FIGO stage ≥IIB who received definitive radiotherapy concurrent chemoradiotherapy CCRT from January 1995 to December 2009. Method Medical histopathological record review. Main measures...
Accelerated glucose metabolism is critical in hepatocarcinogenesis, but the utilities of different transporter inhibitors treating hepatocellular carcinoma (HCC) remain largely uncharacterized. In this study, we examined a collection and found differential anti-HCC effects among these compounds. Canagliflozin (CANA), phloretin, WZB117 decreased cellular influx, only CANA showed potent growth inhibition HCC, which indicated glucose-independent mechanism. Notably, that treatment significantly...
Abstract Purpose The Systemic Immune-inflammatory Index (SII) and Geriatric Nutritional Risk (GNRI) have undergone comprehensive examination validation in forecasting the outcomes of diverse medical conditions. Nevertheless, correlation between combined use GNRI SII metrics hip fractures has yet to be elucidated. This study aimed determine whether amalgamation scores constitutes an independent prognostic factor for elderly patients with fractures. Methods We conducted a retrospective...
Abstract BACKGROUND The modulatory effects and molecular mechanisms of curcumin (CCM) on the cytotoxicity chemotherapeutic agents to prostate cancer cells were explored. METHODS combined CCM examined by three different administration schedules (one concurrent two sequential treatments) in androgen‐independent (AIPC) (PC‐3 DU145). Alteration cell cycle progression, protein levels, transcriptional activation PC‐3 assayed flow cytometry, Western blotting, gel shift assay, respectively. RESULTS...
${\mathit{T}}_{\mathit{c}}$ and ${\mathit{dT}}_{\mathit{c}}$/dP have been systematically measured for fully oxygenated R${\mathrm{Ba}}_{2}$${\mathrm{Cu}}_{3}$${\mathrm{O}}_{7\mathrm{\ensuremath{-}}\mathrm{\ensuremath{\delta}}}$ (R-123) with R=Yb, Tm, Ho, Dy, Gd, Sm, Nd. has observed to increase from 88 94 K increasing radius of the R ion (r) 0.98 1.12 \AA{}. Based on lattice strains our data, we calculated series R-123 compared them ${\mathit{T}}_{\mathit{c}}$. Good agreement between...