A5078947702- Advanced MRI Techniques and Applications
- Energy Harvesting in Wireless Networks
- Functional Brain Connectivity Studies
- Atomic and Subatomic Physics Research
- Advanced NMR Techniques and Applications
- Electromagnetic Compatibility and Measurements
- Nuclear Physics and Applications
- Wireless Body Area Networks
- Microwave Imaging and Scattering Analysis
- Dementia and Cognitive Impairment Research
- Ultrasonics and Acoustic Wave Propagation
- Electrochemical Analysis and Applications
- Integrated Circuits and Semiconductor Failure Analysis
- Optical Imaging and Spectroscopy Techniques
- Electromagnetic Fields and Biological Effects
- Microwave and Dielectric Measurement Techniques
- Non-Destructive Testing Techniques
Western University
2019-2023
Institute of Biophysics
2023
<h3>BACKGROUND AND PURPOSE:</h3> Superagers are defined as older adults with episodic memory performance similar or superior to that in middle-aged adults. This study aimed investigate the key differences discriminative networks and their main nodes between superagers cognitively average elderly controls. In addition, we sought explore sensitivity detecting these functional activities across at 3T 7T MR imaging fields. <h3>MATERIALS METHODS:</h3> Fifty-five subjects 80 years of age were...
fMRI is typically not performed at field strengths < 1.5T due to low magnetic susceptibility contrast and inadequate gradient performance. Leveraging the high-performance set of a head-only 0.5T MRI, feasibility motor task based was evaluated using 4mm isotropic GRE-EPI acquisition. Activated regions within PMC were consistent with expected behaviour. Furthermore, significant change in signal during activation 1.8+/-0.4% measured an ROI activated voxels. These results suggest that BOLD...
Motivation: Accurate knowledge of T2* relaxation times is important for optimizing contrast and SNR in multi-echo gradient echo sequences. Goal(s): To measure the nominal parameter at 0.5 T over subregions brain. Approach: A 2 mm isotropic 3D GRE sequence was acquired 5 healthy volunteers. estimates were computed regions interest using a mono-exponential fit. Results: gray (86&plusmn;8 ms) white (78&plusmn;5 matter are good agreement with previously published measurements mid-field....
Motivation: Resting state fMRI (rs-fMRI) provides vital neurological information in acute care. Goal(s): To demonstrate the feasibility of rs-fMRI at 0.5T. Approach: Repeated acquisitions two healthy volunteers (n = 6, n 4) were acquired 0.5T using a 31 min EPI based protocol. Results: All eleven well-established resting networks identified. Sensorimotor and language very reliable across scans for both with intersession intra-class correlation coefficient values &gt; 0.5. Impact: is...
In this article, an ultralow-frequency electric field probe capable of measuring time-varying gradient coil induced fields in a tissue-mimicking material was constructed, calibrated, and validated. This consisted 2 cm short dipole antenna followed by instrumentation amplifier. The designed amplifier had gain 100 cutoff frequency 31 kHz. fabricated on four-layer printed circuit board (PCB), FR4 thickness 1.57 mm copper 35 μm. A waterproofed 3-D holder used to cover the electronics expose tip...
Initial investigation of effects due to reduced TR on RSNs at a 0.5 T MR scanner. There was decrease in detected regions within specific networks for the 3 data as reduced. However, when tSNR approximately 17 ignoring expected decrement compared data, there an increase positive detection shorter TR. These result show possibility extracting true low field scanner using TRs which can lead efficient sequence design since T1 is shortened fields.
Preliminary evaluation of the feasibility to perform resting state BOLD fMRI at a low field (0.5 T) MR scanners equipped with high-performance gradient system by investing detection capability RSNs lower strengths. There was an overall deterioration in number detected regions within all as tSNR decreased. However, 0.5 Evry that will be used for experimental studies offer better SNR efficiency than modelled cases considered here suggesting reasonable extracting can potentially provide...
Gradient-recalled echo (GRE) echo-planar imaging (EPI) is an efficient MRI pulse sequence that commonly used for several enticing applications, including functional (fMRI), susceptibility-weighted (SWI), and proton resonance frequency (PRF) thermometry. These applications are typically not performed in the mid-field (<1 T) as longer T2* lower polarization present significant challenges. However, recent developments of scanners equipped with high-performance gradient sets offer possibility to...
In this work ultra-low frequency probes for measuring time-varying electric field produced in gradient coils were designed, fabricated and tested. A 2 cm short dipole antenna followed by an instrumentation amplifier was chosen to measure the field. The designed has a gain of 100 cutoff 31 KHz. Probes on 4-layers Printed Circuit Board (PCB), FR4 thickness 1.57 mm copper 35 μm. Verification validation performed using parallel plate capacitor with known which calculated analytically...
As a part of this work small patch antenna probe was developed to measure the variation in electric field produced by gradient coils within an MRI presence any active implantable medical devices (AIMDs). This designed, fabricated, and tested coil mimicking dB/dt exposure platform. A 2×1 cm followed instrumentational amplifier chosen fields. Probe fabricated using 4-layer PCB. The used monitor fields phantom environment. To verify observed behavior simulation study performed Sim4Life. aims...