A5069505986- Animal testing and alternatives
- Dermatology and Skin Diseases
- Advancements in Transdermal Drug Delivery
- Contact Dermatitis and Allergies
- Carcinogens and Genotoxicity Assessment
- Skin Protection and Aging
- Diabetic Foot Ulcer Assessment and Management
- Pain Mechanisms and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Complementary and Alternative Medicine Studies
- Allergic Rhinitis and Sensitization
- Metabolism and Genetic Disorders
- Food Allergy and Anaphylaxis Research
- Wound Healing and Treatments
- Skin and Cellular Biology Research
- Phytochemistry Medicinal Plant Applications
- Peroxisome Proliferator-Activated Receptors
- Circadian rhythm and melatonin
- Diet and metabolism studies
- 3D Printing in Biomedical Research
- Effects and risks of endocrine disrupting chemicals
- Biotechnology and Related Fields
- Pressure Ulcer Prevention and Management
- Tendon Structure and Treatment
- Polymer Surface Interaction Studies
Université Claude Bernard Lyon 1
2011-2020
Centre National de la Recherche Scientifique
2018-2020
Biologie Tissulaire et Ingénierie Thérapeutique
2018-2020
Biologie des Plantes et Innovation
2012
Journal Article The lipid alterations in the stratum corneum of dogs with atopic dermatitis are alleviated by topical application a sphingolipid‐containing emulsion Get access I. Popa, Popa Laboratory Dermatological Research, University Lyon‐I, Lyon, France Dr Iuliana UMR CNRS 8612, Paris XI School Pharmacy, 92290 Châtenay‐Malabry, E‐mail: iuliana.popa@u‐psud.fr Search for other works this author on: Oxford Academic Google Scholar N. Remoue, Remoue B. Osta, Osta D. Pin, Pin VetAgro Sup,...
Poly(ethylene glycol) (PEG) hydrogels have been extensively used as scaffolds for tissue engineering applications, owing to their biocompatibility, chemical versatility, and tunable mechanical properties. However, bio-inert properties require them be associated with additional functional moieties interact cells. To circumvent this need, we propose here reticulate PEG molecules poly(L-lysine) dendrigrafts (DGL) provide intrinsic cell functionalities PEG-based hydrogels. The physico-chemical...
Synopsis Objective Organotypic skin models are powerful tools for research in development, ageing and diseases. They have become more complex with the use of multiple cell types. This requires a culture medium adapted to optimize development such vitro skin. Foetal bovine serum ( FBS ) is most complete supplement existence at moment, providing once growth factors, vitamins, hormones other circulating compounds. However, this cocktail suffers from batch variability its animal origin ethically...
To overcome the current lack of in vitro models to specifically reproduce hormonal skin ageing women, and search active ingredients with innovative efficacy claim for cosmetic care, we developed a cell culture-based model by simulating menopause's decline assessed several parameters collagen metabolism.Human dermal fibroblasts were incubated media containing 17β-oestradiol, progesterone, dehydroepiandrosterone, growth hormone insulin-like factor-1 at concentrations corresponding those...
Abstract Ageing is a complex multifaceted process affecting skin functionality and structure. Several 3D organotypic culture models have reproduced ageing by inducing replicative senescence, glycation or oxidative stress. Yet, very few focused on hormonal especially the insulin‐like growth factor 1 ( IGF ‐1) signalling pathway, which has been associated with longevity in animal studies necessary for early stages of development. In this study, we built an epidermis model targeted ‐1 receptor...
The skin is a protective organ, able to decode wide range of tactile, thermal, or noxious stimuli. Some the sensors belonging transient receptor potential (TRP) family, for example, TRPV1, can elicit capsaicin-induced heat pain histamine-induced itching sensations. sensory nerve fibers, whose soma located in trigeminal dorsal root ganglia, are carry signals from skin’s receptors toward brain via spinal cord. In some cases, response environmental factors, endings might be hyper activated,...