Background: This study aimed to compare the effect of ultrasound-guided bilateral and bilevel erector spinae plane block (ESPB) on pain scores, opioid requirement, intraoperative motor-evoked potentials (MEPs), stress response surgery expressed by neutrophil-to-lymphocyte ratio (NLR) platelet-to-lymphocyte (PLR) versus standard analgesia methods following idiopathic scoliosis surgery. Methods: was a prospective, double-blinded, randomized controlled trial. Sixty patients aged 10 18 years...

This was a narrative review.

Regional anesthesia has gained increasing attention in pediatric surgery as a valuable tool for managing perioperative pain and improving surgical outcomes. This narrative review highlights the numerous advantages of regional populations, including superior control, reduced reliance on systemic opioids, fewer anesthetic-related complications, enhanced recovery profiles. Using ultrasound-guided techniques further expanded safety precision blocks children. also addresses critical concerns...

Background: The immediate postoperative period after total hip arthroplasty can be associated with significant pain. Therefore, this study aimed to evaluate the effect of pericapsular nerve block on pain management and functional recovery arthroplasty. Methods: This prospective, randomized, double-blinded, placebo-controlled trial was conducted 489 adult patients scheduled for arthroplasty, ASA 1–2, operated under spinal analgesia. Participants were assigned receive either a group (PENG) 20...

Neutrophile-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte (PLR) are the inflammatory biomarkers of stress response. In this study, we aimed to evaluate effects erector spinae plane block (ESPB) on posterior lumbar decompression stabilization by comparing NLR, PLR, postoperative pain, opioid consumption, functional recovery between sham ESPB.

This study assessed the effect of perineural dexamethasone on block duration, opioid requirement, blood glucose levels, and stress response to surgery as measured by neutrophil-to-lymphocyte ratio (NLR) platelet-to-lymphocyte (PLR), following pediatric foot ankle surgery.

This study aimed to assess the analgesic efficacy of oxycodone at doses 10 mg and 20 in dressings after surgery burn wounds. Twenty adult patients who underwent surgical treatment third-degree wounds under general anaesthesia were included. Burn treated with dressings, which was added Group 1 2. After surgery, plasma noroxycodone concentrations assayed, pain intensity assessed Numerical Rating Scale (NRS). In 1, no patient reported pain; 2, four pain. The intensity, according NRS, 1-8....

Introduction: The Pericapsular Nerve Group (PENG) block is a novel technique that allows for analgesia of the anterior hip capsule via articular branches accessory obturator nerve and femoral nerve, which have significant role in innervation capsule. A PENG (Pericapsular Nerves Group) blockade effective both adult pediatric patients. However, no studies on patients under five are available literature. Herein, we describe our experience with two dysplasia. Purpose: This study aimed to...

Introduction: This study aimed to investigate pain management, functional recovery, and stress response expressed by the neutrophile-to-lymphocyte ratio (NLR) platelet-to-lymphocyte (PLR) after popliteal artery posterior knee capsule infiltration (iPACK) block combined with adductor canal (ACB) in total arthroplasty (TKA). Patients Methods: was a prospective, double-blinded, randomised, controlled trial tertiary referral hospital. Three hundred sixty-six patients were randomly allocated into...

The main urinary cocaine metabolites are benzoylecgonine and ecgonine methyl ester. These molecules possess two chemical functional groups that can be charged within the conventional pH range, this is tertiary amine group (both) carboxylic (benzoylecgonine). We have found in range from 2 to 6 (for benzoylecgonine) 4 ester) both detected at electrified liquid-liquid interface (eLLI) by following interfacial ion transfer reactions triggered presence of concerned aqueous phase. benzene ring...

A two-dimensional layer of a three-dimensional object is reconstructed from projection data generated with fan-beam geometry and detector array. The expection value the amplitude ring artefacts given which are caused by fixed errors Simple analytic approximations given. increases near center rotation. For an application in X-ray scanners uniformity array has to be very high avoid artefacts.

A software algorithm is presented which able to suppress ring-like artefacts occur in CT fan-beam scanners when the measurements are slightly erroneous their offset or gain.

A twin-cone scanning geometry and a reconstruction method are proposed capable of multislice-reconstructing using wide cone angles.

Background and Aim: Postoperative pain after scoliosis surgery is severe usually requires long-term intravenous opioid therapy. Local anesthetic options, such as wound infiltration, are limited include neuraxial analgesia. However, they rarely used due to side effects inconsistent efficacy. We report an opioid-sparing multimodal analgesia regimen with bilateral erector spinae plane blocks. This case series evaluated the analgesic effect of bi-level blocks (ESP) in congenital neurogenic...

Oxycodone is poorly studied as an adjuvant to central blockades. The aim of this pilot study was assess the efficacy and safety oxycodone hydrochloride in epidural blockade among patients undergoing total hip arthroplasty (THA).In 11 (American Society Anesthesiologists physical status classification system II/III, age range: 59-82 years), THA conducted with using 15 mL 0.25% bupivacaine (37.5 mg) 5 mg sedation propofol infusion at a dose 3-5 mg/kg/h. After surgery, received ketoprofen 100...

Unacceptable adverse effects, contraindications to and/or ineffectiveness of World Health Organization step III "pain ladder" drugs causes needless suffering among a population cancer patients. Successful management severe pain may require invasive treatment. However, patient's refusal an procedure necessitates that clinicians consider alternative options.Intrathecal bupivacaine delivery as viable treatment intractable is well documented. There are no data on rectal use in patients or the...

Total hip arthroplasty (THA) causes extensive tissue damage and severe pain. This study aimed to assess the analgesic efficacy, adverse effects (AEs), safety of continuous intravenous (iv) oxycodone infusion with ketoprofen (injected into iv line) in patients after THA, assay serum levels.Fourteen patients, aged 59‒82 years American Society Anesthesiologists (ASA) classification I or III, underwent THA intrathecal analgesia sedation induced by propofol. After surgery, (continuous infusion)...

Introduction: Rectal tenesmus pain in cancer patients most frequently appears with colon cancer, and as a consequence of radiotherapy the hypogastrium region. Treatment opioids adjuvant analgesics is often ineffective. Patients methods: Here, we report on two female diagnosed ovary respectively, who had very severe (numerical rating scale 8-10) despite using high doses opioids, including methadone corticosteroids, anticonvulsants, antidepressants ketamine. Results: In both patients,...