A5007914648- Biotin and Related Studies
- Muscle Physiology and Disorders
- Advanced Proteomics Techniques and Applications
University of Wisconsin–Madison
2022-2023
Single-cell proteomics has emerged as a powerful method to characterize cellular phenotypic heterogeneity and the cell-specific functional networks underlying biological processes. However, significant challenges remain in single-cell for analysis of proteoforms arising from genetic mutations, alternative splicing, post-translational modifications. Herein, we have developed highly sensitive functionally integrated top–down comprehensive single cells. We applied this muscle fibers (SMFs)...
Abstract Single-cell proteomics has emerged as a powerful method to characterize cellular phenotypic heterogeneity and the cell-specific functional networks underlying biological processes. However, significant challenges remain in single-cell for analysis of proteoforms arising from genetic mutations, alternative splicing, post-translational modifications. Herein, we have developed highly sensitive functionally integrated top-down comprehensive single cells. We applied this muscle fibers...