- Musculoskeletal pain and rehabilitation
- Pain Management and Treatment
- Pain Mechanisms and Treatments
- Pain Management and Placebo Effect
- Stroke Rehabilitation and Recovery
- Transcranial Magnetic Stimulation Studies
- Virtual Reality Applications and Impacts
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Eating Disorders and Behaviors
- Action Observation and Synchronization
- Impact of Technology on Adolescents
- Motor Control and Adaptation
- Botulinum Toxin and Related Neurological Disorders
- Muscle activation and electromyography studies
- Pediatric Pain Management Techniques
- Migraine and Headache Studies
- Neurology and Historical Studies
- Psychology, Coaching, and Therapy
- Body Image and Dysmorphia Studies
- Ocular and Laser Science Research
- Sexuality, Behavior, and Technology
- Psychosomatic Disorders and Their Treatments
- Infrared Thermography in Medicine
- Health, psychology, and well-being
- Circular RNAs in diseases
LWL-Universitätsklinikum Bochum
2016-2025
Ruhr University Bochum
2015-2025
Central Institute of Mental Health
2014-2025
Heidelberg University
2013-2025
University Hospital Heidelberg
2013-2025
University Hospitals of the Ruhr-University of Bochum
2023
Justus-Liebig-Universität Gießen
2021
Klinik und Poliklinik für Neurologie
2021
RWTH Aachen University
2021
Charité - Universitätsmedizin Berlin
2021
Phantom limb pain (PLP) is a common consequence of amputation and difficult to treat. Mirror therapy (MT), procedure utilizing the visual recreation movement lost by moving intact in front mirror, has been shown be effective reducing PLP. However, neural correlates this effect are not known.We investigated effects daily mirror training over 4 weeks 13 chronic PLP patients after unilateral arm amputation. Eleven participants performed hand lip movements during functional magnetic resonance...
Extended viewing of movements the intact hand in a mirror as well motor imagery has been shown to decrease pain phantom patients. We used functional magnetic resonance imaging assess neural correlates mirrored, imagined and executed 14 upper extremity amputees - 7 with limb (PLP) without (non-PLP) 9 healthy controls (HC). Executed movement activated contralateral sensorimotor area all three groups but ipsilateral cortex was only non-PLP HC group. Mirrored seen not PLP. Imagined supplementary...
Professional football is a contact sport with high risk of injury. This study was designed to examine the contribution stress and recovery variables as assessed Recovery-Stress Questionnaire for Athletes (RESTQ-Sport) injury in professional players. In prospective, non-experimental cohort design, 22 players highest German league were observed over course 16 months. From January 2010 until April 2011, completed RESTQ-Sport total 222 times monthly intervals. addition, data by medical staff...
In the so-called rubber hand illusion, synchronous visuotactile stimulation of a visible together with one's own hidden elicits ownership experiences for artificial limb. Recently, advanced virtual reality setups were developed to induce illusion (VHI). Here, we present functional imaging data from sample 25 healthy participants using new device VHI in environment magnetic resonance (MRI) system. order evaluate neuronal robustness varied degree synchrony between visual and tactile events...
Synopsis Low back pain (LBP) is an important medical and socioeconomic problem. Impaired sensorimotor control has been suggested to be a likely mechanism underlying development and/or maintenance of pain. Although early work focused on the structural functional abnormalities within musculoskeletal system, in past 20 years there increasing realization that patients with LBP might also have extensive neuroplastic changes central nervous system. These include related both structure (eg, gray...
Most patients with amputation (up to 80%) suffer from phantom limb pain postsurgery. These are often multimorbid who also have multiple risk factors for the development of chronic a medicine perspective. Surgical removal body part and sectioning peripheral nerves result in lack afferent feedback, followed by neuroplastic changes sensorimotor cortex. The experience severe pain, peripheral, spinal, cortical sensitization mechanisms, scheme contribute pain. Psychosocial may affect course...
The presence of perceptual sensitization and related brain responses was examined in 14 chronic low back pain (CLBP) patients 13 healthy controls comparable age sex. Multichannel EEG recordings ratings were obtained during the presentation 800 painful electrical intramuscular intracutaneous stimuli each to left m. erector spinae extensor digitorum. Perception thresholds not significantly different between two groups, though showed more sensitization. Across all stimulation conditions, a...
Stress-induced analgesia (SIA) refers to a reduced pain response after stress exposure, which is mediated by descending pain-inhibitory circuits and may be an indicator of adequate centrally control. We used functional magnetic resonance imaging assess brain mechanisms SIA in 21 healthy participants. Using block design series mildly painful pressure stimuli were applied the left medial phalanx second digit during imaging. Mental arithmetic combined with increasing levels noise was as...
Mirror training and movement imagery have been demonstrated to be effective in treating several clinical conditions, such as phantom limb pain, stroke-induced hemiparesis, complex regional pain syndrome. This article presents an augmented reality home-training system based on the mirror treatment approaches for hand training. A head-mounted display equipped with cameras captures one held front of body, mirrors this hand, displays it real time a set four different tasks: (1) flexing fingers...
The experience of post-amputation pain such as phantom limb (PLP) and residual (RLP), is a common consequence amputation, its presence has negative effects on person's well-being. continuity hypothesis dreams suggests that the aversive experiences in waking state should be reflected dream content, with recalled body representation reflecting cognitive proxy impact. In present study, we epidemiologically assessed other amputation-related information well sample 3,234 unilateral amputees. Data...
One of the most common forms chronic pain is back pain. Until now, nothing has been known about influence visualizing one's own on perception at this site. We tested 18 patients with and healthy controls, by implementing online video feedback during painful pressure subcutaneous electrical stimuli over trapezius muscle. Pain threshold tolerance were assessed. Pressure stimulation intensity was set to 50% above threshold. Subcutaneous 70% Subjects had rate unpleasantness after each block an...
Abstract In the rubber hand illusion (RHI), transient embodiment of an artificial is induced. An often-used indicator for this effect “proprioceptive drift”, a localization bias real towards hand. This measure suggests that attracted by Principles multisensory integration, however, rather suggest conflicting sensory information combined in “compromise” fashion and hands should be each other. Here, we used new variant RHI paradigm which participants pointed at Our results indicate perceived...
Besides all visible somatic manifestations, distorted body representation is a key symptom for anorexia nervosa (AN). Body can be divided into conscious component, image, and an unconscious action-related one, schema. As behavioral studies already explored the impact of image in AN, we aimed to explore whether distortion also extends This study first with unbiased measurement schema homogeneous sample AN patients.Twenty-three patients diagnosed 23 healthy controls (HC) walked through door...
Abstract Phantom limb pain (PLP) accounts for a significant reduction in quality of life and is difficult to treat. Prosthesis use has been shown negatively covary with PLP. Recent research on body perception amputees suggest that prosthesis ownership, defined as the extent which experienced being part rather than an artificial device foreign body, might interact We used survey data from 2383 unilateral prosthesis-using upper-limb or lower-limb performed regression analyses determine...
The perceived lack of control over the experience pain is arguably-one major cause agony and impaired life quality in patients with chronic disorders as fibromyalgia (FM). way affects subjective well underlying neural mechanisms have so far not been investigated pain. We used functional magnetic resonance imaging (fMRI) to examine correlates self-controlled compared computer-controlled heat healthy controls (HC, n = 21) FM (n 23). Contrary HC, failed activate brain areas usually involved...
Previous studies have repeatedly found distinct brain morphometric changes in patients with fibromyalgia (FM), mainly affecting gray and white matter abnormalities areas related to sensory affective pain processing. However, few thus far linked different types of structural not much is known about behavioral clinical determinants that might influence the emergence progression such changes.
Abstract Introduction: Previous investigations on pain modulatory effects of the rubber hand illusion (RHI) yielded mixed results. However, these studies used separate stimuli to induce and RHI. Using a visual-thermal stimulation approach, illusion-inducing stimulus was simultaneously which ensured that participants focused entirely stimulus. Objectives: In this study, we investigated time course modulation induced by illusionary body ownership over artificial hands using RHI influence...
Abstract Phantom limb pain (PLP) is a common consequence of the amputation limb. Individuals with congenital absence (here: amputees), however, seem to rarely experience PLP. Previous results suggest that PLP in waking state affects recalled body appearance dreams individuals acquired amputation, being associated recall an impaired rather than intact body. However, it remains unclear how amputees – who never experienced and their dreams. In present cross-sectional study, we assessed...