A5064632837- Bone Tissue Engineering Materials
- Additive Manufacturing and 3D Printing Technologies
- Surface Modification and Superhydrophobicity
- Silicone and Siloxane Chemistry
- Polymer Surface Interaction Studies
- Aerogels and thermal insulation
- Periodontal Regeneration and Treatments
- biodegradable polymer synthesis and properties
- 3D Printing in Biomedical Research
- Electrospun Nanofibers in Biomedical Applications
- Orthopedic Infections and Treatments
- Optical Coatings and Gratings
- Dental Implant Techniques and Outcomes
- Bone and Dental Protein Studies
- Graphene and Nanomaterials Applications
- Orthopaedic implants and arthroplasty
Sichuan University
2021-2024
Fujian Agriculture and Forestry University
2014-2015
The guided bone regeneration (GBR) concept has been extensively utilized to treat periodontal defects in clinical practice. However, the repair efficacy of currently available GBR membranes is often compromised by their limited alveolar potential, insufficient mechanical strength and inadequate space maintenance duration. In this paper, a novel hybrid bi-layer scaffold was fabricated using electrospun polycaprolactone/gelatine (PCL/Gel) nanofibre combined with 3D printed...
Abstract Extrusion-based three-dimensional (3D) printing of gelatin (Gel) is crucial for fabricating bone tissue engineering scaffolds via additive manufacturing. However, the thermal instability Gel remains a persistent challenge, as it tends to collapse at mild temperatures. Current approaches often involve simply mixing particles with various materials, resulting in biomaterial inks that lack uniformity and have inconsistent degradation characteristics. In this study, acetic acid was used...
Environment-resistant fluoro-containing antireflective coatings was prepared by a sol–gel process the co-condensation of tetraethylorthosilicate and 1<italic>H</italic>,1<italic>H</italic>,2<italic>H</italic>,2<italic>H</italic>-perfluoroalkyltriethoxysilanes (POTS).
Gel/n-HA composite microspheres (VM) have shown successful therapeutic results in the treatment of osteomyelitis through targeted antibacterial, inflammatory regulation, osteoblast recruitment and bone regeneration characteristics.
Bone scaffolds offer hope for oral jawbone repair, yet improving their osteogenic performance remains a clinical challenge. This study investigates novel approach to enhance early bone formation and quality by coloading hydroxyapatite (HA)─internalized osteoblasts (OHA) osteonectin (ON) onto various scaffolds. Our findings demonstrated that the OHA could effectively facilitate regeneration providing rapid calcium phosphorus ion release via lysosome-mediated HA degradation, while ON protein...
A nano-hydroxyapatite/chitosan (n-HA/CS) scaffold loading with CS microspheres was developed in this study. First, an average diameter of ∼57 μm were prepared by cross-linking, and a three-dimensional (3D) printing technology used to fabricate n-HA/CS porous scaffolds pore size porosity 454 ± 51 60.71%, respectively. Then, the immersed solution cross-linked vanillin. The structure, porosity, composition, cellular behavior CS-microsphere-loaded investigated. In vitro cell experiments showed...
In this study, we aimed to improve the hydrophilicity, cellular activities and osteogenesis of polycaprolactone (PCL) scaffolds by adding gelatin (Gel) nano-hydroxyapatite (n-HA). We fabricated biocomposite using extrusion deposition 3 D printing method. The physical biological properties composite scaffold were evaluated. Scanning electron microscopy (SEM) revealed that Gel n-HA particles uniformly embedded in internal PCL. (PCL + n-HA) showed dramatically improved mechanical properties....
The present study focuses on the synthesis and evaluation of gelatin/nanohydroxyapatite (Gel/n-HA) composite microspheres fabricated by water-in-oil (W/O) emulsification process as potential substrates for bone repair applications. Herein, 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC)-crosslinked Gel/n-HA (10 wt%) were synthesized. morphology, physicochemical properties, cellular behavior EDC-crosslinked Gel-HA (ECM) characterized. In vitro cell culture assays demonstrated that ECM...