- Bone Tissue Engineering Materials
- Advanced materials and composites
- Diamond and Carbon-based Materials Research
- Carbon Nanotubes in Composites
- Orthopaedic implants and arthroplasty
- Electrospun Nanofibers in Biomedical Applications
- Aluminum Alloys Composites Properties
- Advanced ceramic materials synthesis
- High Entropy Alloys Studies
- biodegradable polymer synthesis and properties
- Graphene and Nanomaterials Applications
- MXene and MAX Phase Materials
- Graphene research and applications
- Metal and Thin Film Mechanics
- High-Temperature Coating Behaviors
- Ferroelectric and Piezoelectric Materials
- Dental Implant Techniques and Outcomes
- Advanced Surface Polishing Techniques
- Polymer Surface Interaction Studies
- Advanced Drug Delivery Systems
- Intermetallics and Advanced Alloy Properties
- Periodontal Regeneration and Treatments
- High-pressure geophysics and materials
- Advanced machining processes and optimization
- Magnesium Alloys: Properties and Applications
Case Western Reserve University
2024-2025
Sichuan University
2015-2024
Yanshan University
2014-2024
Analysis and Testing Centre
2016-2023
Chongqing University
2017-2022
Bridge University
2022
University of the West
2022
Huawei Technologies (China)
2022
Furtwangen University
2022
Université de Haute-Alsace
2022
To improve the mechanical properties of bone tissue and achieve desired regeneration for orthopedic surgery, newly designed hydroxyapatite/polyurethane (HA/PU) porous scaffolds were developed via in situ polymerization. The results showed that molecular modification PU soft segments by glyceride castor oil (GCO) can increase scaffold compressive strength 48% elastic modulus 96%. When nano-HA (n-HA) particles incorporated into GCO-PU matrix, further increased 49 74%, from 2.91 to 4.34 MPa 95...
The purpose of this study was to fabricate a low-immunogenicity fish collagen (FC) and bioactive nanohydroxyapatite (n-HA) enhanced poly(lactide-co-glycolide) (PLGA) nanofibrous membrane for guided bone regeneration (GBR) via electrospinning. physicochemical properties morphology revealed that FC n-HA particles were homogeneously dispersed in the PLGA fibrous matrix. Notably, formation polymeric chain network due interaction between significantly improved tensile strength membrane....
We demonstrate a simple, effective and feasible method to address the shrinkage of Poly (lactic-co-glycolic acid) (PLGA) through core-shell structure fiber strategy. The results revealed that introducing size-stable poly-caprolactone (PCL) as core significantly improved PLGA-based fibrous scaffold's dimensional maintenance. further utilized fish collagen modify PLGA shell layer (PFC) coaxial fibers loaded baicalin (BA) into PCL (PCL-BA) endow scaffold with more functional biological cues....
Abstract Despite extensive research on piezoelectric polymers since the discovery of poly(vinylidene fluoride) (PVDF) in 1969, fundamental physics polymer piezoelectricity has remained elusive. Based classic principle piezoelectricity, should originate from polar crystalline phase. Surprisingly, crystal contribution to strain coefficient d 31 is determined be less than 10%, primarily owing difficulty changing molecular bond lengths and angles. Instead, >85% Poisson's ratio, which closely...
Natural bone is a complex material with well-designed architecture. To achieve successful integration and regeneration, the constituent structure of bone-repairing scaffolds need to be functionalized synergistically based on biomimetics. In this study, hybrid membrane composed chitosan (CS), sodium carboxymethyl cellulose (CMC), nano-hydroxyapatite (n-HA) was curled in concentric manner generate an anisotropic spiral-cylindrical scaffold, compositional structural properties mimicking natural...
Notable differences exist between synthetic and native apatite in their crystal size state of existence bone tissue.
The study suggests a principle for future design and application of bone scaffolds that must have relatively stable osteogenic space scaffold interface, or degradation speed slower than the time reconstruction completion.
Multicomponent alloying has displayed extraordinary potential for producing exceptional structural and functional materials. However, the synthesis of single-phase, multi-principal covalent compounds remains a challenge. Here, we present diffusion-controlled strategy realization transition metal carbides (MPTMCs) with single face-centered cubic phase. The increased interfacial diffusion promoted by addition nonstoichiometric compound leads to rapid formation phase at much lower sintering...
The guided bone regeneration (GBR) concept has been extensively utilized to treat periodontal defects in clinical practice. However, the repair efficacy of currently available GBR membranes is often compromised by their limited alveolar potential, insufficient mechanical strength and inadequate space maintenance duration. In this paper, a novel hybrid bi-layer scaffold was fabricated using electrospun polycaprolactone/gelatine (PCL/Gel) nanofibre combined with 3D printed...
The ideal scaffold for bone repair should have a hierarchical pore structure and gradient degradation performance to satisfy the uniform adhesion proliferation of cells in at early stage implantation, as well providing space subsequent regeneration tissue.
Abstract Building of multifunctional coatings in a more effective way is crucial for meeting the multilevel requirements regenerative medicine. Herein, inspired by diatom and mussel, specific but universal approach proposed building on slow‐degradable fast‐degradable scaffolds or various substrates using epigallocatechin gallate (EGCG) polyethyleneimine (PEI) as bridges silicon coupling. The results reveal that polyphenol EGCG facilitates silica precipitation coating topological morphology...
In the study, a specific material system that contains poly-(ε-caprolactone) (PCL), polyvinyl acetate (PVAc) and hydroxyapatite (HA) was used to fabricate porous scaffolds employing 3D printing technique for bone regeneration. Four groups of were fabricated: PCL, PCL/PVAc, PCL/HA PCL/PVAc/HA comparision. The morphologies, mechanical properties biological characteristics these analyzed using SEM, testing machine, in vitro cell culture vivo animal experiments. results showed printed possessed...