A5071753555- Anesthesia and Pain Management
- Spine and Intervertebral Disc Pathology
- Shoulder Injury and Treatment
- Nerve Injury and Rehabilitation
- Musculoskeletal pain and rehabilitation
- Cardiac, Anesthesia and Surgical Outcomes
- Peripheral Nerve Disorders
- Pain Mechanisms and Treatments
- Nausea and vomiting management
- Pain Management and Treatment
- High Altitude and Hypoxia
- Orthopedic Surgery and Rehabilitation
- Neuroscience of respiration and sleep
- Airway Management and Intubation Techniques
- Hernia repair and management
- Clinical practice guidelines implementation
- Treatment of Major Depression
- Pelvic and Acetabular Injuries
- Botulinum Toxin and Related Neurological Disorders
- Pain Management and Opioid Use
- Intraocular Surgery and Lenses
- Ultrasound in Clinical Applications
- Trauma Management and Diagnosis
- Medical and Health Sciences Research
- Intraoperative Neuromonitoring and Anesthetic Effects
Universitätsklinik Balgrist
2017-2025
University of Zurich
2019-2024
Dentsply Sirona (United States)
2022
ZHAW Zurich University of Applied Sciences
2021
ETH Zurich
2020
Amt für Städtebau
2020
SR Research (Canada)
2020
Pain and Rehabilitation Medicine
2004-2019
University Hospital of Bern
2005-2018
Hirslanden Klinik St. Anna
2012-2015
Pulmonary hypertension is a hallmark of high-altitude pulmonary edema and may contribute to its pathogenesis. When administered by inhalation, nitric oxide, an endothelium-derived relaxing factor, attenuates the vasoconstriction produced short-term hypoxia.
<h3>Background and Objectives:</h3> Nerve blocks using local anesthetics are widely used. High volumes usually injected, which may predispose patients to associated adverse events. Introduction of ultrasound guidance facilitates the reduction volume, but minimal effective volume is unknown. In this study, we estimated 50% dose (ED<sub>50</sub>) 95% (ED<sub>95</sub>) 1% mepivacaine relative cross-sectional area nerve for an adequate sensory block. <h3>Methods:</h3> To reduce number healthy...
In Brief Recently, our study group demonstrated the usefulness of ultrasonographic guidance in ilioinguinal/iliohypogastric nerve blocks children. As a consequence, we designed follow-up to evaluate optimal volume local anesthetic for this regional technique. Using modified step-up-step-down approach, with 10 children each group, starting dose 0.2 mL/kg 0.25% levobupivacaine was administered perform an block under guidance. After patients, results were analyzed, and if all successful,...
In Brief BACKGROUND: Calcitonin was effective in a study of acute phantom limb pain, but it not studied the chronic phase. The overall literature on N-methyl-d-aspartate antagonists is equivocal. We tested hypothesis that calcitonin, ketamine, and their combination are treating pain. Our secondary aim to improve our understanding mechanisms action investigated drugs using quantitative sensory testing. METHODS: Twenty patients received, randomized, double-blind, crossover manner, 4 IV...
<h3>Background and Objectives</h3> The suprascapular nerve (SSN) block is frequently performed for different shoulder pain conditions perioperative postoperative control after surgery. Blind image-guided techniques have been described, all of which target the within supraspinous fossa or at notch. This classic point not always ideal when ultrasound (US) used because it located deep under muscles, hence visible. Blocking in supraclavicular region, where passes underneath omohyoid muscle,...
Background Chronic neck pain after whiplash injury is caused by cervical zygapophysial joints in 50% of patients. Diagnostic blocks nerves supplying the are performed using fluoroscopy. The authors' hypothesis was that third occipital nerve can be visualized and blocked with use an ultrasound-guided technique. Methods In 14 volunteers, authors placed a needle to on both sides neck. They punctured caudal perpendicular 14-MHz transducer. 11 0.9 ml either local anesthetic or normal saline...
<h3>Abstract</h3> The use of ultrasound in pain medicine for interventional axial, nonaxial, and musculoskeletal procedures is rapidly evolving growing. Because the lack specialty-specific guidelines ultrasonography medicine, an international collaborative effort consisting members Special Interest Group on Ultrasonography Pain Medicine from American Society Regional Anesthesia Medicine, European Anaesthesia Therapy, Asian Australasian Federation Societies developed following recommendations...
Chronic pain is associated with generalized hypersensitivity and impaired endogenous modulation (conditioned modulation; CPM). Despite extensive research, their prevalence in chronic patients unknown. This study investigated the potential determinants of widespread central described distribution CPM patients.We examined 464 consecutive for using pressure algometry at second toe cold pressor test. Potential were studied uni- multivariate regression analyses. Prevalence was calculated 5th,...
Background: Previous studies have shown that dexamethasone has a positive effect on postoperative pain control, opioid consumption, nausea, and vomiting length of hospital stay after arthroplasty surgery. Purpose/Hypothesis: The purpose this study was to assess whether adding perioperative our current regimen hip arthroscopy is more effective than placebo. It hypothesized would reduce pain, improve subjective nausea scores, the number events. Study Design: Randomized controlled trial; Level...
BACKGROUND Clinical practice in patients at risk of pulmonary aspiration varies widely. However, data on actual management, decision-driving factors and controversial issues remain elusive. OBJECTIVE We aimed to comprehensively review the management identify controversies among anaesthesia professionals. DESIGN National interprofessional survey. SETTING All departments Switzerland. PARTICIPANTS The survey was distributed electronically all members Swiss Society Anaesthesiology Perioperative...
According to previous studies, the addition of ketamine morphine for intravenous patient-controlled analgesia (PCA) may be beneficial. The authors developed and applied a new model optimize combination morphine, ketamine, lockout interval PCA after lumbar spine hip surgery.One-hundred two patients undergoing or surgery participated in study. analgesic effect during 48 h was optimized under restrictions dictated by side effects. Initially, eight combinations (expressed as drug concentration...
We tested the hypothesis that periodic breathing (PB) at high altitude is more frequent and arterial oxygen desaturation severe during sleep in subjects developing pulmonary edema (HAPE) or acute mountain sickness (AMS) compared with remaining healthy. registered thoraco-abdominal movement, electro-encephalogram saturation by pulse oximeter (pSao2) 21 first night spent of 4,559 m. During subsequent stay m, eight remained well (controls), five developed AMS HAPE. PB was found all stages...
Our study group recently evaluated an ED(95) local anaesthetic volume of 0.11 ml.mm(-2) cross-sectional nerve area for the ulnar nerve. This prospective, randomised, double-blind crossover investigated whether this is sufficient brachial plexus blocks at axillary level. Ten volunteers received ultrasonographic guided block either with ('low' volume) or 0.4 ('high' mepivacaine 1%. The mean (SD) was in low 4.0 (1.0) and 14.8 (3.8) ml high group. success rate individual 27 out 30 (90%) (100%),...
Cervical zygapophysial joint nerve blocks typically are performed with fluoroscopic needle guidance. Descriptions of ultrasound-guided block these nerves available, but only one small study compared ultrasound fluoroscopy, and for the third occipital nerve. To evaluate potential usefulness ultrasound-guidance in clinical practice, studies that determine accuracy this technique using a validated control essential. The aim was to cervical joints fluoroscopy as control.Sixty volunteers were...
In Brief BACKGROUND: The addition of ketamine to morphine for patient-controlled analgesia (PCA) is supported by previous basic and clinical research, but has been challenged subsequent negative studies. Important limitations studies are the low number patients analyzed, use morphine-ketamine combinations that may not optimal, all relevant outcomes have analyzed. this study, we compared combination with alone postoperative PCA in large patient groups. We used a identified an optimization...
Objective. A previous study of radiofrequency neurotomy the articular branches obturator nerve for hip joint pain produced modest results. Based on an anatomical and radiological study, we sought to define a potentially more effective method.