Precise manipulation of fluids and objects on the micro scale is seldom a simple task, but nevertheless crucial for many applications in life sciences chemical engineering. We present microfluidic chip fabricated silicon-glass, featuring one or several pairs acoustically excited sharp edges at side channels that drive pumping flow throughout produce strong mixing their vicinity. The simultaneously capable focusing cells microparticles are suspended flow. multifunctional micropump provides...

We numerically investigate the contribution of microstreaming to acoustic radiation force acting on a small elastic spherical particle placed into an ultrasonic standing wave. When wave scatters and appear as nonlinear time-averaged effects. The compressible Navier-Stokes equations are solved up second order in terms Mach number using finite element method. show that when viscous boundary layer thickness radius ratio is sufficiently large dense, dominates force. In this case, our theory...

Scattering of an acoustic wave by particles gives rise to microstreaming, as well radiation and interaction forces on the particles. We numerically study these steady, nonlinear phenomena for a case two elastic spheres in standing wave. show that if one or both are smaller comparable viscous boundary layer, microstreaming close pressure node can lead interparticle attraction along direction gradient Similar behavior is observed when, instead size, density sufficiently larger relative other...

In view of its influence on the acoustic radiation force, we investigate microstreaming around a small solid elastic particle in an ultrasonic standing wave dependence material properties and shape. The configuration is axisymmetric, making it accessible to numerical methods, such as finite element method. results reveal transition from viscous scattering- microstreaming-dominated force that depends density. When deviation shape sphere becomes smaller than boundary layer thickness, show...

Two-dimensional (2D) metal-particle focusing is an essential task for various fabrication processes. While acoustofluidic devices can manipulate particles in two-dimensions, the production of these often demands a cleanroom environment. Therefore, acoustically excited glass capillaries present cheap alternative to labor-intensive production. Here, we 2D metal microparticle round capillary using bulk acoustic waves. Excitation piezoelectric transducer at specific frequencies leads mode shapes...

Abstract

Sharp-edge structures exposed to acoustic fields are known produce a strong non-linear response, mainly in the form of streaming and radiation force. The two phenomena useful for various processes at microscale, such as fluid mixing, pumping, or trapping microparticles biological cells. Numerical simulations essential order improve performance sharp-edge-based devices. However, simulation sharp-edge scope whole acoustofluidic devices is challenging due thin viscous boundary layer that needs...

Abstract The acoustic contrast factor (ACF) is calculated from the relative density and compressibility differences between a fluid an object in fluid. To name but one application, knowing ACF of biological cell represents crucial step design acoustophoretic systems, for instance to isolate cancer cells liquid biopsy such as blood without labels or physical contact. For static different high frequency counterpart relevant ACF. In this study, we started by characterizing low vs. metastatic...

When an acoustic wave scatters on a particle the radiation force and microstreaming appear as non-linear time-averaged effects. Although they simultaneously, microstreaming, which is driven by viscous losses, often neglected in theoretical modeling of force. Here, we investigate contribution to acting small elastic spherical placed into ultrasonic standing [T. Baasch, A. Pavlic, J. Dual, Phys. Rev. E 100(6), 061102 (2019)]. The compressible Navier-Stokes equations are solved up second-order...

Precise manipulation of fluids and objects on the micro scale is seldom a simple task, but nevertheless crucial for many applications in life sciences chemical engineering. We present microfluidic chip fabricated silicon-glass, featuring one or several pairs acoustically excited sharp edges at side channels that drive pumping flow throughout produce strong mixing their vicinity. The simultaneously capable focusing cells microparticles are suspended flow. multifunctional micropump provides...

The acoustic contrast factor (ACF) is calculated from the relative density and compressibility differences between a fluid an object in fluid. To name but one application, this can be exploited using acoustophoretic systems to isolate cancer cells liquid biopsy, such as blood sample. Knowing ACF of cell represents crucial step design for purpose, potentially allowing isolation circulating without labels or contact. For biological static different high frequency counterpart relevant ACF. In...

Legionella are gram-negative, facultative intracellular, and pathogenic bacteria that pose a risk for human health cause significant energy losses due to extensive preventive heating-up of water installations. We investigate acoustically-driven motion - acoustophoresis several species, Escherichia coli, Pseudomonas aeruginosa, Acanthamoeba castellanii, common host in water. All the investigated cells can be acoustically manipulated an ultrasonic standing wave water, as they possess non-zero...

Two-dimensional metal particle focusing is an essential task for various fabrication processes. While acoustofluidic devices can manipulate particles in two dimensions, the production of these often demands a cleanroom environment. Therefore, acoustically excited glass capillaries present cheap alternative to labour-intensive production. Here, we 2D micro-particle round capillary using bulk acoustic waves. Excitation piezoelectric transducer at specific frequencies leads mode shapes...