Achieving controlled mobility of microparticles in viscous fluids can become pivotal biologics, biotechniques, and biomedical applications. The self-assembly, trapping, transport are being explored active matter, micro nanorobotics, microfluidics; however, little work has been done acoustics, particularly matter robotics. This study reports the discovery characterization microbubble behaviors a gel that is confined to slight opening between glass boundaries an acoustic field. Where incident...

Using the Lagrangian formalism, equations of radial and translational motions two coupled spherical gas bubbles have been derived up to terms third order in inverse distance between bubbles. The pulsations were then modified, for purpose allowing effects liquid compressibility, using Keller-Miksis' approach, translation added by viscous forces form Levich drag. This model was used a numerical investigation motion small, driven well below resonance, strong acoustic fields with pressure...

The acoustic radiation pressure exerted by a plane — progressive or standing sound wave on compressible sphere suspended freely in viscous fluid is calculated. In deriving the general expression for pressure, it supposed that radius of arbitrary. Two limiting cases interest are then considered. first these, assumed wavelength much larger than which is, turn, wavelength, being this condition satisfied both outside and inside sphere. second case, situation investigated when small compared with...

The acoustic radiation pressure exerted by an axisymmetric sound field on a rigid sphere suspended freely in viscous fluid is calculated, the being considered as having arbitrary radius relative to and wavelengths. limiting cases of special interest are then investigated, namely, force due plane progressive standing wave examined for when wavelength much more than both is, its turn, small or large compared with wavelength. It shown that influence viscosity surrounding can be quite...

Lipid-coated perfluorocarbon nanodroplets are submicrometer-diameter liquid-filled droplets with proposed applications in molecularly targeted therapeutics and ultrasound (US) imaging. Ultrasonic molecular imaging is unique that the optimal application of these agents depends not only on surface chemistry, but also applied US field, which can increase receptor-ligand binding membrane fusion. Theory experiments combined to demonstrate displacement nanoparticles direction propagation, where a...

There are numerous experimental investigations on sonoporation, while the theoretical background of this phenomenon still is in its infancy. One suggested mechanisms sonoporation linked to shear stress exerted cell membrane by acoustic microstreaming generated a contrast microbubble pulsating nearby cell. Currently, existing model effect based an equation that has been derived for free hemispherical bubble resting rigid plane. Such not adequate microbubble. In paper, improved theory assumes...

The acoustic radiation force exerted by an axisymmetric sound field on a spherical particle is calculated assuming that the surrounding fluid viscous and heat conducting. incident pressure amplitude supposed to be small enough such nonlinear effects like generation of subharmonics do not occur. No restrictions are imposed size, which means can arbitrary radius with respect sound, viscous, thermal wavelengths in fluid. obtained formula for general it applicable first, any field, as plane,...

The translational velocities of two spherical gas bubbles oscillating in water, which is irradiated by a high-intensity acoustic wave field, are calculated. assumed to be located far enough apart so that shape oscillations can neglected. Viscous effects included owing the small size bubbles. An asymptotic solution obtained accounts for viscous drag on each bubble, large bar. Numerical simulations show forces between tend attractive, except narrow region bubble corresponding nonlinear...

The expression for the mutual interaction force between two pulsating gas bubbles immersed in an incompressible and inviscid fluid is derived assuming that distance comparable to their sizes. results of numerical calculations air water are presented. They show at small distances substantially different from given by Bjerknes’ theory [Fields Force (Columbia University Press, New York, 1906)] which separation assumed be large comparison with bubble discrepancy seems result effect multiple...

Using the Lagrangian formalism, coupled equations of radial and translational motions a spherical gas bubble in an acoustic wave field are derived. The equation motion is then modified, for purpose allowing effects liquid compressibility, using Keller–Miksis’ approach, translation added by primary Bjerknes force viscous form Levich drag. resulting solved numerically studying plane standing wave. It shown that, if pressure amplitude high enough, driven below resonance, instead moving to...

The present paper proposes a model that describes the encapsulation of microbubble contrast agents by linear Maxwell constitutive equation. also incorporates translational motion agent microbubbles and takes into account radiation losses due to compressibility surrounding liquid. To establish physical features proposed model, comparative analysis is performed between this two existing models, one which treats as viscoelastic solid following Kelvin-Voigt equation other assumes encapsulating...

The problem of acoustic microstreaming that develops around a gas bubble in an ultrasound field is considered. It shown the solutions obtained previously by Wu and Du [(1997). J. Acoust. Soc. Am. 101, 1899–1907], which are based on assumption viscous effects essential only within thin boundary layer while beyond liquid can be considered to inviscid, lead severe underestimation power streaming. An improved theory suggested corrects errors previous extends its limits. proposed treats entire...

Interest in the problem under consideration this study is motivated by targeted ultrasound imaging where one has to deal with microbubble contrast agents pulsating near blood vessel walls. A modified Rayleigh–Plesset equation derived that describes oscillation of a agent an elastic wall finite thickness. It assumed medium behind fluid but it shown obtained easily transformable case solid. In model rigid wall, which predicts decreasing natural frequency bubble reveals can both decrease and...

Perfluorocarbon (PFC) microdroplets, called phase-change contrast agents (PCCAs), are a promising tool in ultrasound imaging and therapy. Interest PCCAs is motivated by the fact that they can be triggered to transition from liquid state gas an externally applied acoustic pulse. This property opens up new approaches applications medicine. Insight into physics of vaporization PFC droplets vital for effective use anticipating bioeffects. composed volatile PFCs (with low boiling point) exhibit...

Surface acoustic waves are shown to be powerful tools control translation and rotation of single particles in microfluidic devices.

We study sharp-edge structures that are used in microfluidic systems for particle and cell manipulation. Experiments show oscillating sharp edges can attract or repel particles suspended a channel. This effect is caused by acoustic radiation forces induced edges. propose an analytical theory allows one to evaluate the force produced structure on elastic which parameters govern interaction of with structure, forcing them be attracted situation repelled another situation. The proposed gives...

An analytical theory is developed that describes acoustic microstreaming produced by the interaction of an oscillating gas bubble with a viscoelastic particle. The assumed to undergo axisymmetric oscillation modes, which can include radial oscillation, translation and shape modes. oscillations particle are excited bubble. No restrictions imposed on ratio radii viscous penetration depth separation distance, as well distance. Capabilities illustrated computational examples. shear stress...

An analytical theory is developed that describes acoustic microstreaming produced by the interaction of an oscillating gas bubble with a viscoelastic particle. The assumed to undergo axisymmetric oscillation modes, which can include radial oscillation, translation and shape modes. oscillations particle are excited bubble. No restrictions imposed on ratio radii viscous penetration depth separation distance, as well distance. Capabilities illustrated computational examples. shear stress...

Using the Lagrangian formalism, coupled equations are derived that describe radial and translational motions of an arbitrary bubble in a three-dimensional cluster subject to ultrasound field. The obtained incorporate nonlinear coupling volume modes bubbles as well interactions between all up terms third order inverse separation distances. Solving these for each multibubble structure, consisting N with spatial arrangement, collective dynamics this structure can be simulated. potentialities...

This paper studies the nonlinear coupling between volume pulsation, translational motion and shape modes of an oscillating bubble, especially in context instability, known as 'dancing motion', that is demonstrated by bubbles acoustic standing waves. A set coupled equations derived describes pulsations a its oscillations evolving on bubble surface. The amplitudes surface velocity are assumed to be small allowed for up only second-order terms. amplitude oscillation not limited. Unlike earlier...