A5100609028- Suicide and Self-Harm Studies
- Functional Brain Connectivity Studies
- Mental Health Research Topics
- Tryptophan and brain disorders
- Child and Adolescent Psychosocial and Emotional Development
- Treatment of Major Depression
- Attention Deficit Hyperactivity Disorder
- Healthcare professionals’ stress and burnout
- Stress Responses and Cortisol
- COVID-19 and Mental Health
- Nicotinic Acetylcholine Receptors Study
- Obsessive-Compulsive Spectrum Disorders
- Traumatic Brain Injury Research
- Bipolar Disorder and Treatment
- Maternal Mental Health During Pregnancy and Postpartum
- Posttraumatic Stress Disorder Research
- Eating Disorders and Behaviors
- Advanced Neuroimaging Techniques and Applications
- Psychosomatic Disorders and Their Treatments
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Electroconvulsive Therapy Studies
- Neural dynamics and brain function
- Neuroinflammation and Neurodegeneration Mechanisms
- Mental Health Treatment and Access
- Transcranial Magnetic Stimulation Studies
The Affiliated Yongchuan Hospital of Chongqing Medical University
2013-2025
Chongqing Medical University
2016-2025
Boston University
2024
University of California, Davis
2024
Zhongda Hospital Southeast University
2023
Second Xiangya Hospital of Central South University
2023
Central South University
2023
Dongfeng General Hospital
2022
Knowledge Unlatched (Germany)
2020
Affiliated Hospital of Southwest Medical University
2019
During an epidemic of a novel infectious disease, frontline nurses suffer from unprecedented psychological stress. This study aimed to assess the immediate impact on in China.A multicenter, cross-sectional survey was conducted via online questionnaires. Symptoms depression, anxiety, somatic disorders, and suicidal ideation were evaluated. Demographic, stress, support variables entered into logistic regression analysis identify factors.Of 4,692 who completed survey, 9.4% (n = 442) considered...
Background: Non-suicidal self-injury (NSSI), which commonly occurs during adolescence, often co-occurs with major depressive disorder (MDD). However, the underlying neurobiological mechanisms in adolescents MDD who engage NSSI remain unclear. The current study examined aberrant local neural activity certain areas of visual regions and default mode network (DMN) resting-state functional connectivity (rs-FC) changed brain only. Methods: A total 67 were divided into two groups based on their...
Major depressive disorder (MDD) seriously endangers adolescent mental and physical health. Extracellular vesicles (EVs) are mediators of cellular communication involved in many physiological brain processes. Although EV miRNAshave been implicated adults with major psychiatric disorders, investigation into their effects MDDremains scarce. In discovery set, we conducted a genome-wide miRNA sequencing serum EVs from 9 untreated adolescents MDD 8 matched healthy controls (HCs), identifying 32...
Major depressive disorder (MDD) is one of the most widespread mental disorders and can result in suicide. Suicidal ideation (SI) strongly predictive death by suicide, electroconvulsive therapy (ECT) effective for MDD, especially patients with SI. In present study, we aimed to determine differences resting-state functional magnetic resonance imaging (rs-fMRI) 14 adolescents aged 12-17 MDD SI at baseline after ECT. All participants were administered Hamilton Depression Scale (HAMD) Beck...
Maresin-1 is an antiphlogistic agonist synthesized by macrophages from docosahexaenoic acid (DHA). It has both anti-inflammatory and pro-inflammatory properties been found to enhance neuroprotection cognitive function. However, there limited knowledge of its effects on depression the potential mechanism remains unclear. In this study, lipopolysaccharide (LPS)-induced depressive symptoms neuroinflammation were investigated in mice possible cellular molecular mechanisms further clarified....
Previous studies in small samples have identified inconsistent cortical abnormalities major depressive disorder (MDD). Despite genetic influences on MDD and the brain, it is unclear how risk for translated into spatially patterned vulnerability. Here, we initially examined voxel-wise differences function structure using largest multi-modal MRI data from 1660 patients 1341 controls. Combined with Allen Human Brain Atlas, then adopted transcription-neuroimaging spatial correlation newly...
Internet addiction (IA) is common among young students. This study aimed to examine the influence and mechanisms of IA susceptible personality traits on impact suicidal ideation in adolescent students China.This cross-sectional (09/2012-09/2015) used stratified cluster sampling with "school type" for stratification; 136,266 from 63 schools completed questionnaire. Logistic regression analysis was performed estimate effect (Young's Addiction Test) (Barratt impulsiveness scale, Buss & Perry...
Background & aim The coronavirus disease 2019 (COVID-19) pandemic has affected the life and work of people worldwide. present study aimed to evaluate rhythm disruptions life, work, entertainment, their associations with psychological impacts during initial phase COVID-19 pandemic. Method A cross-sectional was conducted from 10 th 17 March 2020 in China. structured e-questionnaire containing general information, Chinese version Brief Social Rhythm Scale, Zung’s self-rating scales...
Major depression is a serious and chronic mental illness. However, its etiology poorly understood. Although glial cells have been increasingly implicated in the pathogenesis of depression, specific role microglia astrocytes stress-induced remains unclear. Translocator protein (TSPO) has long considered marker neuroinflammation microglial activation. this also present on astrocytes. Thus, it necessary to explore relationships between TSPO, microglia, context depression. In study, C57BL/6J...
Major depressive disorder (MDD) is a disabling and severe psychiatric with high rate of prevalence, adolescence one the most probable periods for first onset. The neurobiological mechanism underlying adolescent MDD remains unexplored.In this study, we examined cortical subcortical alterations neuroanatomical structures spontaneous functional activation in 50 unmedicated adolescents vs. 39 healthy controls through combined structural resting-state magnetic resonance imaging.Significantly...
The consumption of takeaways is becoming increasingly prevalent. Despite this, the relationship between takeaway food and depressive symptoms in Chinese populations has not been clarified. Furthermore, factors that mediate association frequency are unknown. Questionnaires were employed to collect data from 6,417 new students at Chongqing Medical University autumn 2023, including sociodemographic information, frequency, physical activity levels (measured by International Physical Activity...