A5101570109- Functional Brain Connectivity Studies
- Attention Deficit Hyperactivity Disorder
- Suicide and Self-Harm Studies
- Child and Adolescent Psychosocial and Emotional Development
- Impact of Technology on Adolescents
- Advanced Neuroimaging Techniques and Applications
- Child Abuse and Trauma
- Neural dynamics and brain function
- Transcranial Magnetic Stimulation Studies
- Child and Adolescent Health
- Migration, Health and Trauma
- Advanced MRI Techniques and Applications
- Stress Responses and Cortisol
- Retinal and Optic Conditions
- Histone Deacetylase Inhibitors Research
- Exercise and Physiological Responses
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Homelessness and Social Issues
- Retinal and Macular Surgery
- Bioinformatics and Genomic Networks
- Historical Psychiatry and Medical Practices
- Insect-Plant Interactions and Control
- Neurology and Historical Studies
- Machine Learning in Bioinformatics
- Lymphoma Diagnosis and Treatment
Shenzhen KangNing Hospital
2018-2024
Jinzhou Kangning Hospital
2018-2024
Ningbo Science and Technology Bureau
2023
Shenzhen University
2020
Huadong Hospital
2017
Fudan University
2017
Second Military Medical University
2015
Changhai Hospital
2015
Yunnan Environmental Protection Bureau
2008
Abstract Despite a growing neuroimaging literature on the pathophysiology of major depressive disorder (MDD), reproducible findings are lacking, probably reflecting mostly small sample sizes and heterogeneity in analytic approaches. To address these issues, Depression Imaging REsearch ConsorTium (DIRECT) was launched. The REST-meta-MDD project, pooling 2428 functional brain images processed with standardized pipeline across all participating sites, has been first effort from DIRECT. In this...
To assess the influence of region interest (ROI) on tumor apparent diffusion coefficient (ADC) measurements and interobserver variability in pancreatic ductal adenocarcinoma (PDAC).Twenty-two patients recruited with pathology-proven PDAC underwent diffusion-weighted imaging (DWI, 3.0T) prior to surgical resection. Two independent readers measured ADCs according three ROI methods: whole-volume, single-slice, small solid sample tumor. Minimum mean were obtained. The for each methods was...
Previous studies in small samples have identified inconsistent cortical abnormalities major depressive disorder (MDD). Despite genetic influences on MDD and the brain, it is unclear how risk for translated into spatially patterned vulnerability. Here, we initially examined voxel-wise differences function structure using largest multi-modal MRI data from 1660 patients 1341 controls. Combined with Allen Human Brain Atlas, then adopted transcription-neuroimaging spatial correlation newly...
This study aimed to explore the effect of maternal exposure cumulative childhood trauma (CT) on offspring CT and depressive symptoms. A total 3672 mothers their adolescent who completed questionnaires were included in this study. was assessed using Childhood Trauma Questionnaire Short Form, while symptoms adolescents Center for Epidemiological Studies Depression Scale. Among respondents, 1397 (38.04%) reported ever having experienced 463 (12.61%) ≥ 2 types CT. As shown by logistic regression...
Associations between attention deficit hyperactivity disorder (ADHD) subtypes and suicidal behaviors remains unclear. The current study explored the prevalence of behaviors, its association with ADHD among Chinese medical students.Five thousand six hundred ninety-three college students participated. Symptoms ADHD, anxiety, depression, tobacco alcohol use were assessed using online questionnaires.The lifetime ideation, suicide plans, attempts 27.5, 7.9 14.8% respectively. Participants...
Extranodal nasal-type natural killer/T-cell lymphoma (NKTCL) is an Epstein-Barr virus (EBV)-associated with a strong tendency relapse or be refractory in response to chemotherapy. Development of new strategy for NKTCL treatment still quite necessary. In this study, we found that aspirin suppresses VEGF expression SNK-6 cells. Further investigation showed increases histone methylation the range -100~0 proximal transcription start site on promoter, subsequently decreasing binding ability Sp1...
Abstract Schizophrenia and autism spectrum disorders (ASD) were considered as two neurodevelopmental had shared clinical features. we hypothesized that they have some common atypical brain functions the purpose of this study was to explored spontaneous activity strength alterations in early onset schizophrenia (EOS) ASD children adolescents with a multi-center large-sample study. A total 171 EOS patients (aged 14.25 ± 1.87), 188 9.52 5.13), 107 healthy controls 11.52 2.82) scanned...
It has been demonstrated that childhood maltreatment (CM) is associated with an increased risk of depression and psychotic symptoms. However, there still a lack studies on the prevalence co-occurring severe symptoms (CSDPS) association between CM CSDPS among college students.
Background: The subgenual anterior cingulate cortex (sgACC) plays a central role in the pathophysiology of major depressive disorder (MDD), and its functional interactive profile with left dorsal lateral prefrontal (DLPFC) is associated transcranial magnetic stimulation (TMS) treatment outcomes. Nevertheless, previous research on sgACC connectivity (FC) MDD has yielded inconsistent results, partly due to small sample sizes limited statistical power. Furthermore, calculating sgACC-FC target...
Early-onset schizophrenia (EOS) and autism spectrum disorder (ASD) are two mental disorders with abnormal neurodevelopment overlapping clinical symptoms. However, few prospective multi-center imaging studies explored their pathophysiological differences similarities comprehensively. We utilized a large cohort of functional magnetic resonance data standardized scanning protocols from 594 participants (276 high-functioning ASD, 187 EOS, 131 normal controls (NCs)) recruited at five centers. A...
Background Non-suicidal self-injury (NSSI) is a worldwide mental health problem that deserves thorough investigation. This study aims to explore the effect of parenting styles, attachment parents, and self-compassion on occurrence non-suicidal behavior in adolescents whether these factors influence their recovery motivation. Methods A total 132 who had engaged NSSI within last year 72 never were recruited from Shenzhen Kangning Hospital primary secondary schools communities. Differences...
Childhood trauma (CT) can lead to long-term psychiatric disturbances. The current study investigated the prevalence of CT and its associated risk factors among Chinese adolescents with disorders. Adolescents were recruited from a large on mental health in Hunan province China 2014. had two-phase cross-sectional design. Patients disorders (n = 907) healthy subjects 2,240) completed Trauma Questionnaire–Short Form. Of all types CT, emotional neglect (EN; 48.44%-68.82%) physical (PN;...