- Functional Brain Connectivity Studies
- Child and Adolescent Psychosocial and Emotional Development
- Mental Health Research Topics
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Personality Disorders and Psychopathology
- Psychosomatic Disorders and Their Treatments
- Advanced Neuroimaging Techniques and Applications
- Neural and Behavioral Psychology Studies
- Stress Responses and Cortisol
- Neural dynamics and brain function
- Resilience and Mental Health
- Attention Deficit Hyperactivity Disorder
- Child Abuse and Trauma
- Advanced MRI Techniques and Applications
- Schizophrenia research and treatment
- EEG and Brain-Computer Interfaces
- Personality Traits and Psychology
- Psychosocial Factors Impacting Youth
- Suicide and Self-Harm Studies
- Early Childhood Education and Development
- Psychotherapy Techniques and Applications
- Neurotransmitter Receptor Influence on Behavior
- Mental Health and Psychiatry
- Cognitive Abilities and Testing
- Cultural Differences and Values
Second Xiangya Hospital of Central South University
2016-2025
Central South University
2016-2025
National Clinical Research Center for Digestive Diseases
2020-2024
National Clinical Research
2020
Shanghai International Studies University
2017
McLean Hospital
2016
Harvard University
2016
Creative Commons
2016
National Institutes of Health
2000-2016
Auerbach Associates (United States)
2016
Major depressive disorder (MDD) is common and disabling, but its neuropathophysiology remains unclear. Most studies of functional brain networks in MDD have had limited statistical power data analysis approaches varied widely. The REST-meta-MDD Project resting-state fMRI (R-fMRI) addresses these issues. Twenty-five research groups China established the Consortium by contributing R-fMRI from 1,300 patients with 1,128 normal controls (NCs). Data were preprocessed locally a standardized...
The expectation that Chinese people present distress somatically is a central prediction of cultural psychopathology and has been the subject considerable theoretical speculation. At same time, empirical studies have infrequent yielded mixed results. authors examined symptom presentation in (n=175) Euro-Canadian (n=107) outpatients, using spontaneous problem report, structured clinical interview, questionnaire methods. All 3 methods cross-culturally equivalent somatic psychological...
Major depressive disorder (MDD) is a globally prevalent and highly disabling disease characterized by dysfunction of large-scale brain networks. Previous studies have found that static functional connectivity not sufficient to reflect the complicated time-varying properties brain. The underlying dynamic interactions between networks MDD remain largely unknown, it also unclear whether neuroimaging-based are sufficiently robust discriminate individuals with from healthy controls since...
Some environmental stressors lead to the onset of depression via inhibiting hippocampal BDNF expression, but other stressors-induced exhibits no change in expression. The underlying mechanisms behind divergence remain unknown. In this study, depression-like behaviors were induced rats by maternal deprivation (MD) and chronic unpredictable stress (CUPS). Depression-like tested open field test, forced swimming sucrose consumption test. miR-16 expressions hippocampus examined real-time PCR. MD...
The primary aim was to examine the depressive symptom structure of Mainland China adolescents using Center for Epidemiologic Studies Depression Scale (CES-D).Exploratory factor analysis (EFA) and confirmatory (CFA) were simultaneously conducted determine CES-D in a large scale, representative adolescent samples recruited from China. Multigroup CFA (N = 5059, 48% boys, mean 16.55±1.06) utilized test factorial invariance structure, which generated by EFA confirmed across gender.The can be...
Abstract The aim of the present study was to develop a Chinese version Cognitive Emotion Regulation Questionnaire (CERQ-C) and examine its psychometric properties in sample university students. English translated back-translated prior administration 791 participants recruited from two universities Changsha, Hunan (China). Internal consistency, test–retest reliability, inter-scale factorial validity were analysed. CERQ-C exhibited: (1) moderate internal consistency (Cronbach's α=.83); (2)...
Major depressive disorder (MDD) is known to be characterized by altered brain functional connectivity (FC) patterns. However, whether and how the features of dynamic FC would change in patients with MDD are unclear. In this study, we aimed characterize using a large multi-site sample novel network-based approach. Resting-state magnetic resonance imaging (fMRI) data were acquired from total 460 473 healthy controls, as part REST-meta-MDD consortium. networks constructed for each subject...
Major depressive disorder (MDD) is heterogeneous associated with aberrant functional connectivity within the default mode network (DMN). This study focused on data-driven identification and validation of potential DMN-pattern-based MDD subtypes to parse heterogeneity disorder. The sample comprised 1397 participants including 690 patients 707 healthy controls (HC) registered from multiple sites based REST-meta-MDD Project in China. Baseline resting-state magnetic resonance imaging (rs-fMRI)...
Abstract Despite a growing neuroimaging literature on the pathophysiology of major depressive disorder (MDD), reproducible findings are lacking, probably reflecting mostly small sample sizes and heterogeneity in analytic approaches. To address these issues, Depression Imaging REsearch ConsorTium (DIRECT) was launched. The REST-meta-MDD project, pooling 2428 functional brain images processed with standardized pipeline across all participating sites, has been first effort from DIRECT. In this...
The Revised NEO Personality Inventory (NEO-PI-R) is a measure of the 5-factor model developed on volunteer samples in United States. To examine its validity non-Western, psychiatric sample, an existing Chinese translation was modified for use People's Republic China (PRC). instrument administered to 2,000 in- and outpatients at 13 sites throughout PRC. Internal consistency low some facet scales, but retest reliability adequate hypothesized factor structure clearly recovered. Correlations...
The current study examined the psychometric properties of Chinese translation Barratt Impulsiveness Scale 11th version in a sample adolescents from Hunan province, mainland China. During an initial assessment, 396 secondary school students (Grades 10–12) completed scale and self-report measures assessing problem behaviors alcohol use. was re-administered 1 mo. later. Analysis gave Cronbach alpha .80 test-retest reliability .70. Confirmatory factor analysis indicated model containing six...
ORIGINAL RESEARCH article Front. Psychol., 27 June 2013Sec. Cultural Psychology Volume 4 - 2013 | https://doi.org/10.3389/fpsyg.2013.00377
Most studies have shown that insecure attachment and stress are important risk factors in the development of depression anxiety. However, it is unclear whether distinct patterns may relate differently to anxiety following stressful events. Thus, current study examined anxious avoidant attachment, both which operationalized as predict depressive symptoms occurrence hassles.A sample 662 Chinese university students was recruited from Hunan, China. At initial assessment, participants completed...