A5055605331- Seaweed-derived Bioactive Compounds
- Marine and coastal plant biology
- Marine Sponges and Natural Products
- Parasites and Host Interactions
- Echinoderm biology and ecology
- Parasite Biology and Host Interactions
- Cephalopods and Marine Biology
- Marine Biology and Ecology Research
- Selenium in Biological Systems
- Biocrusts and Microbial Ecology
- Sulfur Compounds in Biology
- Nanoparticles: synthesis and applications
- Aquaculture Nutrition and Growth
- Bone Tissue Engineering Materials
- Graphene and Nanomaterials Applications
- Marine and Coastal Ecosystems
- Aquatic Ecosystems and Phytoplankton Dynamics
- Marine Bivalve and Aquaculture Studies
- Protein Hydrolysis and Bioactive Peptides
- Organoselenium and organotellurium chemistry
- Helminth infection and control
- Algal biology and biofuel production
Universidade de São Paulo
2011-2022
Instituto de Botânica
2011
Two known sesquiterpenes (1R*,2S*,3R*,5S*,8S*,9R*)-2,3,5,9-tetramethyltricyclo[6.3.0.0(1,5)]undecan-2-ol and (1S*,2S*,3S*,5S*,8S*,9S*)-2,3,5,9-tetramethyltricyclo-[6.3.0.0(1,5)]undecan-2-ol were isolated for the first time from essential oil of red seaweed Laurencia dendroidea collected in Brazilian coast. These compounds not active against eight bacteria strains yeast Candida albicans, but showed some antioxidant activity. Both also found other species showing that they are exclusive...
In Brazil, the Laurencia complex is represented by twenty taxa: s.s. with twelve species, Palisada four species (including Chondrophycus furcatus now that proposal of its transference to in process), and Osmundea Yuzurua two each. The majority Brazilian have been phylogenetically analyzed 54 rbcL sequences, including five other Rhodomelacean as outgroups. analysis showed monophyletic high posterior probability value. was separated into clades, corresponding genera: Chondrophycus, Laurencia,...
We present an environment friendly synthesis of selenium nanoparticles and the study their cytotoxic activity against uterine sarcoma cancer fibroblasts cells.Amorphous (a-SeNPs) trigonal (t-SeNPs) were synthesized using D-fructose as reducing agent characterized by high-resolution transmission electron microscopy (HRTEM), energydispersive X-ray spectroscopy (EDX), powder diffraction analysis (XRD), inductively coupled plasma optical emission spectrometry (ICP OES), dynamic light scattering...
The resistance of pathogens to commonly used antibiotics has enhanced morbidity and mortality triggered the search for new drugs. Several species red alga genus Laurencia are very interesting candidates as potential sources natural products with pharmaceutical activity because they known produce a wide range chemically halogenated secondary metabolites. This is an initial report antifungal activities metabolites five Laurencia, collected in state Espírito Santo, against three strains...
The development of new anti-cancer drugs algal origin represents one the least explored frontiers in medicinal chemistry. In this regard, diversity micro- and macroalgae found Brazilian coastal waters can be viewed as a largely untapped natural resource. report, we describe comparative study on cytotoxic properties extracts obtained from Laurencia complex: aldingensis, L. catarinensis, dendroidea, intricata, translucida, sp, Palisada flagellifera. All these species were collected State...
ABSTRACT In current study, we report efficient and clean procedure for preparing mycosporine‐like amino acids (MMAs) analogs evaluate their ultraviolet absorbance properties antioxidant activities. The radiation patterns of the compounds were recorded then used to define molar absorptivities. activities assessed using 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) radical scavenging superoxide assays. Eight nine showed good activity against radicals, as only one exhibited a measurable IC 50 in DPPH...
Schistosomiasis may be caused by six different species of the genus Schistosoma. Current treatment is based only on two drugs: oxamniquine, which effective against Schistosoma mansoni species, and praziquantel, ineffective young parasites. Therefore, research new drugs their targets for this disease urgently needed. In present work, efficacies several seaweeds extracts S. were tested. Worm couples incubated with concentration seaweed 120 h monitored after first 2 then every 24 to evaluate...
Schistosomiasis is a parasitic disease that affects more than 250 million people. The treatment limited to praziquantel and the control of intermediate host with highly toxic molluscicidal niclosamide. Marine algae are poorly explored promising alternative can provide lead compounds, use multivariate analysis could contribute quicker discovery. As part our search for new natural compounds which schistosomiasis, we screened 45 crude extracts obtained from 37 Brazilian seaweed species their...
An ongoing phycological survey of the Laurencia complex in Mexican Caribbean revealed an undescribed species belonging to Chondrophycus. The new exhibits vegetative and reproductive structures typical genus, except for presence a slightly compressed thallus, translucent outermost cortical cell layer with conspicuous wall projections, tetrasporangia produced from particular formation one additional fertile periaxial cell. phylogenetic position this taxon was inferred based on...
Schistosomiasis has been controlled for more than 40 years with a single drug, praziquantel, and only one molluscicide, niclosamide, raising concern of the possibility emergence resistant strains. However, molecular targets both agents are thus far unknown. Consequently, search lead compounds from natural sources encouraged due to their diverse structure function. Our potential use in schistosomiasis control led identification an algal species,
Macroalgae are considered bioindicators for marine pollution, because they have the ability to quickly react changes in their environment. In consequence, macroalgae populations fluctuate, according species characteristics and adaptive strategies. Their cell wall polysaccharides contain sulfate groups that capable of retaining accumulating heavy metals. addition traditional contaminants, emerging pollutants being recognized aquatic environments. Herein, been identified after desorbed from...