Ulugbek Zakirovich Mirkhodjaev

ORCID: 0000-0002-3334-8295
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About
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Research Areas
  • Flame retardant materials and properties
  • Polymer crystallization and properties
  • Natural Fiber Reinforced Composites
  • Polymer Nanocomposites and Properties
  • Molecular Sensors and Ion Detection
  • Lysosomal Storage Disorders Research
  • Pesticide Exposure and Toxicity
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Autophagy in Disease and Therapy
  • Analytical Chemistry and Sensors
  • Parkinson's Disease Mechanisms and Treatments
  • Adenosine and Purinergic Signaling
  • Hereditary Neurological Disorders
  • Advanced Chemical Sensor Technologies
  • Genetic Neurodegenerative Diseases
  • Toxic Organic Pollutants Impact
  • Neurological diseases and metabolism
  • Glycogen Storage Diseases and Myoclonus
  • Silicone and Siloxane Chemistry
  • Combustion and Detonation Processes
  • Ion channel regulation and function
  • Mass Spectrometry Techniques and Applications
  • Agriculture, Plant Science, Crop Management

National University of Uzbekistan
2004-2025

Parkinson's disease (PD) is a progressive neurodegenerative disorder induced by the loss of dopaminergic neurons in midbrain. The mechanism neurodegeneration associated with aggregation misfolded proteins, oxidative stress, and mitochondrial dysfunction. Considering this, process removal unwanted organelles or proteins autophagy vitally important neurons, activation these processes could be protective PD. Short-time acidification cytosol can activate mitophagy autophagy. Here, we used sodium...

10.1111/febs.16198 article EN cc-by FEBS Journal 2021-09-16

Polyurethane (PUR), as an engineering polymer, is widely used in many sectors of industries. However, the high fire risks associated with PUR, including smoke density, a heat release rate, and toxicity combustion products limit its applications fields. This paper presents influence silsesquioxane fillers, alone synergistic system halogen-free flame-retardant compounds, on reducing hazard polyurethane foams. The flammability PUR composites was determined use pyrolysis flow calorimeter (PCFC)...

10.3390/polym16050645 article EN Polymers 2024-02-27

Due to growing restrictions on the use of halogenated flame retardant compounds, there is great research interest in development fillers that do not emit toxic compounds during thermal decomposition. Polymeric composite materials with reduced flammability are increasingly demand. Here, we demonstrate unmodified graphene and carbon nanotubes as well basalt fibers or flakes can act effective retardants polymer composites. We also investigate effects mixtures these mineral thermal, mechanical,...

10.3390/ma14185245 article EN Materials 2021-09-12

The aim of the research was to investigate influence calcium phosphinate (HPCA) and aluminum (HPAL) in synergistic systems with organophosphorus compounds, i.e., diphenylcresyl phosphate (CDP) trichloropropyl (TCPP), on thermal stability, flammability, smoke density, emission toxic gases during decomposition polyurethane (PUR) foams. Thermogravimetric analysis (TGA), along cone calorimetry microcalorimetry, were used assess fillers stability flammability PUR gas products performed use a...

10.3390/ma17143517 article EN Materials 2024-07-16

Carbon black commonly found in elastomeric composites is the main precursor of smoke formed during thermal decomposition and combustion these materials. It has been proven that soot particles suspended air, absorbing carcinogenic, mutagenic teratogenic, organic compounds from groups dioxins, furans polyaromatic hydrocarbons, penetrating into living organisms through respiratory tract, pose a serious threat to human health life. Therefore, it proved this paper, partial replacement carbon with...

10.1016/j.polymertesting.2022.107900 article EN cc-by-nc-nd Polymer Testing 2022-12-11

The smoke emitted during thermal decomposition of elastomeric composites contains a significant number carcinogenic and mutagenic compounds from the group polycyclic aromatic hydrocarbons, PAHs, as well polychlorinated dibenzo-p-dioxins furans, PCDDs/Fs. By replacing carbon black with specific amount lignocellulose filler, we noticeably reduced fire hazard caused by composites. filler parameters associated flammability tested composites, decreased emission, limited toxicity gaseous products...

10.3390/polym15081975 article EN Polymers 2023-04-21
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