A5025421695- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Bacterial Infections and Vaccines
- COVID-19 Impact on Reproduction
- Antibiotic Resistance in Bacteria
- Long-Term Effects of COVID-19
- Pneumonia and Respiratory Infections
- COVID-19 and Mental Health
- COVID-19 and healthcare impacts
- Infectious Encephalopathies and Encephalitis
- Nosocomial Infections in ICU
- Herpesvirus Infections and Treatments
- Vaccine Coverage and Hesitancy
- Extracellular vesicles in disease
- Hepatitis Viruses Studies and Epidemiology
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- SARS-CoV-2 detection and testing
- Infectious Diseases and Tuberculosis
- Urinary Tract Infections Management
- Inflammatory Biomarkers in Disease Prognosis
- Poxvirus research and outbreaks
- Orthopedic Infections and Treatments
- Inflammasome and immune disorders
- Neutropenia and Cancer Infections
Hamad Medical Corporation
2017-2025
Development Fund
2022
University Hospitals Coventry and Warwickshire NHS Trust
2022
Hamad General Hospital
2008-2018
Qatar Airways (Qatar)
2013
Abstract Tocilizumab, an interleukin‐6 inhibitor, may ameliorate the inflammatory manifestations associated with severe coronavirus disease 2019 (COVID‐19) and thus improve clinical outcomes. This was a retrospective review of patients laboratory‐confirmed COVID‐19 who received tocilizumab completed 14 days follow up. Twenty‐five were included, median age 58 years (interquartile range, 50‐63) majority males (92%). Co‐morbidities included diabetes mellitus (48%), chronic kidney (16%),...
There are limited data on Coronavirus Disease 2019 (COVID-19) outcomes at a national level, and none after 60 days of follow up. The aim this study was to describe national, 60-day all-cause mortality associated with COVID-19, identify risk factors admission an intensive care unit (ICU).
BackgroundCentral nervous system (CNS) viral infections are an important cause of morbidity and mortality. No data available regarding their epidemiology in Qatar.DesignWe retrospectively evaluated all cerebrospinal fluid findings from January 2011–March 2015 at Hamad Medical Corporation. Those with abnormal CSF finding were included our study. We excluded those missing medical records, no clinical evidence CNS infection, or proven bacterial, fungal tuberculosis infection. classified as...
There is a lack of predictive markers for early and rapid identification disease progression in COVID-19 patients. Our study aims at identifying microRNAs (miRNAs)/small nucleolar RNAs (snoRNAs) as potential biomarkers severity. Using differential expression analysis microarray data (n = 29), we identified hsa-miR-1246, ACA40, hsa-miR-4532, hsa-miR-145-5p, ACA18 the top five differentially expressed transcripts severe versus asymptomatic, hsa-miR-3609, ENSG00000212378 (SNORD78),...
Preventing local transmission of malaria from imported cases is crucial for achieving and maintaining elimination. This study aimed to investigate the epidemiological characteristics assess distribution vectors in Qatar. Data January 2016 December 2022 on malaria, including demographic characteristics, travel-related information, diagnostic results, were collected analysed using descriptive statistics. Field surveys conducted 2021-22 mosquitoes various traps across The samples underwent...
Background In March 2020, the rapid spread of SARS-CoV-2 prompted global vaccination campaigns to mitigate COVID-19 disease severity and mortality. The 2-dose BNT162b2-mRNA vaccine effectively reduced infection mortality rates, however, waning effectiveness necessitated introduction a third dose or booster. Aim To assess magnitude longevity booster-induced immunity, we conducted longitudinal study specific cellular humoral immune responses among Qatar’s vulnerable craft manual worker...
To estimate the real-world effectiveness of sotrovimab against severe, critical, or fatal COVID-19 in Qatar at a time which most SARS-CoV-2 incidences occurred due to BA.2 Omicron subvariant.We conducted matched case-control study among all individuals eligible for treatment per United States Food and Drug Administration guidelines resident population Qatar. The odds progression severe forms were compared cases (treatment group) versus controls (eligible patients who opted not receive...
Coronavirus disease-2019 (COVID-19) was declared as a pandemic by WHO in March 2020. SARS-CoV-2 causes wide range of illness from asymptomatic to life-threatening. There is an essential need identify biomarkers predict disease severity and mortality during the earlier stages disease, aiding treatment allocation resources improve survival. The aim this study at time SARS-COV-2 infection patients high risk developing severe associated with low survival using blood parameters, including...
Background and Objectives . Bacterial meningitis is a common medical condition in Qatar. The aim of this study was to describe the clinical characteristics bacterial meningitis, frequency each pathogen, its sensitivity antibiotics risk factors for death. Patients Methods This retrospective conducted at Hamad General Hospital between January 1, 2009, December 31, 2013. Results We identified 117 episodes acute 110 patients. Their mean age was<mml:math...
ObjectiveThis study examined the initial impact of a national BNT162b2 vaccine rollout on SARS-CoV-2 infections in Qatar.MethodsAll individuals who had completed ≥14 days follow-up by 16 March 2021 after receiving were included. This calculated incidence rates (IR) and their 95% confidence intervals (CI) during 1–7, 8–14, 15–21, 22–28, >28 post-vaccination. Poisson regression was used to calculate rate ratios (IRR) relative first 7-day post-vaccination period.ResultsA total 199,219 with...
BACKGROUND:Primary pituitary tuberculosis (in absence of other organ involvement and constitutional symptoms) is an extremely rare disease with total reported cases in the literature fewer than a hundred. Misdiagnosis as adenoma common late diagnosis can result permanent endocrine dysfunction and/or long-term neurologic sequelae. CASE REPORT:We report on case middle-aged woman who presented severe headache left third cranial nerve palsy. Magnetic resonance imaging (MRI) revealed large tumor...
Case series of Rapidly growing Mycobacterial Post-operative wound infection with Mycobacterium Abscessus and/or Chelone in 4 cases kidney transplant adult recipient who presented within 6 months transplant.We report Renal recipients post-surgical site NTM-69-year-old microbiologically proven discontinued treatment and further intra-abdominal abscess. Next case was 61 years male nodular swellings at surgical US findings muscle abscess tested culture positive for Chelonae Abscessus.Third 34...
To describe the clinical presentation, underlying diseases, antimicrobial susceptibility, treatment and outcome of Klebsiella pneumoniae meningitis patients. This retrospective study involved all patients with 15 years age or older who admitted to Hamad General Hospital culture proven from January 1, 2007 December 31, 2012. A total ten cases were identified (nine males one female). Their mean was (43.3±12.8) years. Eight (80%) had nosocomial neurosurgery being most frequent associated...
We report four cases of nosocomial E. coli meningitis, in male patients with accidental and neurosurgical trauma. The interval between accidents/neurosurgical procedures the onset meningitis was 2-15 days (mean 6.25 days). most consistent clinical features were fever deterioration consciousness level. Emergence extended spectrum beta lactamase strains had been observed two (50%) our mean duration antimicrobial treatment 16.5 (range: 6-24 Two died hospital.
Abstract Effectiveness of sotrovimab against severe, critical, or fatal COVID-19 was investigated in Qatar using a case-control study design at time when BA.2 Omicron subvariant dominated incidence. Adjusted odds ratio progression to COVID-19, comparing those sotrovimab-treated untreated, 2.67-fold higher (95% CI: 0.60-11.91).
Abstract Background There are limited data on Coronavirus Disease 2019 (COVID-19) outcomes at a national level, and none after 60 days of follow up. The aim this study was to describe national, 60-day all-cause mortality associated with COVID-19, identify risk factors admission an intensive care unit (ICU). Methods This retrospective cohort including the first consecutive 5000 patients COVID-19 in Qatar who completed up by June 17, 2020. Outcomes included diagnosis, for ICU. Results Included...
Children are particularly vulnerable to the psychological effects of COVID-19 pandemic. The disruption in daily life has impacted children significantly. Moreover, increased worrying associated with probability getting infected or becoming seriously unwell due infection can potentially precipitate anxiety disorders among children.This study aimed determine rates elevated symptoms infection. It also explored whether there were any differences terms age, gender, and residency status.A...
Objective To establish the impact of smoking on severity COVID-19 infection among adults 18 years and above in Qatar during 2020–2021.Design Analytical cross-sectional study from May 2020 to 2021.Setting Health Information System (HIS) Communicable disease control center Hamad Medical Corporation Qatar.Participant We randomly selected participants all confirmed cases (n = 1036). Participants below old, people with HIV, those who could not communicate English Arabic were excluded. The...
Abstract Objective We herein report the initial impact of a national BNT162b2 rollout on SARS-CoV-2 infections in Qatar. Methods included all individuals who by 16 March 2021 had completed ≥14 days follow up after receipt BNT162b2. calculated incidence rates (IR) and their 95% confidence intervals (CI), during 1–7, 8–14, 15–21, 22–28, >28 post-vaccination. Poisson regression was used to calculate rate ratios (IRR) relative first 7-day post-vaccination period. Results 199,219 with...