A5034498796- Leptospirosis research and findings
- Muscle and Compartmental Disorders
- Hormonal and reproductive studies
- Sexual Differentiation and Disorders
- Biomarkers in Disease Mechanisms
- HIV-related health complications and treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Influenza Virus Research Studies
- Pharmacological Effects and Toxicity Studies
- Vector-borne infectious diseases
- HIV/AIDS drug development and treatment
- Venous Thromboembolism Diagnosis and Management
- Acute Kidney Injury Research
- Neurological Complications and Syndromes
- Mosquito-borne diseases and control
Universidade Federal do Ceará
2018-2023
Background: The aim of this study was to investigate factors associated with poor outcomes among elderly hospitalized patients leptospirosis.Methods: This is a retrospective cohort leptospirosis admitted three tertiary hospitals in Fortaleza, Brazil, from January 1985 July 2017. Patients were divided into two groups: (age ≥60 years) and young <60 years). A comparison demographical, clinical laboratory data, treatment executed order differences between groups.Results: total 507 included, mean...
To investigate the prediction ability of vascular injury biomarkers for haemodialysis requirement in patients with severe leptospirosis.Prospective study leptospirosis hospitalised Fortaleza, Brazil. Blood samples were collected hospital admission to quantify biomarkers: syndecan-1, ICAM-1, VCAM-1, angiopoietin-2 and FGF-23. Two groups evaluated according during stay.Twenty-seven included, a mean age 39 ± 18 years. 88.9% males. 53.8% needed presented higher levels on syndecan-1 (572...
Leptospirosis is a globally distributed zoonosis with broad clinical spectrum. This disease mostly affects liver and kidney tissues. Other organs such as the pancreas, can be affected by leptospirosis-induced vasculitis. In addition, cardiac manifestations are common, presence of transient ECG abnormalities found in 70% patients. We report male patient who presented an atypical leptospirosis that progressed severe acute pancreatitis, injury atrial fibrillation. Early diagnosis adequate...
The excessive chase for beauty standards and the rise of muscle dysmorphia have ultimately led to an increase in androgenic–anabolic steroids (AAS) intramuscular injections vitamins A, D E (ADE) abuse, which is associated with several adverse effects has become a public health issue. This review literature discusses kidney injury use AAS ADE, highlighting mechanisms acute chronic renal lesion, such as direct toxicity, glomerular hyperfiltration hypercalcemia. Future perspectives regarding...
This study aimed to investigate the association between novel biomarkers and renal injury in people with HIV (PWH). A cohort was carried out PWH under chronic use of antiretroviral therapy (ART), followed at a public outpatient service. Clinical laboratory parameters patients were evaluated year by year, from 2015 [at baseline (year 1, Y1)] 2019 [year 5 (Y5)]. At baseline, damage (e.g., neutrophil gelatinase-associated lipocalin-NGAL, monocyte chemoattractant protein-1-MCP-1, kidney...
Abstract Background and Aims Hyponatremia is associated with severe complication in tropical diseases may be higher mortality. The aim of this study was to investigate the association between hyponatremia disease severity patients leptospirosis. Method This a retrospective including confirmed diagnosis leptospirosis admitted three reference hospitals Fortaleza, northeast Brazil, period from 1985 2018. Demographic, clinical laboratory data were analyzed, incidence unfavorable outcomes...
HIV-infected patients are at high risk for developing critical diseases, including opportunistic infections (OI), with consequent admission in intensive care units (ICU). Renal disfunctions factors death HIV/AIDS patients, and survival rates undergoing hemodialysis smaller than the ones observed general population. In this context, study aimed to investigate death-related an setting. This is a retrospective cross-sectional performed through analysis of medical records from 271...
INTRODUCTION AND AIMS: Evaluate application of Bioimpedance (BIA) in acute kidny injury (AKI) prognosis.Implication phase angle (PA), nutritional and volemic parameters.METHODS: We include a cohort 180 patients (me ´dium age 66 years SD 1.2, male 73.3 %) with AKI corporal BIA evaluate bioelectrical parameters (PA) cellular membrane integrity), Extracellular/intracellular water ratio (ECW/ICW) extracellular edema), muscle/fat mass (M/F) celular idex (CMI) status, clinical prognostic index...
Abstract Background and Aims Leptospirosis has a broad clinical spectrum. Many patients present severe disease, with potentially fatal outcomes. Novel biomarkers of endothelial activation are being studied in order to predict the severity disease establish early assistance patients. Method For analysis biomarkers, blood samples were collected at hospital admission, proper material for serum isolation. Aliquots frozen -80 ºC until was done. To quantify ELISA kits used: Syndecan-1...
Over the last years much research has been carried out, especially after influenza pandemic in 2009. It is known that many strains of virus are widely spread global population causing seasonal outbreaks every year. Influenza leads to flu-like symptoms, which present favorable prognosis, since most patients completely recover from it within two five days. Many new antiviral drugs have developed few years, but infection generally presents a mild course, symptom-based care often enough. can...