- Leptospirosis research and findings
- Acute Kidney Injury Research
- Muscle and Compartmental Disorders
- Dialysis and Renal Disease Management
- Research on Leishmaniasis Studies
- Viral Infections and Vectors
- Parasites and Host Interactions
- Mosquito-borne diseases and control
- Venomous Animal Envenomation and Studies
- Renal Diseases and Glomerulopathies
- Hemoglobinopathies and Related Disorders
- COVID-19 Clinical Research Studies
- Chronic Kidney Disease and Diabetes
- Rabies epidemiology and control
- Liver Disease and Transplantation
- Renal and Vascular Pathologies
- Iron Metabolism and Disorders
- Renal function and acid-base balance
- Malaria Research and Control
- Pneumocystis jirovecii pneumonia detection and treatment
- Leprosy Research and Treatment
- Kidney Stones and Urolithiasis Treatments
- Tuberculosis Research and Epidemiology
- Pediatric Urology and Nephrology Studies
- Trypanosoma species research and implications
Universidade Federal do Ceará
2015-2024
Hospital Universitário Walter Cantídio
2010-2021
Universidade de Fortaleza
2012-2020
Hospital Geral de Fortaleza
2004-2020
Universidade Federal do Rio Grande do Sul
2014
Universidade de São Paulo
1992-2013
Hospital César Milstein
2013
National Council for Scientific and Technological Development
2011-2012
Ministry of Science, Technology and Innovation
2011
Ministry of Education
2011
The risk factors for death and changes in clinical patterns leptospirosis (Weil's disease) have not been well studied. We retrospectively studied 110 patients with Weil's disease hospitalized Brazil between 1985 1996. Univariate statistical analysis showed that nonsurvivors were older than survivors, had higher frequency of oliguria, cardiac arrhythmia, dyspnea, pulmonary rales. Logistic regression the only independent factor associated was oliguria (odds ratio [OR] = 8.98). presence...
Introduction. The aim of this study is to evaluate the risk factors for acute kidney injury (AKI) and 30-day mortality after liver transplantation. Material methods. This a retrospective cohort consecutive adults undergoing orthotopic transplantation (OLT) at referral hospital in Brazil, from January 2013 2014. Risk AKI death were investigated. Results. A total 134 patients included, with median age 56 years. was found 46.7% first 72 h OLT. were: viral hepatitis (OR 2.9, 95% CI = 1.2-7),...
Summary Objectives To identify the main clinical and laboratory features of disseminated histoplasmosis (DH) in human immunodeficiency virus (HIV) patients compare them with those HIV other opportunistic diseases. Methods Retrospective study comparing data without DH. Univariate multivariate analyses were performed to verify risk factors related Results In total, 378 included, 164 DH 214 Acute renal failure, respiratory insufficiency septic shock more frequent patients, who also had a higher...
Background: Acute kidney injury (AKI) is an uncommon but serious complication after trauma.The objective of this study was to evaluate the prevalence, clinical characteristics and outcome AKI trauma.Patients Methods: This a retrospective performed from January 2006 2008 in emergency specialized hospital Fortaleza city, northeast Brazil.All patients with admitted period were included.Prevalence AKI, investigated.Results: Of 129 intensive care unit (ICU), 52 had AKI.The mean age 30.1 ± 19.2...
A leptospirose é a zoonose mais importante do mundo. Os pacientes são tipicamente homens jovens. Vários fatores estão envolvidos na insuficiência renal aguda (IRA) leptospirose, incluindo ação nefrotóxica direta da leptospira, hiperbilirrubinemia, rabdomiólise e hipovolemia. principais achados histológicos nefrite intersticial necrose tubular aguda. IRA geralmente não oligúrica hipocalêmica. Alterações função precedem queda taxa de filtração glomerular, o que poderia explicar alta frequência...
Techniques with high sensitivity and specificity are required for an accurate diagnosis in low-transmission settings, where the conventional parasitological methods insensitive. We determined accuracy of up-converting phosphor-lateral flow circulating anodic antigen (UCP-LF CAA) assay urine serum Schistosoma mansoni low-prevalence settings Ceará, Brazil, before after praziquantel treatment. Clinical samples a total 258 individuals were investigated by UCP-LF CAA, point-of-care - cathodic...
Acute kidney injury (AKI) following snakebite is common in developing countries and Bothrops genus the main group of snakes Latin America. To evaluate pathogenic mechanisms associated with venom nephrotoxicity, we assessed urinary blood samples patients after hospital admission resulting from a prospective cohort study Northeast Brazil. Urinary were evaluated during stay 63 consenting patients, divided into AKI No-AKI groups according to KDIGO criteria. The showed higher levels MCP-1...
Acute coronary syndromes are associated with a high prevalence of complications including heart failure (HF). The aim this study was to investigate the association novel biomarkers occurrence post-acute myocardial infarction (AMI) HF. A prospective conducted patients admitted emergency department ST-segment elevation (STEMI). Blood and urine samples were collected for analysis traditional biomarkers, interleukin-6, vascular cell adhesion molecule 1 (VCAM-1), intercellular molecule-1...
Leptospirosis is a zoonosis of worldwide importance. The disease endemic in Brazil. This study was conducted to describe the clinical and laboratory presentation leptospirosis metropolitan city retrospective including 201 consecutive patients with admitted tertiary hospitals Fortaleza, Brazil, between 1985 2006. All had epidemiological data suggestive leptospirosis, positive laboratorial test for (microscopic agglutination test, MAT, higher than 1:800). A total were included, mean age 38.9 ±...