- Venomous Animal Envenomation and Studies
- Rabies epidemiology and control
- COVID-19 Clinical Research Studies
- Poisoning and overdose treatments
- Healthcare and Venom Research
- Sepsis Diagnosis and Treatment
- Mosquito-borne diseases and control
- Bioactive Natural Diterpenoids Research
- Traumatic Ocular and Foreign Body Injuries
- Muscle and Compartmental Disorders
- Climate Change and Health Impacts
- Heavy Metal Exposure and Toxicity
- Forensic Entomology and Diptera Studies
- Pancreatitis Pathology and Treatment
- Research on Leishmaniasis Studies
- Environmental and biological studies
- Pesticide Exposure and Toxicity
- Respiratory Support and Mechanisms
- Acute Kidney Injury Research
- Drug-Induced Hepatotoxicity and Protection
- Phytochemistry Medicinal Plant Applications
- Methemoglobinemia and Tumor Lysis Syndrome
- Intensive Care Unit Cognitive Disorders
- Viral Infections and Outbreaks Research
- Viral Infections and Vectors
Universidade de Fortaleza
2019-2024
Hospital Geral de Fortaleza
2009-2023
Universidade Federal do Ceará
2009-2023
Rio Branco Institute
2022
Hospital Universitário Walter Cantídio
2010
Acute kidney injury (AKI) following snakebite is common in developing countries and Bothrops genus the main group of snakes Latin America. To evaluate pathogenic mechanisms associated with venom nephrotoxicity, we assessed urinary blood samples patients after hospital admission resulting from a prospective cohort study Northeast Brazil. Urinary were evaluated during stay 63 consenting patients, divided into AKI No-AKI groups according to KDIGO criteria. The showed higher levels MCP-1...
Abstract Aim Acute kidney injury ( AKI ) is one of the main causes morbidity and mortality in cases envenomation by venomous snakes. The present study was carried out to investigate clinical laboratory manifestations accidents with snakes risk factors associated these accidents. Methods A retrospective patients victims snakebite admitted a reference centre. defined according RIFLE AKIN criteria. Results total 276 were included, which 230 (83.7%) males. observed 42 (15.2%). mean genus...
Visceral leishmaniasis (VL) is endemic in Brazil and appears to occur epidemic form the state of Ceará. Few epidemiologic studies have been done on VL this state. The aim study establish pattern Fortaleza City show how urbanization has occurred recent years.Data were obtained from State Health Department Fortaleza, Ceará, included all cases registered January 2001 December 2006.There a marked increase an elevated incidence urban areas. Children young people most affected group.The occurrence...
SUMMARY The aim of this study was to describe the epidemiological profile snakebite accidents reported by toxicological assistance center in Fortaleza, Ceará, Brazil. Database information on analyzed regarding period from January 2003 December 2011. A total 1063 cases were found. occurred during rainy months (March, April and May), urban areas (52.3%), affecting individuals younger than 50 years predominantly among males (70.7%). lower limbs most frequently affected body area (33.7%). Most...
Objetivo: descrever casos de tentativa suicídio por exposição a agentes tóxicos
Loxoscelism is a clinical condition involving spiders of the genus Loxosceles. One most severe complications acute kidney injury (AKI). This study aimed to investigate AKI and other associated with loxoscelism.We analyzed cases diagnosed loxoscelism in an area where accidents were caused by Loxosceles amazonica from January 2010 December 2015. was defined according KDIGO criteria.Forty-five patients recorded: 95.6% presented characteristic necrotic skin lesions 13.3% AKI.Loxoscelism could...
Bothrops erythromelas are serpents that belong to the Viperidae family, which main species responsible for human snakebites in Ceara State, Northeast Brazil. Thrombotic microangiopathy (TMA) is an uncommon group of disorders characterized by microangiopathic hemolytic anemia (MAHA), thrombocytopenia and acute kidney injury (AKI), occurrence after have been rarely reported. In this report, we described case a 57 year-old-man without comorbidities who was bitten on his right ankle. He...
The Simplified Acute Physiology Score (SAPS) 3 is a reliable score to predict mortality. This study aims investigate the predictive values of SAPS and other clinical parameters for death in critically ill coronavirus disease 2019 (COVID-19) patients.This prospective tertiary hospital patients who required intensive care due COVID-19 infection northeast Brazil. Two distinct groups were constructed according epidemiological data: first wave second wave. severity admitted was estimated using...
Aim: To evaluate the prediction capacity of urinary biomarkers for death in critically ill patients with COVID-19. Methods: This is a prospective study due to COVID-19 infection. The NGAL, KIM-1, MCP-1 and nephrin were quantified on ICU admission. Results: There was 40% death. Urinary had no association Tubular (proteinuria, NGAL KIM-1) predictors cut-off values them useful stratify worse prognosis. In multivariate cox regression analysis, only remains associated two-mount survival chance....
The COVID-19 pandemic has challenged the entire world, and patients with diabetes mellitus (DM) have been particularly affected. We aimed to evaluate predictors of mortality during first 30 days hospitalization in critically ill comorbid DM. This prospective study included 110 admitted infection. Thirty-two (29%) had a previous diagnosis Clinical variables, laboratory tests, vascular biomarkers, such as VCAM-1, syndecan-1, ICAM-1, angiopoietin-1, angiopoeitin-2, were evaluated after...
In the past decades, an epidemic of chronic kidney disease (CKD) has been associated with environmental and occupational factors (heat stress from high workloads in hot temperatures exposure to chemicals, such as pesticides metals), which termed CKD non-traditional origin (CKDnt). This descriptive review aims present recent evidence about heat stress, pesticides, metals possible causes CKDnt provide overview related Brazilian regulation, enforcement, health surveillance strategies. workers...
Objective: To assess whether the use of ELMO, a helmet for noninvasive ventilation created in Brazil, had positive impact on prognosis patients with hypoxemic respiratory failure caused by severe COVID-19. Methods: This is retrospective study 50 critically ill COVID-19 patients. Epidemiological, clinical, and laboratory data were collected ICU admission, as well before, during, after ELMO use. Patients divided into two groups (success failure) according to outcome. Results: improved...
Pheochromocytoma is a rare disease charactrized by excessive production of catecholamines, manifestating mainly with hypertension. We report the case 45-year-old woman history sudden onset dyspnea, headache, palpitations and sudoresis. An abdominal ultrasound was suggestive chronic kidney (CKD). computed tomography magnetic resonance performed showed mass in topography left adrenal. The patient underwent surgery for removal became stable normal blood pressure levels, but remained CKD....
Resumo Nas últimas décadas, uma epidemia de doença renal crônica (DRC) tem sido associada a fatores ambientais e ocupacionais (estresse térmico decorrente cargas trabalho elevadas em altas temperaturas exposição produtos químicos, como agrotóxicos metais), denominada DRC origem não tradicional (DRCnt). Esta revisão descritiva objetivo apresentar evidências recentes sobre estresse térmico, metais possíveis causas DRCnt fornecer visão geral das estratégias brasileiras regulamentação,...
The clinical picture of coronavirus disease 2019 (COVID-19)-associated sepsis is similar to that other aetiologies. present study aims analyse the role syndecan-1 (SDC-1) as a potential predictor septic shock in critically ill patients with COVID-19.