Guo Lu

ORCID: 0000-0002-3365-4874
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About
Contact & Profiles
Research Areas
  • Cerebrovascular and Carotid Artery Diseases
  • Acute Ischemic Stroke Management
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Stroke Rehabilitation and Recovery
  • Extracellular vesicles in disease
  • Neurological and metabolic disorders
  • S100 Proteins and Annexins
  • Pediatric health and respiratory diseases
  • MicroRNA in disease regulation
  • Alzheimer's disease research and treatments
  • Acute Myeloid Leukemia Research

Dezhou University
2018-2020

Yancheng First People's Hospital
2020

Nantong University
2020

Background and purpose MicroRNAs (miRNAs) have been demonstrated to play crucial roles in the early stage of acute ischaemic stroke (AIS). The this study was investigate expression patterns miRNAs peripheral blood mononuclear cells (PBMCs) from AIS patients further explore related molecular mechanisms stroke‐induced immunodeficiency syndrome (SIDS). Methods miRNA PBMCs were detected by microarray validated quantitative real‐time polymerase chain reaction (qRT‐PCR) healthy controls....

10.1111/ene.14282 article EN European Journal of Neurology 2020-04-27

Alzheimer's disease (AD) is the most common cause of dementia. Despite numerous studies on subject, pathologies for AD are still unclear and there no ideal biomarker diagnosis. The present study aimed to investigate clinical significance human complement factor H (CFH) in patients with late-onset AD.The prospective included 187 who went our hospital from January 2015 December 2017. One hundred mild cognitive impairment (MCI) 80 healthy individuals were age gender matched enrolled as...

10.1590/0004-282x20190151 article EN cc-by Arquivos de Neuro-Psiquiatria 2020-01-31

Postural treatment for acute cerebral infarction involves supine position, lateral position and head elevation. In recent decades, controversy arises concerning determination between Head elevation may decrease intracranial pressure reduce incidence of pneumonia while strengthen perfusion improve oxygenation indexes in the area to promote recanalization. There has been no clear clinical evidence determine best or rehabilitation patients with infarction. This article, hoping provide...

10.3760/cma.j.issn.1671-8925.2018.05.022 article EN Chinese Journal of Neuromedicine 2018-05-15

Abstract Background One-third of acute ischaemic stroke (AIS) occurs in patients with an abnormal glucose metabolism, but little is known the differences glycemic variations (GV) between and without metabolism. The objective this study was to observe GV AIS T2D using continuous monitoring (CGM). Methods This a multi-center, prospective, observational performed March 2018 September 5 hospitals China. After admission, all recruited were subjected consecutive 4-day CGM. At endpoint, divided...

10.21203/rs.3.rs-17611/v1 preprint EN cc-by Research Square (Research Square) 2020-03-18
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