Subclinical Vitamin B12 deficiency is a very common entity in the Indian subcontinent with devastating clinical and socio-economic consequences. The objective of this study was to estimate proportion vitamin deficient children evaluate their profile.This prospective analytical conducted tertiary level care institute Northern India.Children pallor, were included study. Detailed history, height, weight percentiles characteristic features recorded complete blood counts, mean corpuscular volume...

Brain abscesses are uncommon in neonates. Klebsiella pneumoniae is a very microbial agent to cause brain abscess. We report 2 infants with sepsis who developed abscesses. One infant was premature neonate required mechanical ventilation for respiratory distress syndrome and subsequently nosocomial abscess without evidence of preceding meningitis. Another full-term risk factors seizures on the sixth postnatal day found have meningitis Both had septicemia multiple relatively large that...

Background: Exchange transfusion (ET) for hyperbilirubinemia is associated with many complications. The complications are underreported as most of the published studies retrospective, used varying definitions adverse events (AEs) and variable follow-up periods. Aim: We evaluated incidence clinical, biochemical, hematological, radiological AEs, including serious within 2 weeks ET in neonates, using standard definitions. Materials Methods: This prospective observational study was conducted...

Urinary tract infection (UTI) in children is one of the commonest bacterial infections seen pediatric population. Clinical presentation ranges from fever with or without focus and isolation microbiological agents streamline treatment. Moreover, local/regional microbial profiles are helpful antibiotic selection, we conducted a study to assess prevalence urine culture positivity suspected case UTI. In addition, susceptibility patterns ultrasonography (USG) finding culture-positive patients...

This case-control study was conducted to identify maternal and placental risk factors of small-for-gestational-age (SGA) fetal malnutrition.Cases comprised 104 consecutively delivered SGA neonates (determined as per INTERGROWTH- 21st standard). An equal number next-born gestation gender-matched appropriatefor- gestational age (AGA) served controls. Maternal were enquired, placentae evaluated by clinical histopathological examination. Nutrition the assessed assessment nutrition (CAN) score....

International Journal of Case Reports and Images (IJCRI)International (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas basic medical sciences clinical specialties.Aim IJCRI to encourage the publication new information by providing a platform for reporting unique, unusual rare cases which enhance understanding disease process, its diagnosis, management clinico-pathologic correlations.

International Journal of Case Reports and Images (IJCRI)International (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas basic medical sciences clinical specialties.Aim IJCRI to encourage the publication new information by providing a platform for reporting unique, unusual rare cases which enhance understanding disease process, its diagnosis, management clinico-pathologic correlations.

Background: Rhesus incompatibility is a preventable cause for severe neonatal hyperbilirubinemia, hydrops fetalis and still births. The prevalence of the Rh-negative blood group among Indian woman varies from 2% - 10%. Despite declining incidence incompatibility, due to availability anti-D immunoglobulin, improved antenatal care pregnant woman, it accounts significant proportion hyperbilirubinemia neuro-morbidity. women having Rh-positive neonates 60%. Objectives: This study aimed estimate...

In nephrotic syndrome (NS) due to podocytopathies, loss of vitamin D binding globulin along with albumin in urine leads Vitamin deficient state. We aimed study the severity deficiency and its clinical correlation children NS. performed a cross-sectional at tertiary care hospital Northern India. Enrolment aged 1–18 years was done. Patient's detailed history, numbers relapse, treatment details, data regarding various immunomodulatory drugs treatment. level estimated, status further classified...

Developmental delay (DD) is an important long-term neuromorbidity owing to various insults the developing brain and neuroimaging plays a key role in evaluating these children. Magnetic resonance spectroscopy (MRS) only noninvasive method determine levels of metabolites which aids delineating underlying abnormalities. A total 48 children aged between 6 months years with developmental were included evaluated our study. Sensitivity MRS DD plus (DD along seizures, abnormal motor findings,...

Introduction: Neonatal hypocalcemia (NH) is a common metabolic complication in neonates, more so premature and high risk neonates. It classified as early late neonatal hypocalcemia. Early NH occurs the first 24–48 hours of life while observed at end week. Vitamin D deficiency an important cause for hypocalcemic seizures developing countries. High rate skeletal growth coupled with low vitamin

Metachromatic leukodystrophy is a rare disorder of myelin metabolism. This degenerative results from the accumulation cerebroside sulfatide within sheath central and peripheral nervous system, due to deficiency aryl sulfatase A enzyme. We report 5-year-old male child, who presented with regression milestones, recurrent seizures spasticity second year life. Initially neurodegenerative was considered case investigated neuroimaging enzyme levels. Computed tomography (CT) brain showed...

BACKGROUND: Congenital rubella syndrome (CRS) is the second leading cause of nontraumatic childhood cataracts in India.While nuclear cataract most common abnormality reported CRS, congenital glaucoma a rarer manifestation.CASE REPORT: A 34weeks low birth weight, male neonate was born by vaginal delivery with normal APGARS.The had sparse hypo pigmented hair over scalp, along hypopigmented eye brows and lashes.There were erythematous lesions palms, soles groin region.Eye examination revealed...

Transient abnormal myelopoiesis (TAM) is a hematological disorder, which rare but unique for children with Down syndrome. It important to diagnose this entity, as these are at 500 times higher risk the development of acute myeloid leukemia (AML) later in life. We report late-preterm, low birth weight, female baby born 35-year-old G4P2L2A1 mother. The was diagnosed have down’s phenotype birth. On day one life, had leukocytosis increased peripheral blast cells. 23rd there resolution and...

Objective: Precordial catch syndrome was described by Miller and Texidor in 1955. It deserves wider recognition because it is rarely discussed the differential diagnosis of precordial pain. Case summary: characteristics include a young 8-year-old female that presented with 4th episode chest pain to hospital. On attempting maneuver like deep breaths slowly lying down position, subsided within 5 minutes although all other modalities investigation as electrocardiography, echocardiography,...

Introduction: Myoclonic-astatic epilepsy of early childhood (MAE)/Doose syndrome (DS) is an infrequent entity causing myoclonic-astatic seizures. Case Report: A 2-year-old male child presenting with history seizures from one year, inability to speak and choreiform movements. He had isolated speech delay other quadrants being normal (speaks monosyllables at two years). Parents noticed brief jerky movements both upper lower limbs increasing intensity over 2–3 months which became a daily...

A BSTRACT Background: Urinary tract infection (UTI) is a common in children with nephrotic syndrome (NS). Clinical experience suggests that childhood frequently diagnosed incorrectly and managed inadequately on the top of this existing UTI episode becomes an additive obstacle for primary care physicians or pediatricians towards optimum management, leading to poor outcome. So, we have conducted clinico- microbiological study NS provide exact picture so providers can be helped having high...

Haemophilia is one of the bleeding disorders, which inherited, in an xlinked recessive pattern. The diagnosis by estimation factor levels 8 and 9. Timebound treatment for people living with (PWH) replacement during manifestation. prevalence was mostly underestimated, it more so hilly terrains like state Uttarakhand.This a crosssectional study compiling data PWH visiting tertiary care centre Uttarakhand. We collected from patients disorder reporting to July 2017 December 2018. In this...

Introduction: Multicystic dysplastic kidney (McDK) is a rare congenital disorder, resulting from malformation of the during fetal development. It could be unilateral, bilateral or segmental and McDK incompatible with survival. Unilateral occurs in 1 4300 live births combined incidence