Meciusela Tuicakau

ORCID: 0000-0002-3403-3623
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About
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Research Areas
  • Dermatological diseases and infestations
  • Cultural Competency in Health Care
  • Parasitic Diseases Research and Treatment
  • Insects and Parasite Interactions
  • Streptococcal Infections and Treatments
  • Bacterial Identification and Susceptibility Testing
  • Otolaryngology and Infectious Diseases
  • Herpesvirus Infections and Treatments
  • Syphilis Diagnosis and Treatment
  • Garlic and Onion Studies
  • Fungal Infections and Studies
  • Nephrotoxicity and Medicinal Plants
  • Leprosy Research and Treatment
  • Dermatology and Skin Diseases
  • Medicinal Plant Extracts Effects
  • Parasites and Host Interactions
  • Antimicrobial Resistance in Staphylococcus
  • Climate Change and Health Impacts
  • Patient Satisfaction in Healthcare

Ministry Of Health
2013-2024

Fiji National University
2020-2021

Ministry of Health
2015

Southwest University of Visual Arts
2014

Scabies is an underrecognized cause of illness in many developing countries. It associated with impetigo, which can lead to serious systemic complications. We conducted a trial mass drug administration for scabies control Fiji.

10.1056/nejmoa1500987 article EN New England Journal of Medicine 2015-12-10

Scabies and associated impetigo are under-recognized causes of morbidity in many developing countries. To strengthen the evidence base for scabies control we undertook a trial mass treatment scabies. We report on occurrence predictors participants at baseline. Participants were recruited six island communities examined presence impetigo. In addition to descriptive analyses, logistic regression models fit assess association between demographic variables outcome interest. The study enrolled...

10.4269/ajtmh.16-0753 article EN American Journal of Tropical Medicine and Hygiene 2017-07-18

Abstract Background Scabies has been estimated to affect approximately 300 million people worldwide each year. rates are high and pose a significant public health problem in F iji. Community‐based comparison treatment trials have not undertaken. We scabies prevalence compared the efficacy tolerability of mass drug administration ( MDA ) benzyl benzoate lotion BB or oral ivermectin IVM two villages Methods A prospective trial was undertaken ijian villages, comparing three daily applications...

10.1111/ijd.12353 article EN cc-by-nc International Journal of Dermatology 2013-10-29

Scabies is an important predisposing factor of impetigo which can lead to serious bacterial complications. Ivermectin-based mass drug administration substantially reduce scabies and prevalence in endemic settings, but the impact on complications not known.We conducted a before-after trial Northern Division Fiji (population: 131,914) for control. Prospective surveillance was from 2018 2020. Mass took place 2019, involving two doses oral ivermectin or topical permethrin, delivered alongside...

10.1016/j.lanwpc.2022.100433 article EN cc-by-nc-nd The Lancet Regional Health - Western Pacific 2022-03-22

Lymphatic filariasis has remained endemic in Fiji despite repeated mass drug administration using the well-established and safe combination of diethylcarbamazine albendazole (DA) since 2002. In certain settings addition ivermectin to this (IDA) remains a strategy is more efficacious. However, safety yet be described scabies soil-transmitted helminth like Fiji. Villages Rotuma Gau islands were randomised either DA or IDA. Residents received weight-based treatment unblinded with standard...

10.1371/journal.pntd.0008106 article EN cc-by PLoS neglected tropical diseases 2020-03-16

Bancroftian filariasis remains endemic in Fiji despite >10 years of mass drug administration (MDA) using diethylcarbamazine and albendazole (DA). The addition ivermectin to this combination (IDA) has improved efficacy microfilarial clearance at 12 months individually randomized trials nocturnal transmission settings, but impact a setting diurnally subperiodic filarial not been evaluated.This cluster study compared the individual community IDA vs DA as MDA for lymphatic 35 villages on 2...

10.1093/cid/ciab202 article EN Clinical Infectious Diseases 2021-03-15

Kava dermopathy is a common cutaneous effect of regular or heavy use Kava, psychoactive beverage consumed widely throughout the Pacific. In Fiji in 2012, over 1000 study participants underwent full skin examination, and kava was finding. The clinical manifestations share similarities with spectrum autosomal recessive congenital ichthyoses, predominantly lamellar ichthyosis. pathogenesis may be associated functional defect one more cytochrome P450 enzymes implicated epidermal integrity, thus...

10.1111/ijd.12546 article EN International Journal of Dermatology 2014-07-29

Scabies is an important predisposing factor for impetigo but its role in more serious skin and soft tissue infections (SSTIs) not well understood. Information limited on incidence of SSTIs the presence endemic scabies. We conducted a prospective study hospital admissions Northern Division Fiji (population: 131,914). Prospective surveillance with impetigo, abscess, cellulitis, wound infection, pyomyositis, necrotizing fasciitis, infected scabies, crusted scabies was at Division's referral...

10.1371/journal.pntd.0008887 article EN cc-by PLoS neglected tropical diseases 2020-12-09

Background Scabies is a neglected tropical disease hyperendemic to many low- and middle-income countries. can be successfully controlled using mass drug administration (MDA) 2 doses of ivermectin-based treatment. If effective, strategy 1-dose MDA would have substantial advantages for implementing scabies at large scale. Methods findings We did cluster randomised, noninferiority, open-label, 3-group unblinded study comparing the effectiveness control strategies on community prevalence 12...

10.1371/journal.pmed.1003849 article EN cc-by PLoS Medicine 2021-11-10

In 2019, the Murdoch Children’s Research Institute in partnership with Fiji Ministry of Health and Medical Services carried out an integrated mass drug administration (MDA) for treatment scabies lymphatic filariasis Northern Division (population estimate 131,914). We conducted a retrospective micro-costing exercise focused on cost control order to inform budgeting policy decision making endemic setting. collected detailed information financial economic costs incurred by both parties during...

10.1371/journal.pntd.0010147 article EN cc-by PLoS neglected tropical diseases 2022-02-03

Scabies, impetigo, and other skin soft tissue infections (SSTIs) are highly prevalent in many tropical, low-middle income settings, but information regarding their burden of disease is scarce. We conducted surveillance presentations scabies SSTIs, including abscesses, cellulitis, severe SSTI, to primary health facilities Fiji. established a monthly reporting system over the course 50 weeks (July 2018-June 2019) for SSTIs at all 42 public Northern Division Fiji (population, ≈131,914). For...

10.4269/ajtmh.20-1459 article EN American Journal of Tropical Medicine and Hygiene 2021-05-24

BackgroundInvasive Staphylococcus aureus (iSA) and group A Streptococcus (iGAS) impose significant health burdens globally. Both bacteria commonly cause skin soft tissue infections (SSTIs), which can result in invasive disease. Understanding of the incidence iSA iGAS remains limited settings with a high SSTI burden.MethodsProspective surveillance for admissions or was conducted at referral hospital Fiji's Northern Division over 48 weeks between July 2018 June 2019.ResultsThere were 55 15...

10.1016/j.ijid.2021.05.041 article EN cc-by-nc-nd International Journal of Infectious Diseases 2021-05-19

Scabies and related bacterial skin soft tissue infections (SSTIs) are highly prevalent in many tropical, low- middle-income settings. These conditions contribute to higher healthcare costs burdens on systems. The Big Skin Health Intervention Fiji Trial ("Big SHIFT") carried out surveillance for scabies SSTIs from July 2018 June 2019 the Northern Division of Fiji, an area with high prevalence scabies, prior a division-wide ivermectin-based mass drug administration (MDA) campaign. Using data...

10.1371/journal.pgph.0003706 article EN cc-by PLOS Global Public Health 2024-10-10
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