- Streptococcal Infections and Treatments
- Dermatological diseases and infestations
- Parvovirus B19 Infection Studies
- Otolaryngology and Infectious Diseases
- Immunodeficiency and Autoimmune Disorders
- Antimicrobial Resistance in Staphylococcus
- Patient Satisfaction in Healthcare
Murdoch Children's Research Institute
2020-2022
Royal Children's Hospital
2022
Colonial War Memorial Hospital
2017
Abstract The indigenous populations of the South Pacific experience a high burden rheumatic heart disease (RHD). Here we report genome-wide association study (GWAS) RHD susceptibility in 2,852 individuals recruited eight Oceanian countries. Stratifying by ancestry, analysed genotyped and imputed variants Melanesians (607 cases 1,229 controls) before follow-up suggestive loci three further ancestral groups: Polynesians, Asians Mixed or other (totalling 399 617 controls). We identify novel...
Scabies is an important predisposing factor of impetigo which can lead to serious bacterial complications. Ivermectin-based mass drug administration substantially reduce scabies and prevalence in endemic settings, but the impact on complications not known.We conducted a before-after trial Northern Division Fiji (population: 131,914) for control. Prospective surveillance was from 2018 2020. Mass took place 2019, involving two doses oral ivermectin or topical permethrin, delivered alongside...
Scabies is an important predisposing factor for impetigo but its role in more serious skin and soft tissue infections (SSTIs) not well understood. Information limited on incidence of SSTIs the presence endemic scabies. We conducted a prospective study hospital admissions Northern Division Fiji (population: 131,914). Prospective surveillance with impetigo, abscess, cellulitis, wound infection, pyomyositis, necrotizing fasciitis, infected scabies, crusted scabies was at Division's referral...
BackgroundInvasive Staphylococcus aureus (iSA) and group A Streptococcus (iGAS) impose significant health burdens globally. Both bacteria commonly cause skin soft tissue infections (SSTIs), which can result in invasive disease. Understanding of the incidence iSA iGAS remains limited settings with a high SSTI burden.MethodsProspective surveillance for admissions or was conducted at referral hospital Fiji's Northern Division over 48 weeks between July 2018 June 2019.ResultsThere were 55 15...