A5083587589- Streptococcal Infections and Treatments
- Climate Change and Health Impacts
- Systemic Lupus Erythematosus Research
- Global Health Care Issues
- Esophageal and GI Pathology
- Healthcare cost, quality, practices
- Health disparities and outcomes
- Inflammasome and immune disorders
- Aging and Gerontology Research
- Acute Myocardial Infarction Research
- Renal Diseases and Glomerulopathies
- Chronic Kidney Disease and Diabetes
- Acute Kidney Injury Research
- Delphi Technique in Research
- Global Public Health Policies and Epidemiology
- Public Health Policies and Education
- Cardiac Valve Diseases and Treatments
- Surgical Simulation and Training
- Spaceflight effects on biology
- Atherosclerosis and Cardiovascular Diseases
- Immunodeficiency and Autoimmune Disorders
- Agriculture Sustainability and Environmental Impact
- Global Health Workforce Issues
- Air Quality and Health Impacts
- Esophageal Cancer Research and Treatment
Fiji National University
2017-2025
Abstract The indigenous populations of the South Pacific experience a high burden rheumatic heart disease (RHD). Here we report genome-wide association study (GWAS) RHD susceptibility in 2,852 individuals recruited eight Oceanian countries. Stratifying by ancestry, analysed genotyped and imputed variants Melanesians (607 cases 1,229 controls) before follow-up suggestive loci three further ancestral groups: Polynesians, Asians Mixed or other (totalling 399 617 controls). We identify novel...
To characterise the epidemiology and outcomes of Lupus Nephritis (LN) in Fiji. All adult LN cases diagnosed from 2016 to 2020 at national referral hospital were included. Treatment response, kidney failure, dialysis dependence death reported. From 33 cases, a crude annual incidence 2.44 (95% CI 1.73-3.43) per 100,000 population an age-standardised 2.37 0.65-4.09) was derived. The median age 25.7 years (IQR 19.5-32) with predominance indigenous iTaukei ethnicity (67%). Kidney biopsy adequate...
Climate change has been described as the biggest global health threat of 21st century1 and significant implications for gastrointestinal (GI) disease,2 which is focus this consensus commentary provided by World Gastroenterology Organisation (WGO) Change Working Group (CCWG). The CCWG members from 18 countries representing high-income, medium-income low-income populations. WGO includes gastroenterology societies 108 countries, represent more than 60 000 medical practitioner members. members,...
Abstract Rheumatic heart disease (RHD), an autoinflammatory disease, was recently declared a global health priority by the World Health Organization. Here we report genome-wide association study (GWAS) of RHD susceptibility in 1,163 South Asians (672 cases; 491 controls) recruited India and Fiji. We analysed directly obtained imputed genotypes, followed-up associated loci 1,459 Europeans (150 1,309 from UK Biobank study. identify novel signal class III region human leukocyte antigen (HLA)...
Climate change has been described as the greatest public health threat of 21st century. It significant implications for digestive health. A multinational team with representation from all continents, excluding Antarctica and covering 18 countries, formulated a commentary which outlines both ways in this challenge can be faced.
To determine population-based rates of non-fatal complications rheumatic heart disease (RHD). Retrospective cohort study based on multiple sources routine clinical and administrative data amalgamated by probabilistic record-linkage. Fiji, an upper-middle-income country, where most the population has access to government-funded healthcare services. National 2116 patients with clinically apparent RHD aged 5-69 years during 2008 2012. The primary outcome was hospitalisation for any failure,...
Acute Kidney Injury (AKI) is a major and under-recognised cause of morbidity mortality worldwide. Low middle-income countries bear the greatest burden AKI (85%). There currently no published literature on from Pacific Islands. The aim present study was to report incidence, aetiology, management outcomes measures tertiary referral hospital Samoa.Single-centre prospective observational study. Participants were recruited by lead investigator patient information system. inclusion criteria for...
This study aims to evaluate the current state of endoscopy services in Pacific Island Countries (PICs) by quantifying human and material resources, including number trained endoscopists nurses, types procedures performed, availability maintenance endoscopic equipment.
Abstract Background Rheumatic heart disease (RHD) remains an important cause of morbidity and mortality globally. Several reports have linked the to human leukocyte antigen (HLA) locus but with negligible consistency. Methods We undertook a genome-wide association study (GWAS) susceptibility RHD in 1163 South Asians (672 cases; 491 controls) recruited India Fiji. analysed directly obtained imputed genotypes, followed-up associated loci 1459 Europeans (150 1309 from UK Biobank study. For...
Abstract Background Women are disadvantaged by ageing: older women more likely than men to suffer from ill-health, have less access health care and discrimination within the system. Globally, there is a dearth of research on gender ageing with substantial knowledge gaps in low middle-income country contexts. Part wider investigation Fiji, our objective was identify describe gendered differences healthy this Pacific Island context. We believe be first such study region. Methods Applying...
Background: Few population-based estimates of the burden rheumatic heart disease (RHD) are available from low- and middle-income countries. Here we quantify nonfatal complications RHD in Fiji.Methods: Using probabilistic record-linkage, amalgamated multiple sources routine clinical administrative data to define a cohort patients aged 5-69 years covering period 2008-2012. relative survival methods, defined frequency risk factors major within cohort, including failure, atrial fibrillation,...
Abstract Background Women are disadvantaged by ageing: older women more likely than men to suffer from ill-health, have less access health care and discrimination within the system. Globally, there is a dearth of research on gender ageing with substantial knowledge gaps in low middle-income country contexts. Part wider investigation Fiji, our objective was identify describe gendered differences healthy this Pacific Island context which we believe be first such study region. Methods Applying...