Anna Zhu

ORCID: 0000-0002-3432-0593
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About
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Research Areas
  • Urban Green Space and Health
  • Vitamin D Research Studies
  • Land Use and Ecosystem Services
  • Nutritional Studies and Diet
  • Climate Change and Health Impacts
  • Urban Heat Island Mitigation
  • Vitamin C and Antioxidants Research
  • Health disparities and outcomes
  • Air Quality and Health Impacts
  • Noise Effects and Management
  • Molecular Biology Techniques and Applications
  • Inflammatory Biomarkers in Disease Prognosis
  • Diet and metabolism studies
  • BRCA gene mutations in cancer
  • Urban Transport and Accessibility
  • Global Maternal and Child Health
  • Healthcare Systems and Reforms
  • Bone health and osteoporosis research
  • Healthcare cost, quality, practices
  • CRISPR and Genetic Engineering
  • Genomics and Phylogenetic Studies
  • Cardiac, Anesthesia and Surgical Outcomes
  • Genomics and Rare Diseases
  • Genetics, Aging, and Longevity in Model Organisms
  • Geriatric Care and Nursing Homes

German Center for Diabetes Research
2024-2025

Heinrich Heine University Düsseldorf
2024-2025

Deutsches Diabetes-Zentrum e.V.
2024-2025

Tsinghua University
2024

Vanke (China)
2024

German Cancer Research Center
2021-2023

Heidelberg University
2020-2023

University Hospital Heidelberg
2021-2023

Chinese Academy of Medical Sciences & Peking Union Medical College
2023

Duke Kunshan University
2018-2020

BackgroundExposure to natural vegetation, or greenness, might affect health through several pathways, including increased physical activity and social engagement, improved mental health, reductions in exposure air pollution, extreme temperatures, noise. Few studies of the effects greenness have focused on Asia, and, best our knowledge, no study has assessed effect vulnerable oldest-old populations. We association between residential mortality an older cohort China.MethodsWe used five waves...

10.1016/s2542-5196(18)30264-x article EN cc-by The Lancet Planetary Health 2019-01-01

BackgroundBoth air pollution and green space have been shown to affect health. We aimed assess whether greenness protects against pollution-related mortality.MethodsWe used data from the 2008 wave of Chinese Longitudinal Healthy Longevity Survey. calculated contemporaneous normalised difference vegetation index (NDVI) in 500 m radius around each participant's residence. Fine particulate matter (PM2·5) concentration was using 3-year average concentrations 1 km × grid resolution. Cox...

10.1016/s2542-5196(20)30027-9 article EN cc-by-nc-nd The Lancet Planetary Health 2020-03-01

Abstract Vitamin D deficiency is a common health concern worldwide. We aim to compare the prevalence of vitamin among older adults (65+) in China and United States (US). used data from 2011 wave Chinese Longitudinal Healthy Longevity Survey (CLHLS) (n = 2180), 2011–2014 National Health Nutrition Examination (NHANES) US 2283). Serum 25-hydroxyvitamin [25(OH)D] was measured level under 30/50 nmol/L defined as severe deficiency/deficiency. Risk factors were examined by multivariate regression...

10.1038/s41598-019-56297-y article EN cc-by Scientific Reports 2019-12-23

// Dacheng Xie 1 , Jiujie Cui 2 Tian Xia 2,3 Zhiliang Jia Liang Wang Wenfei Wei Anna Zhu Yong Gao 1,2 Keping and Ming Quan Department of Oncology, Shanghai Tongji University Affiliated East Hospital, Shanghai, People's Republic China Gastroenterology, Hepatology Nutrition, The Texas MD Anderson Cancer Center, Houston, TX, USA 3 Changhai Second Military Medical University, Correspondence to: Quan, email: Xie, Keywords : TAZ, EMT, proliferation, metastasis, pancreatic cancer Received August...

10.18632/oncotarget.5772 article EN Oncotarget 2015-09-21

Frailty is an accumulation of deficits characterized by reduced resilience to stressors and increased vulnerability adverse outcomes. There evolving evidence on the health benefits residential greenness, but little known about its impact frailty.

10.1016/j.jamda.2019.11.006 article EN cc-by Journal of the American Medical Directors Association 2019-12-20

The use of colonoscopy has increased and colorectal cancer (CRC) incidence decreased after the introduction screening in Germany. However, it remains unknown to what extent progress been achieved prevention proximal colon, distal rectum.We analyzed trends CRC (2000-2016) mortality (2000-2018) Germany by sex, age, tumor location.The age-standardized declined 22.4% (from 65.3 50.7 per 100 000) men 25.5% 42.7 31.8 women. 35.8% 29.6 19.0 40.5% (19.0 11.3 Despite demographic changes, annual...

10.3238/arztebl.m2021.0111 article EN Deutsches Ärzteblatt international 2021-04-13

Abstract Introduction Plant‐based diets confer health benefits, especially on the prevention of noncommunicable diseases. The relationship between plant‐based dietary patterns cognitive function as a neurological outcome needs more evidence. We aimed to assess associations and among Chinese older adults. Methods used four waves (2008–2018) Longitudinal Healthy Longevity Survey. included 6136 participants aged 65 years with normal cognition at baseline. constructed an overall diet index...

10.1002/brb3.2670 article EN cc-by Brain and Behavior 2022-07-14

Background and Aims Differences of dietary pattern adherence across the novel diabetes endotypes are unknown. This study assessed to pre-specified patterns their associations with cardiovascular risk factors, kidney function, neuropathy among endotypes. Methods Results The cross-sectional analysis included 765 individuals recent-onset (67%) prevalent (33%) from German Diabetes Study (GDS) allocated into severe autoimmune (SAID, 35%), insulin-deficient (SIDD, 3%), insulin-resistant (SIRD,...

10.1016/j.numecd.2023.12.026 article EN cc-by-nc-nd Nutrition Metabolism and Cardiovascular Diseases 2024-01-05

Tissue homeostasis requires somatic stem cell maintenance; however, mechanisms regulating this process during organogenesis are not well understood. Here, we identify asymmetrically renewing basal and luminal cells in the mammary end bud. We demonstrate that SLIT2/ROBO1 signaling regulates choice between self-renewing asymmetric divisions (ACDs) expansive symmetric (SCDs) by governing Inscuteable (mInsc), a key member of spindle orientation machinery, through transcription factor Snail...

10.1016/j.celrep.2015.09.006 article EN cc-by-nc-nd Cell Reports 2015-10-01

Introduction Proximity to vegetated green space has been linked better physical and mental health. However, the relationship between residential greenness cognitive function its decline among older adults is not clear in large cohort studies. Methods Our study used 2000, 2002, 2005, 2008 2011 wave of Chinese Longitudinal Healthy Longevity Survey. We calculated Normalised Difference Vegetation Index (NDVI) using a 500 m radius around participants’ addresses. Mini-Mental State Examination...

10.1136/bmjnph-2019-000030 article EN cc-by BMJ Nutrition Prevention & Health 2019-08-26

Vitamin D metabolism is essential in aging and can be affected by multiple environmental factors. However, most studies conducted single exposure analyses. We aim to assess the individual combined effects of ultraviolet (UV) radiation, residential greenness, fine particulate matter (PM2.5), ozone (O3) on vitamin levels a national cohort study older adults China. used 2012 2014 Chinese Longitudinal Healthy Longevity Survey data, measured same year. interpolated UV radiation from monitoring...

10.1016/j.envint.2022.107523 article EN cc-by-nc-nd Environment International 2022-09-15

Abstract Background Meta‐analyses of randomized controlled trials (RCTs) have demonstrated the efficacy vitamin D supplementation for reduced cancer mortality, all‐cause and respiratory tract infections. However, whether to what extent this translates into effectiveness in real‐world practice is unknown. Methods We assessed association supplement use (as an over‐the‐counter drug or as part a multivitamin product), deficiency (25‐hydroxyvitamin D, 25[OH]D <30 nmol/L), insufficiency...

10.1111/joim.13578 article EN cc-by Journal of Internal Medicine 2022-10-08

Many Asia-Pacific countries are experiencing rapid changes in socio-economic and health system development. This study aims to describe the strategies supporting rural worker attraction retention Cambodia, China, Vietnam explore context influencing their outcomes. paper is a policy analysis based on key informant interviews with stakeholders about province of Vietnam, coupled broad review literature. have implemented medical education, provided financial incentives, personal professional...

10.1186/s12960-018-0340-6 article EN cc-by Human Resources for Health 2019-01-07

Abstract Background Older adults who live alone and have difficulties in activities of daily living (ADLs) may been more vulnerable during the COVID-19 pandemic. However, little is known about pandemic-related changes ADL assistance (such as home care, domiciliary care) its international variation. We examined patterns provision assistance, related these to country-level measures including national income health service expenditure. Methods analysed data covering 29 countries from three...

10.1186/s12877-022-02799-w article EN cc-by BMC Geriatrics 2022-03-04

Abstract Inflammation is a probable biological pathway underlying the relationship between diabetes and depression, but data on differences types symptom clusters of depression are scarce. Therefore, this cross-sectional study aimed to compare associations multimarker panel biomarkers inflammation with depressive symptoms its people type 1 (T1D) 2 (T2D). This combined from five studies including 1260 participants ( n = 706 T1D, 454 T2D). Depressive were assessed using Center for...

10.1038/s41398-024-03209-y article EN cc-by Translational Psychiatry 2025-01-11

We aimed to explore whether higher levels of residential greenness were related lower odds disabilities in activities daily living (ADL) and instrumental (IADL).We included older adults 65 years age or from the Chinese Longitudinal Healthy Longevity Survey. Our exposure was Normalized Difference Vegetation Index 500 m radius around residence. outcome ADL IADL. used binary logistic regression mixed-effects estimate IADL disabilities.A total 36,803 32,316 participants for analysis IADL, with...

10.1097/ee9.0000000000000065 article EN cc-by-nc-nd Environmental Epidemiology 2019-08-30

We tested whether the protective effects of residential greenness on cognitive function differ by APOE ε4 status using Chinese Longitudinal Healthy Longevity Survey (CLHLS). calculated Normalized Difference Vegetation Index (NDVI) 500 m radii around addresses to measure greenness, and Mini-Mental State Examination (MMSE) assess function. dichotomized participants into non-ε4 carriers, carriers. applied generalized estimating equations (GEE) examine association between baseline annual average...

10.1038/s41598-019-57082-7 article EN cc-by Scientific Reports 2020-01-09

Abstract Background China’s TB control system has been transforming its service delivery model from CDC (Centers for Disease Control and Prevention)-led to the designated hospital-led combat high disease burden of TB. The implications new on health workforce development remained unclear. This study aims identify analyze whether well equipped with appropriate workforce. Methods applied mixed methods in Zhejiang, Jilin, Ningxia provinces China. Institutional survey hospitals was conducted...

10.1186/s12960-019-0420-2 article EN cc-by Human Resources for Health 2019-11-12

Vitamin D deficiency is prevalent among older adults. We aimed to study whether residential greenness could alter serum 25(OH)D concentrations as a possible mechanism of greenness's positive health effects.A longitudinal cohort study.We included adults aged ≥65 years from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) with follow-up between 2012 and 2014.We measured by calculating annual average Normalized Difference Vegetation Index (NDVI) in 500 m radius using satellite images...

10.1016/j.jamda.2020.04.026 article EN cc-by Journal of the American Medical Directors Association 2020-06-27
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