- Gastroesophageal reflux and treatments
- Esophageal and GI Pathology
- Eosinophilic Esophagitis
- Dysphagia Assessment and Management
- Helicobacter pylori-related gastroenterology studies
- Pediatric Hepatobiliary Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal motility and disorders
- Pancreatitis Pathology and Treatment
- Esophageal Cancer Research and Treatment
- Liver Disease and Transplantation
- Music Therapy and Health
- Biliary and Gastrointestinal Fistulas
- Amoebic Infections and Treatments
- Eosinophilic Disorders and Syndromes
- Abdominal vascular conditions and treatments
- Organ Transplantation Techniques and Outcomes
- Adolescent and Pediatric Healthcare
- Congenital gastrointestinal and neural anomalies
- Neuroscience and Music Perception
- Metabolism and Genetic Disorders
- Gastrointestinal disorders and treatments
- Pulmonary Hypertension Research and Treatments
- Thyroid Disorders and Treatments
GSL Medical College & General Hospital
2023
Asian Institute of Gastroenterology
2018-2022
Sanjay Gandhi Post Graduate Institute of Medical Sciences
2015-2018
University Gastroenterology
2016
Jawaharlal Institute of Post Graduate Medical Education and Research
2010-2014
Background Disconnected pancreatic duct (DPD) after development of walled-off necrosis (WON) predisposes to recurrent (peri)pancreatic fluid collection (PFC). In this randomized controlled trial, we compared plastic stents with no stent removal a large-caliber metal (LCMS) on incidence PFCs in DPD. Methods Consecutive patients WON who underwent endoscopic ultrasound (EUS)-guided drainage LCMS between September 2017 and March 2020 were screened for eligibility. At (4 weeks drainage), DPD or...
The majority of endoscopic antireflux procedures for GERD are cumbersome to use and randomised long-term data sparse. We conducted such a trial determine the efficacy safety novel, easy full-thickness fundoplication (EFTP) device in patients with GERD.Patients proton pump inhibitor (PPI)-dependent were either EFTP or sham procedure 1:1 ratio. primary endpoint was ≥50% improvement health-related quality life (GERD-HRQL) score at 3 months. Secondary end points included GERD-HRQL, reflux...
Irritable bowel syndrome (IBS) is associated with exaggerated cerebral response including emotional processing following visceral stimulation; though data on this issue available in female IBS patients, it scanty among males. Hence, we aimed to study brain of male patients rectal balloon distension as compared healthy controls using functional magnetic resonance imaging (fMRI). Data between diarrhea and constipation predominant (IBS-D IBS-C) were also compared.Rectal threshold was assessed...
The Indian Motility and Functional Diseases Association the Society of Gastroenterology developed this evidence-based practice guideline for management chronic constipation. A modified Delphi process was used to develop consensus containing 29 statements, which were generated by electronic voting iteration as well face meeting review supporting literature primarily from India. These statements include 9 on epidemiology, clinical presentation, diagnostic criteria; 8 pathophysiology; remaining...
The Indian Neurogastroenterology and Motility Association (INMA), earlier named the Functional Diseases developed this evidence-based practice guidelines for management of irritable bowel syndrome (IBS). A modified Delphi process was used to develop consensus containing 28 statements, which were concerning diagnostic criteria, epidemiology, etiopathogenesis comorbidities, investigations, lifestyle modifications treatments. Owing Coronavirus disease-19 (COVID-19) pandemic, lockdowns mobility...
Background and Aims: Spastic esophageal motility disorders (SEMD) are a rare group of including type III achalasia, distal spasm (DES), Jackhammer esophagus (JHE). Limited data suggest that per-oral endoscopic myotomy (POEM) may be effective in these disorders. In this study, we aimed to evaluate the long-term outcomes POEM SEMD. Methods: The patients with SEMD who underwent (January 2013 December 2019) were analyzed, retrospectively. following recorded: procedure details, technical clinical...
Dapsone can cause several adverse effects, the most serious being dapsone hypersensitivity syndrome (DHS), which is potentially fatal. Here we report a case of severe, life threatening systemic in 17-year-old male who presented with high grade fever, eosinophilia, lymphadenopathy, skin rash, hepatitis and encephalopathy, was managed successfully oral steroids. The reported to emphasize need for timely diagnosis prompt treatment this rare complication successful outcomes. DHS also reviewed brief.
The incidence of gastroesophageal reflux disease (GERD) is high after per-oral endoscopic myotomy (POEM). GERD POEM may be qualitatively different from in patients without motility disorders. In this study, we aimed to analyze and compare aspects between with post-POEM nonachalasia GERD.The data (January 2018 June 2019) were compared that a control group (nonachalasia group), which included presenting typical symptoms associated major Patients lower esophageal sphincter pressure than 10 mmHg...
The use of radioiodine as the first line treatment in Graves' disease is restricted India because its limited availability and an unrealistic risk perception associated with it. Additionally, effectiveness ablation influenced by many factors. Prior medical antithyroid therapy one such important factor.To analyze efficacy low dose (5 mCi) naive patients comparison to that which it was already primed drug, carbimazole.A non-randomized, interventional study conducted Department Medicine...
Though nocturnal acid-breakthrough (NAB) is common in gastroesophageal reflux disease (GERD) patients, its clinical importance results from esophageal acidification, which has been shown to be uncommon. Ilaprazole, a long-acting proton pump inhibitor, may cause NAB infrequently. Accordingly, we studied prospectively, (1) frequency and degree of acidification during NAB, (2) severity while on ilaprazole versus omeprazole.Fifty-eight consecutive patients with GERD once daily ilaprazole, 10 mg...
Karyampudi, Aruna; Srivastava, Priyankab; Mandal, Kausikb; Yadav, Prabhakerc; Ghoshal, Uday C.a; Verma, Abhaia; Phadke, Shubha R.b Author Information
Gastroesophageal reflux disease (GERD) is one of the most commonly encountered gastrointestinal diseases in clinical practice. Proton pump inhibitors (PPI) remain cornerstone treatment GERD. Up to one-third patients do not respond optimal doses PPI and fall into category refractory Moreover, long-term use risk-free, as previously thought. The pathophysiology GERD multifactorial includes related unrelated factors. It therefore paramount address per aetiology for outcomes. management options...
Abstract Background Recently updated guidelines for choledocholithiasis stratify suspected patients into high, intermediate, and low likelihood, with the aim to reduce risk of diagnostic endoscopic retrograde cholangiopancreatography. This approach has increased proportion in intermediate likelihood making it heterogenous. We substratify group so that tests (endoscopic ultrasound/magnetic resonance cholangiopancreatography) are judicially used. Methods is a single-center retrospective...
Hemophagocytic lymphohistiocytosis is a potentially fatal condition characterized by pathologic immune activation, which can complicate infections, childhood systemic rheumatologic diseases and malignancies. Here we report case of reactive hemophagocytic [macrophage activation syndrome] complicating onset juvenile idiopathic arthritis, was treated successfully with dexamethasone cyclosporine. Reactive or macrophage syndrome should be considered in patients arthritis prolonged fever unknown...
A 35-year-old man presented with a 3-year history of intermittent chest pain, dysphagia, and regurgitation (Eckardt score: 5). Gastroscopy barium esophagogram revealed normal-diameter esophagus tertiary contractions in the mid lower no resistance at gastroesophageal junction (GEJ) (Fig. 1). High-resolution manometry (HRM) showed high distal contractile integral 28,013 mm Hg/s/cm >20% swallows, normal integrated relaxation pressure (12.8 Hg) latency (7 seconds), suggestive jackhammer (JHE)...