A5060480759- Phytochemistry and Biological Activities
- Essential Oils and Antimicrobial Activity
- Natural product bioactivities and synthesis
- Phytochemicals and Antioxidant Activities
- Natural Antidiabetic Agents Studies
- Ethnobotanical and Medicinal Plants Studies
- Pharmacological Effects of Natural Compounds
- Drug-Induced Hepatotoxicity and Protection
- Bee Products Chemical Analysis
- Berberine and alkaloids research
- Cholinesterase and Neurodegenerative Diseases
- Curcumin's Biomedical Applications
- Computational Drug Discovery Methods
- Medicinal Plants and Bioactive Compounds
- Alzheimer's disease research and treatments
- Tryptophan and brain disorders
- Antioxidants, Aging, Portulaca oleracea
- Advanced Drug Delivery Systems
- Ziziphus Jujuba Studies and Applications
- Flavonoids in Medical Research
- Catalytic C–H Functionalization Methods
- Alkaloids: synthesis and pharmacology
- Medicinal Plants and Neuroprotection
- Ginger and Zingiberaceae research
- Synthesis and Biological Evaluation
University of Kashmir
2016-2025
University of Mississippi
2014-2015
Jamia Hamdard
2010
Delhi Pharmaceutical Science and Research University
2008
Diabetes is considered as the most common metabolic disease affecting millions of people all around world. Use natural herbal medicines can be effective in treating diabetes. Zingerone (4-(4-hydroxy-3-methylphenyl) butan-2-one) a polyphenolic alkanone extracted from ginger has broad spectrum pharmacological properties and thus used promising candidate against various ailments. In current study we aimed at demonstrating protective effect zingerone diabetes mellitus elucidating its possible...
Colon cancer is a world-wide health problem and one of the most dangerous type cancer, affecting both men women. Naringenin (4, 5, 7-trihydroxyflavanone) major flavone glycoside present in citrus fruits. has long been used Chinese's traditional medicine because its exceptional pharmacological properties non-toxic nature. In study, we investigated chemopreventive potential against 1,2-dimethyhydrazine (DMH)-induced precancerous lesions, that is, aberrant crypt foci (ACF) mucin depleted (MDF),...
Abstract The hypoglycaemic and hypolipidemic potential of ethanol extract C. bursa-pastoris (ECbp) in streptozotocin (STZ)-provoked diabetic rats was evaluated, compounds with their α-amylase α-glucosidase inhibitory were isolated. Acute oral toxicity evaluated rats. Streptozotocin (STZ) (50 mg/kg body weight) injected intraperitoneally into for diabetes induction. In rats, ECbp (0.2 g/kg b.w, p.o.) administered orally 21 days, its outcome on blood glucose levels weight observed a weekly...
Abstract: Depression, which is emerging as one of the most widely prevalent neuropsychiatric disorders worldwide, has affected people across all age groups. However, it currently primarily affecting adults aged 18 to 25. The condition characterized by disrupted sleep cycles, diurnal variation, and disturbed core body temperature rhythms. Currently, anti-depressant medications that are prescribed authorized, such tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors...
Homogenous electrochemical sensing using unmodified electrodes remove electrode fabrication challenges and prove effective for detecting sensitive bio-analytes without chances of surface degradation. This work envisages design optimization a ruthenium(ii) half-sandwich complex as supradecorated homogeneous sensor simultaneous detection rifampicin (RIF) isoniazid (INH) first-line anti-tuberculosis drugs in aqueous environments. The profile GCE/ruthenium(ii) was analyzed cyclic voltammetry,...
The aim of this study was to examine hepatoprotective effect ethanolic extract propolis ( KPEt ) from Kashmir Himalaya against isoniazid and rifampicin (INH-RIF) induced liver damage in rats. Hepatic cellular injury initiated by administration INH-RIF combination (100 mg/kg) intraperitoneal (i.p.) injection for 14 days. We report the protective effects oxidative stress, inflammation, enzymatic nonenzymatic antioxidants. Oral at both doses (200 400 mg/kg body weight) distinctly restricted all...
Inflammation is a cornerstone in numerous pathological conditions, prompting growing hobby exploring natural compounds as capability modulators of inflammatory responses. This complete evaluation synthesizes the current information on tricky interaction between irritation and compounds, elucidating their mechanisms action, sources, categories. Focusing multifaceted roles those overview delineates impact pivotal pathways cellular objectives. Furthermore, it explores therapeutic ability...
Despite broad spectrum utility of Nardostachys jatamansi (D. Don) DC, little is known about the molecular processes that underlie its anti-Alzheimer action. To investigate targets and therapeutic potential N. for Alzheimer's disease (AD), we used Gas Chromatography-Mass Spectrometry (GC-MS), ADMET analysis, network pharmacology, differential gene expression docking, dynamics (MD) simulations. The STITCH database was creation protein-protein interaction while Cytoscape visualization Kyoto...
Abstract: Rheumatoid arthritis (RA) is the most prevalent form of inflammatory arthritis, characterized by chronic inflammation synovial membrane. Current therapeutic options have advanced RA management significantly, yet limitations like adverse effects and treatment resistance underscore need for novel agents. Recent advancements introduced promising candidates, including BTK inhibitors, JAK TLR4 COX-2 LOX which target specific pathways implicated in pathogenesis. This manuscript provides...
The antibacterial activity of the methanolic extract Marrubium vulgare whole plant was tested by disc diffusion method. Zones Inhibition produced in a dose 50, 100, 200, 400 and 600 mg/ml against selected strains measured compared with those standard discs antibiotic ciprofloxacin (10 ig/ml).
Heterocyclic are a class of compounds that intricately entwined into life processes. Almost more than 90% marketed drugs carry heterocycles. Synthetic chemistry, in turn, allocates cornucopia Among the heterocycles, indole, bicyclic structure consisting six-membered benzene ring fused to five-membered pyrrole with numerous pharmacophores generate library various lead molecules. Due its profound pharmacological profile, indole got wider attention around globe explore it fully interest...