A5035450362- Chronic Obstructive Pulmonary Disease (COPD) Research
- Experimental Learning in Engineering
- Software Engineering Research
- Pulmonary Hypertension Research and Treatments
- Receptor Mechanisms and Signaling
- Neuropeptides and Animal Physiology
- Innovative Teaching Methods
- Tuberculosis Research and Epidemiology
- Software Engineering Techniques and Practices
- Physics and Engineering Research Articles
- Software Reliability and Analysis Research
- Respiratory Support and Mechanisms
- Airway Management and Intubation Techniques
- Inhalation and Respiratory Drug Delivery
- Engineering Education and Curriculum Development
- Software Testing and Debugging Techniques
- Engineering and Materials Science Studies
- Engineering Education and Pedagogy
- Educational Assessment and Pedagogy
- Teaching and Learning Programming
- RNA Interference and Gene Delivery
- Monoclonal and Polyclonal Antibodies Research
- Neonatal Respiratory Health Research
- Software System Performance and Reliability
- Information and Cyber Security
Milwaukee School of Engineering
2012-2024
Ohio Northern University
2020
University of Illinois Urbana-Champaign
2020
Northern University
2020
Bridge University
2018
Roche (Switzerland)
2003-2008
Novartis (Switzerland)
1992-2007
University of Toledo
2006-2007
Federal Ministry of Defence
2001
Sanden (Japan)
1996
The new neuropeptide Y (NPY) Y5 receptor antagonist CGP 71683A displayed high affinity for the cloned rat NPY subtype, but > 1, 000-fold lower Y1, Y2, and Y4 subtypes. In LMTK cells transfected with human receptor, was without intrinsic activity antagonized NPY-induced Ca2+ transients. given intraperitoneally (dose range 1-100 mg/kg) to a series of animal models hypothalamic levels. lean satiated rats significantly increase in food intake induced by intracerebroventricular injection NPY....
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSyntheses of macrolide antibiotics. III. Direct ester and lactone synthesis from S-tert-butyl thioate (thiol ester)Satoru Masamune, Susumu Kamata, Walter SchillingCite this: J. Am. Chem. Soc. 1975, 97, 12, 3515–3516Publication Date (Print):June 1, 1975Publication History Published online1 May 2002Published inissue 1 June 1975https://pubs.acs.org/doi/10.1021/ja00845a039https://doi.org/10.1021/ja00845a039research-articleACS PublicationsRequest reuse...
Due to its function in the rate limiting initial step of renin-angiotensin system, renin is a particularly promising target for drugs designed control hypertension, growing risk health worldwide. Despite vast efforts over more than two decades, no orally efficacious inhibitor had reached market. As result structure-based topological design approach, we have identified novel class small-molecule inhibitors with good oral blood-pressure lowering effects primates. Further lead optimization...
The action of renin is the rate-limiting step renin-angiotensin system (RAS), a key regulator blood pressure. Effective inhibitors directly block RAS entirely at source and, thus, may provide vital weapon for hypertension therapy. Our efforts toward identifying novel small-molecule peptidomimetic have resulted in design transition-state isosteres such as 1 bearing an all-carbon 8-phenyl-octanecarboxamide framework. Optimization extended P3 portion and extensive P2' modifications provided...
Abstract Certain frequency distributions which resemble a Poisson distribution, but not quite closely enough, may sometimes be better represented as the sum of two Poissons. A method for dichotomy and subsequent summation is described, twenty-nine to was supposedly good fit, are analyzed.
The field of software engineering is ever changing.The latest IEEE Curriculum Guidelines, SE2014: Guidelines for Undergraduate Degree Programs in Software Engineering was published 2014.Since then, the discipline has continued to evolve as complexity systems reached unprecedented levels.This growth resulted organizations shifting a form development referred DevOps.DevOps "an interdisciplinary approach and means enable realization successful systems" [1] recently been standardized by IEEE.In...
Abstract NOTE: The first page of text has been automatically extracted and included below in lieu an abstract Issues Affecting Doctoral Students Returning to Engineering Education Following Extensive Industrial Experience It can be said that the best time for engineer who desires enter academia earn their Degree is after a four five year period working industry. During this period, practicing engineering extensively exposed practical aspect discipline. This exposure aid more effective...
Journal Article THYROID-OVARIAN RELATIONS II. THE EFFECT OF CASTRATION AND REPLACEMENT THERAPY ON THYROID, PITUITARY, ADRENAL BODY WEIGHT IN THYROHYPER-PLASTIC ALBINO RATS Get access WALTER SCHILLING, SCHILLING 1From the Department of Obstetrics and Gynecology, Stanford University School Medicine SAN FRANCISCO, CALIFORNIA Search for other works by this author on: Oxford Academic Google Scholar GERT L. LAQUEUR Endocrinology, Volume 29, Issue 1, 1 July 1941, Pages 103–107,...
Abstract Behandlung des Thioats (I) mit Hg‐trifluoracetat (II) und Alkoholen, z.B. (III), in Acetonitril liefert die Ester (IV).
Bi-weekly injections of 50 i.u. aqueous theelin over a period 165 to 368 days in male white rats implanted with adenofibroma did not prevent these tumors from undergoing fibromatous changes except one tumor growing 160-day-old theelin-treated animal, which underwent massive glandular hyperplasia. A reduction body weight after large doses theelin, as reported previously, occur either age group smaller amounts given longer periods, nor the amount affect daily growth rate adenofibroma, Strain 1-a.