A5084296500- Renal cell carcinoma treatment
- Bladder and Urothelial Cancer Treatments
- Renal Transplantation Outcomes and Treatments
- Cancer Immunotherapy and Biomarkers
- Urinary Tract Infections Management
- Urologic and reproductive health conditions
- Urinary and Genital Oncology Studies
- Urinary Bladder and Prostate Research
- Economic and Financial Impacts of Cancer
- Organ Transplantation Techniques and Outcomes
- Antibiotics Pharmacokinetics and Efficacy
- Pancreatic and Hepatic Oncology Research
- Neonatal Health and Biochemistry
- Hernia repair and management
- Testicular diseases and treatments
- Sexual Differentiation and Disorders
- Surface Modification and Superhydrophobicity
- Genetic and Kidney Cyst Diseases
- Cancer Cells and Metastasis
- Prostate Cancer Diagnosis and Treatment
- Diamond and Carbon-based Materials Research
- Transplantation: Methods and Outcomes
- DNA Repair Mechanisms
- Bacterial Identification and Susceptibility Testing
- Pediatric Urology and Nephrology Studies
National Hospital Organization
2022-2023
Okayama Medical Center
2022-2023
Okayama University
2019-2021
Okayama University Hospital
2021
To examine anti-adhesion and anti-biofilm effects of a diamond-like carbon coating deposited via novel technique on the inner surface thin silicon tube.Diamond-like coatings were into lumen tube with diameters 2 mm. The was evaluated using physicochemical methods. We used three clinical isolates including green fluorescent protein-expressing Pseudomonas aeruginosa, Escherichia coli Staphylococcus aureus. employed continuous flow system for evaluation both bacterial adhesion biofilm...
Abstract Background The advantages of photodynamic diagnostic technology using 5-aminolevulinic acid (ALA-PDD) have been established. aim this prospective cohort study was to evaluate the usefulness ALA-PDD diagnose upper tract urothelial carcinoma (UT-UC) Olympus VISERA ELITE video system. Methods We carried out a prospective, interventional, non-randomized, non-contrast and open label pilot that involved patients who underwent ureterorenoscopy (URS) detect UT-UC. hydrochloride orally...
A 49-year-old Asian male, who had undergone hemodialysis for >16 years, complained of a fever, dysgeusia and dysosmia, was diagnosed with COVID-19 pneumonia based on severe acute respiratory syndrome coronavirus 2 polymerase chain reaction (SARS-CoV-2 PCR) computed tomography (CT). Treatment started oral favipiravir ciclesonide inhalation. On the 10th day treatment, patient persistent high fever chest CT showed exacerbation pneumonia, so dexamethasone intravenously started. He discharged...
Silicone tubing is used in small-diameter long-sized tubes for medical applications, such as urinary catheters. However, bacteria urine adhere to the catheters, forming colonies and biofilms resulting blockages tract infections. Therefore, we have reported a method of AC high-voltage plasma chemical vapor deposition prevent bacterial adhesion by depositing diamond-like carbon (DLC) on lumen silicone catheter smoothing surface. sp3/sp2 structure DLC surface unresolved, biomimetic with...
Abstract Objectives To compare the donor outcomes of living kidney transplantation between standard donors (SDs) and marginal (MDs) including diabetic patients (MD + DM). Methods MDs were defined according to Japanese guideline criteria: (a) age >70‐years, (b) blood pressure ≤130/80 mmHg on hypertension medicine, (c) body mass index >25 ≤32 kg/m 2 , (d) 24‐h creatinine clearance ≥70 <80 ml/min/1.73 m (e) hemoglobin A1c > 6.2 or ≤6.5 with oral medicine. Fifty‐three 114 MDs. We...
Abstract Purpose This study aimed to investigate the effectiveness of Geriatric Nutritional Risk Index (GNRI) in predicting efficacy first-line immune checkpoint inhibitor (ICI) combination therapy for metastatic or unresectable renal cell carcinoma (RCC) and associated patient prognosis. Methods A retrospective was conducted using data from 19 institutions. The GNRI calculated body mass index serum albumin level, patients were classified into two groups values, with 98 set as cutoff point....
Background/Aim: This study aimed to elucidate the detailed characteristics of CYP3A5 expression and association between clinical outcomes in patients with renal cell carcinoma (RCC). Patients Methods: retrospectively enrolled 124 Japanese RCC treated at Okayama University Hospital. The commonest gene polymorphism, CYP3A5*3, levels mRNA protein each tissue were examined. Results: Expression tissues was significantly down-regulated compared that adjacent normal tissues. High level extended...
We report a 62-year-old male with metastatic fumarate hydratase-deficient renal cell carcinoma (FH-deficient RCC) without hydratase (FH) mutation (FH-deficient-like RCC). The International Metastatic RCC Database Consortium risk score was intermediate, and immunotherapy nivolumab ipilimumab (Ipi/ Nivo) initiated. Four cycles of Ipi/Nivo 5 resulted in complete response the metastases. Hypophysitis occurred as an immune-related adverse event after four Ipi/Nivo. prognosis patients FH-deficient...
Extramammary myofibroblastomas are extremely rare.The patient was an 88-year-old male. He presented for evaluation of frequent urination and a "pushing up" sensation from the groin during defecation. Thorough physical radiographic examinations revealed retroperitoneal tumor on right side rectum. The pathologic examination biopsy tissue showed that unlikely to be malignant. Nevertheless, symptomatic thus underwent laparoscopic resection through transperitoneal approach. circumscribed with...
The aim of this ongoing trial is to evaluate the clinical efficacy and safety sitafloxacin (STFX) 200 mg once daily (QD) for 7 days in patients with refractory genitourinary tract infections, which include recurrent or complicated cystitis, pyelonephritis, bacterial prostatitis, epididymitis. primary endpoint microbiological at 5-9 after last administration STFX. Recruitment began February 2021, target total sample size 92 participants.
Birt-Hogg-Dubé (BHD) syndrome is an autosomal dominant disorder caused by germline mutations in the folliculin gene (FLCN). It characterized skin tumors, multiple lung cysts, and renal tumors. Active genetic testing appropriate periodic examinations of family lines patients with BHD have not been widely performed. In this report, we present our experience regarding diagnosis asymptomatic members syndrome. The proband was a 65-year-old female history colorectal cancer spontaneous pneumothorax...
The usefulness of the urine loss ratio in early postoperative period for prognosis long-term urinary continence after radical prostatectomy has not been fully determined.All patients who underwent prostate cancer at our institution between November 2015 and March 2021 were retrospectively included. We investigated rate achievement 1 year surgery, as well associated risk factors reduced achievement, classified by every 10% ratio.Of 100 with available data, 66 achieved continence. Ninety-three...
We report a 47-year-old Japanese female with 10 previous treatments for multiple bilateral renal cell carcinoma (RCC) associated von Hippel-Lindau disease. The 14-mm right lower pole tumor was in contact the ureter. Laparoscopic cryoablation performed to protect ureter wrapped gauze. Computed tomography (CT) monitoring used confirm precise ≥ 6 mm ice-ball margin. There no local progression at 6-months post-surgery. serum creatinine has been stable. This is apparently first of combined...
Abstract Background: The advantages of photodynamic diagnostic technology using 5-aminolevulinic (ALA-PDD) have been established. aim this prospective cohort study was to evaluate the usefulness ALA-PDD diagnose upper tract urothelial carcinoma (UT-UC) Olympus VISERA ELITE ® video system. Methods: We carried out a prospective, interventional, non-randomized, non-contrast and open label pilot that involved patients who underwent ureterorenoscopy (URS) detect UT-UC. 5-ALA HCl orally...