- Tracheal and airway disorders
- Lung Cancer Diagnosis and Treatment
- Myasthenia Gravis and Thymoma
- Sarcoma Diagnosis and Treatment
- Cardiac tumors and thrombi
- Medical Imaging and Pathology Studies
- Liver Disease Diagnosis and Treatment
- Speech and Audio Processing
- Dialysis and Renal Disease Management
- Congenital Diaphragmatic Hernia Studies
- Renal cell carcinoma treatment
- Pituitary Gland Disorders and Treatments
- Pharmacogenetics and Drug Metabolism
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Advanced Data Compression Techniques
- Meningioma and schwannoma management
- Complementary and Alternative Medicine Studies
- Oral and Maxillofacial Pathology
- Pancreatitis Pathology and Treatment
- Soft tissue tumor case studies
- Acupuncture Treatment Research Studies
- Liver physiology and pathology
- Vector-Borne Animal Diseases
- Hepatitis C virus research
Pharmaceuticals and Medical Devices Agency
2025
Okayama University
2018-2024
NTT Medical Center
2016-2023
Kasugai Municipal Hospital
2021-2023
Gifu University
2005-2023
Pharmac
2023
King Edward Memorial Hospital
2023
St John of God Subiaco Hospital
2023
Okayama University Hospital
2022
Tosei General Hospital
2021
Bone morphogenetic protein (BMP) was extracted from human dentin matrix with 4 mol/L guanidine-HCl and purified by liquid chromatography. SDS-PAGE IEF showed that the BMP homogeneous induced new bone formation in situ after three weeks when implanted into muscle pouches Wistar rats. The molecular weight of estimated to be about 20.0 kDa SDS-PAGE, pI value 8.8 IEF. Amino acid analysis suggested is a containing 191 amino acids. A partial sequence obtained final BMP. Dentin-matrix-derived...
Linezolid (LZD) is an antimicrobial that commonly used for treatment of vancomycin-resistant Enterococci and methicillin-resistant Staphylococcus aureus infections. However, the development thrombocytopenia, one most frequent adverse side effects this antimicrobial, can lead to discontinuation LZD treatment. While clinical studies indicate risk factors LZD-induced thrombocytopenia include >14 consecutive days, renal dysfunction, chronic liver disease, fundamental mechanism governing...
HTLV-1 infection causes adult T-cell leukemia (ATL). The development of ATL is thought to be associated with disruption transcriptional control cellular genes. basic leucine-zipper (bZIP) factor, HBZ, encoded by the complementary strand provirus. We previously reported that HBZ interacts c-Jun and suppresses its activity. To identify factor(s) interact we conducted a yeast two-hybrid screen using full-length as bait identified MafB. heterodimerizes MafB via each bZIP domain. Luciferase...
<b><i>Background:</i></b> The neuraminidase inhibitors (NAIs) oseltamivir, zanamivir, laninamivir and peramivir are available in Japan. However, the selective use of NAIs for treating outpatients with influenza has not been clearly defined. <b><i>Methods:</i></b> We assigned 191 patients to 4 groups, each treated a different NAI, then compared how long it took alleviate fever other symptoms eliminate virus....
Background: It is unclear whether use of a proton pump inhibitors (PPIs) increases the risk rhabdomyolysis. Objective: To clarify PPIs Methods: This cross-sectional study analyzed data entered into Medical Data Vision (MDV) database in Japan and U.S. Food Drug Administration Adverse Event Reporting System (FAERS). The MDV were to evaluate association between Then, FAERS rhabdomyolysis was increased further when statin or fibrate used concomitantly with PPI. In both analyses, histamine-2...
Vanadium is widely distributed in the environment and exhibits various biological physiological effects human body. We previously documented neuroprotective effect of sodium orthovanadate (SOV) against rodents i.v. injected with 2 ml/kg 50 mM SOV just after induction middle cerebral artery occlusion (MCAO; 0 min post-MCAO). To evaluate its potential clinical use, we determined here therapeutic time window (0, 45, 90 post-MCAO) dose (2 ml/kg, 12.5, 25, 37.5, mM) rats. A single injection at or...
A speech coding algorithm for application to the Japan digital cellular half-rate coder has been developed based on multiband excitation (MBE) using 3.0 kbit/s. The target performance is at same level as that of a full-rate operating 6.7 quantization scheme spectral envelope MBE parameters described. New features include an efficient dimension converter, interframe vectors, and multistage vector with interpolative quantization. simplified model voiced/unvoiced division method...
Solitary pulmonary capillary hemangioma (SPCH) is a rare disease, first described about autopsy cases in 2000 and surgically resected 2006. To date, only 9 have been published English. Here, we report 7 original with surgery (median age, 54 y; 4 females, 2 never-smokers). All patients were asymptomatic, all nodules detected by computed tomography (CT). The median (range) size of nodule was 11 (8 to 16) mm. Six showed the part-solid appearance 1 pure ground-glass CT findings. growth speed...
Abstract Virtual-assisted lung mapping is a bronchoscopic multiple dye marking technique that facilitates sublobar resections for unidentifiable pulmonary tumors. Marking failure reportedly occurs in 10% of cases. To overcome this limitation, we developed indocyanine green virtual-assisted uses addition to indigo carmine. Here, report our initial experience mapping.
An efficient coding scheme for linear predictive (LPC) residuals is proposed based on harmonic and noise representation. New features of the include classified vector quantization spectral envelope LPC with a weighted distortion measure. The improvement in performance obtained by classifying codebooks voiced/unvoiced (V/UV) decision shown. Sequences short-term RMS power time domain waveforms are also quantized transmitted unvoiced signals. A fast synthesis algorithm voiced signals using an...