A5100386320- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Catalytic C–H Functionalization Methods
- MicroRNA in disease regulation
- Yeasts and Rust Fungi Studies
- Cancer-related gene regulation
- Cell death mechanisms and regulation
- Cyclopropane Reaction Mechanisms
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Skin and Cellular Biology Research
- Sulfur-Based Synthesis Techniques
- Cancer Mechanisms and Therapy
- Protein Degradation and Inhibitors
- Synthesis and characterization of novel inorganic/organometallic compounds
- Cancer-related Molecular Pathways
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cellular transport and secretion
- Glycosylation and Glycoproteins Research
- Catalytic Alkyne Reactions
- Supramolecular Chemistry and Complexes
- Berry genetics and cultivation research
- Insect Pest Control Strategies
- American Literature and Humor Studies
- American and British Literature Analysis
- Coordination Chemistry and Organometallics
Shangqiu Normal University
2017-2024
Gansu Agricultural University
2021-2022
Tongji University
2022
Northeast Forestry University
2021
Henan University
2017
Kaifeng University
2017
Hunan Agricultural University
2011
Shangqiu Institute of Technology
2009
Umeå University
2000
Abstract BACKGROUND Gypsy moth ( Lymantria dispar ) is one of the most important pests in world. Emamectin benzoate (EMB) widely used control agricultural and forestry pests. Here, we explored sublethal effects EMB on gypsy moths order to better understand toxicological mechanism EMB. RESULTS The concentration exposure significantly decreased larvae body weight. To further explore mechanism, indicators related digestion nutrient metabolism were detected. results showed that caused midgut...
Circular RNAs (circRNAs) play important roles in the progression of human cancers. circRNA nuclear receptor interacting protein 1 (circNRIP1) has been reported to as an oncogene gastric cancer. However, mechanism underlying circNRIP1 cancer is far from understood.Forty-five patients were recruited and overall survival was analyzed. Gastric cell lines MGC-803 AGS cells cultured for study vitro. The expression levels circNRIP1, microRNA (miR)-182 rho-associated kinase (ROCK1) detected by...
Circular RNAs (circRNAs) are a kind of non-coding RNA that have an important molecular function in mammary gland development and lactation mammals. In our previous study, circ_015343 was found to be highly expressed the ovine tissue at peak-lactation period by using sequencing (RNA-seq). present authenticity confirmed reverse transcriptase-polymerase chain reaction (RT-PCR) analysis Sanger sequencing. The derived from complete 10 exons aminoadipic semialdehyde synthase (AASS), ranging exon 2...
Herein, we report an intramolecular 6-endo-dig cyclization of N-ferrocenyl propiolamides for the synthesis planar chiral ferrocenes enabled by gold(I)-catalyzed hydroarylation. By using this protocol, a variety ferrocenopyridin-2(1H)-ones were obtained in good yields and excellent enantioselectivities (up to 96% ee).
The all-thiophene-based double helix DH-1 was designed and prepared originally from the selective deprotonation of cyclooctatetrathiophene (tetra[3,4]thienylene, COTh) following Negishi coupling reaction with 3,3′-bithiophene. X-ray crystallographic studies revealed that has a double-helical scaffold. arylations including tetraphenylation tetrathienylation were efficiently employed to replace four α-protons central COTh phenyl thiophenyl groups via cross-coupling reactions. chiral resolution...
The sequential lithiation mechanism for the selective deprotonation of tetra[3,4]thienylene (<bold>1</bold>) to form <bold>Li4-1</bold> in present <italic>n</italic>-BuLi THF is investigated.
Circular RNA (circRNA/circ) profiles have been suggested to be involved in the prognosis of several types solid tumors and hematological malignancies, including multiple myeloma (MM). Therefore, aim present study was comprehensively explore involvement circRNA MM prognosis. A total 60 patients with that underwent bortezomib‑based induction therapy were enrolled. Next, eight complete response (CR) no (NR) randomly selected detect their bone marrow plasma cells (BMPCs) by microarray. 10...
4-Aryl-3,4-dihydrocoumarins are one of the most important structural motifs.
A novel approach for the α-alkylation of ketones was developed using Brønsted acid-catalyzed C-C bond cleavage. Both aromatic and aliphatic reacted smoothly with 2-substituted 1,3-diphenylpropane-1,3-diones to afford products high yields excellent regioselectivity, in which 1,3-dicarbonyl group acted as a leaving presence catalyst TfOH. Mechanism experiments showed that β-C-C cleavage diketone shift equilibrium towards enol formation from ketone are driving forces induce desired products.
<div>Abstract<p>Early growth response gene (EGR1) is a transcription factor known to be downstream effector of B-cell receptor signaling and Janus kinase 1 (JAK1) in diffuse large lymphoma (DLBCL). While EGR1 characterized as tumor suppressor leukemia multiple myeloma, the role unknown. Here we demonstrate that potential oncogene promotes cell proliferation DLBCL. IHC analysis revealed expression elevated DLBCL compared with normal lymphoid tissues level higher activated B...
Abstract Background: Circular RNAs (circRNAs) are a class of non-coding RNA that play crucial roles in the development skeletal muscle. However, little is known about role circRNAs caprine In this study, muscle fiber size and expression profiles were compared Longissimus dorsi Liaoning cashmere (LC) goats Ziwuling black (ZB) with significant phenotypic differences meat production performance, using hematoxylin eosin staining RNA-Seq, respectively. Results: The LC larger than those ZB ( P...