- Skin Diseases and Diabetes
- Genetic and rare skin diseases.
- Cancer-related molecular mechanisms research
- Liver Disease and Transplantation
- MicroRNA in disease regulation
- Autoimmune Bullous Skin Diseases
- RNA Research and Splicing
- Nail Diseases and Treatments
- Renal Diseases and Glomerulopathies
- Liver Disease Diagnosis and Treatment
- Renal Transplantation Outcomes and Treatments
- Dermatological and Skeletal Disorders
- Sympathectomy and Hyperhidrosis Treatments
- Cervical Cancer and HPV Research
- T-cell and B-cell Immunology
- Enterobacteriaceae and Cronobacter Research
- Acne and Rosacea Treatments and Effects
- Circular RNAs in diseases
- Tourism, Volunteerism, and Development
- Turkish Literature and Culture
- Youth Development and Social Support
- Education Practices and Challenges
- Bacillus and Francisella bacterial research
- Chemotherapy-related skin toxicity
- Cell death mechanisms and regulation
Sağlık Bilimleri Üniversitesi
2025
Ankara Onkoloji Eğitim ve Araştırma Hastanesi
2025
Western University
2024
Başkent University
2018-2021
Ankara University
2021
University Health Care System
2018
Inonu University
2016-2017
Trakya University
2017
Süleyman Demirel University
2017
Malatya Devlet Hastanesi
2016
Introduction: Most of Bacillus spp. generally avirulent species in healthy patients, but if there is a fragile the patient, especially their immune system, can be an agent for infections. Case Report: In this case, we report that paranthracis, diagnosed by whole genome sequencing, responsible bacteremia T-ALL patient. A 26-year-old male patient was with T-cell acute lymphoblastic leukemia. paranthracis isolated from two sets blood cultures obtained febrile neutropenia. Results: The bacteria...
Amaç:
Paraspeckles are nuclear condensates formed by NEAT1_2 lncRNA and different RNA-binding proteins. In general, these membraneless organelles function in the regulation of gene expression translation miRNA processing, doing this, they regulate cellular homeostasis mediate pro-survival cell. Despite evidence showing importance paraspeckles stress response, dynamics their components under conditions osmotic remain unknown. We exposed HEK293T cells to sorbitol examined using real-time PCR....
Atypical glandular cells (AGCs) in Pap (Papanicolaou) smears are uncommon but may represent various benign and malignant lesions. The aim of this study was to evaluate the AGC incidence smears, analyse relationship between malignancy, reveal importance architectural nuclear features observed cytologically malignancies.Patients diagnosed with on basis cervicovaginal cytology May 2011 July 2018 were included study. All slides retrospectively reviewed subclassified according Bethesda 2001...
Breast cancer is the most common in women. The human epidermal growth factor receptor 2 (HER2) overexpressing subtype related to poor prognosis with an aggressive phenotype and reported as one of commonly seen subtypes. Trastuzumab prevalently used a treatment method for HER2+ breast however, resistance drug frequently occurs following treatment. MicroRNAs (miRNAs) are 19-23 nucleotide long small RNAs, which regulate gene expression at posttranscriptional level studies show that there...
Lichen myxedematosus is a chronic, inflammatory, systemic dermatose characterized by dermal musin deposition and increased fibroblasts in the absence of thyroid dysfunction.It usually seen together with paraproteinemia.It clinically classified as scleromyxedema (papular mucinosis), localized lichen myxedematosus, atypical myxedematosus.Etiopathogenesis disease which very difficult to treat still unknown.Herein, we present case without monoclonal gammopathy mimicking angioedema, rapidly...
Acne vulgaris (AV) is a common pilosebase unit disease characterized by peripheral inflammation. Because it associated with the nervous system, cranial system and autonomic skin neuroimmunoendocrine organ. Various neuroendocrine hormones catecholamines are also released keratinocytes, which stimulate inflammation in unit. In this study, sympathetic response (SSR) evaluating function as reflex against internal external stimuli AV will be evaluated. 31 patients (mean age: 22.48 ± 2.35, 20...
Türkderm-Deri Hastalıkları ve Frengi Arşivi Dergisi, Galenos Yayınevi tarafından basılmıştır
Abstract Background: Understanding the existence of a cycle, where psychological disturbances cause skin diseases and in turn, disorders, provides basis for good dermatological practice. Objective: The aim this case-control study is to examine psychiatric morbidity disorders children adolescents with no history disorders. Method: In study, 502 participants (251 patients 251 healthy individuals) were evaluated according DSM-IV criteria. All interviewed using Turkish version Kiddie Schedule...
Background: Hypercholesterolemia (HC) impairs angiogenesis and induces apoptosis in livers. This hyperlipidemic impairment of reported to associated with reduced bFGF. HGF stimulates proliferation, angiogenesis, plays a critical role the regeneration process liver. also acted as metabolic regulator increases patients hyperlipidemia. We evaluate whether has protective effect on hepatocytes recipients HC. Methods: Biopsies 68 scored for steatosis, fibrosis, inflammation. Angiogenesis...
Introduction: Although partial liver allografts from living donors have near-complete regeneration of their volumes within weeks after transplantation, the microscopic range is not well known. HGF plays critical roles in process various tissues by stimulating proliferation, vascularisation, and migration progenitor cells. exerts protective effects on organs via anti-apoptotic anti-inflammatory signals. Our aim two folds; first, to evaluate regenerative effect allografts, second, analyze...
Granuloma annulare is relatively common idiopathic disease of dermis and subcutaneous tissue.It can be observed all races ages, but it effects woman more often (2:1).Widespread granuloma annulare, diffuse symmetrically located occurs as papular or annular pustules composed than ten hundreds lesions.Because the rare occurrence cases with photosensitivity distribution, we present a case 49 year-old who had generalized on neck, dorsal aspects hands extensor surfaces arms showing photosensitive...
Introduction Interaction of PD-1 with PD-L1 has been shown to decrease T-cell proliferation and survival T cells is thought exert inhibitory functions in experimental models autoimmune diseases transplantation. Despite the critical role biology increasing knowledge function solid organ transplantation, its AMR unknown. Although some studies demonstrated that PD-1/PD-L1 interaction essential for maintenance graft tolerance, renal allografts might different effects on immune cells. Since...
Background: Rapamycin (Rp) is known to decrease VEGF synthesis, making it an option for recipients who develop malignant diseases. Anti-angiogenic and anti-proliferative properties of Rp also promote their usage in transplant delay the development allograft vasculopathy. Whereas use may be complicated by proteinuria glomerulosclerosis (GS) renal allografts. Because plays a crucial role glomerular function vascular remodeling, we aimed understand effect on expression and, therefore prognosis....
Background: EMT of tubular cells and EndoMT PTCs are the crucial processes in pathogenesis interstitial fibrosis (IF) chronic allograft nephropathy. Rapamycin (Rp) has shown to reduce profibrotic gene expression both experimental clinical settings. The effects commonly used immunosuppressive on development renal allografts not well known. We aimed show influence Rp, cyclosporin A (CsA) tacrolimus (Tac) Endo MT allografts. Methods: Of 150 patients, 53 was under therapy (Group R), 49 T) 48 CsA...