Abstract The objective of this study was to analyze the clinical benefit histopathologic analysis appendectomy specimens from patients with an initial diagnosis acute appendicitis. We retrospectively analyzed demographic and data 1255 (712 males, 543 females; age range, 17–85 years) who underwent treat Patients incidental during other surgeries were excluded study. Histopathologic findings used confirm diagnosis. Ninety-four percent positive for Of those, 880 phlegmonous appendicitis, 148...

Squamous cell carcinoma (SCC) of the renal pelvis is a rare neoplasm and usually associated with long standing stone disease. This tumor aggressive in nature has poor prognosis. We report case who presented sudden significant weight loss. During radiologic investigation, mass staghorn calculi were detected right kidney. The patient subsequently underwent radical nephrectomy. Pathological diagnosis was SCC extensive infiltration to parenchyma. imaging features histopathologic findings this...

CT plays a valuable role in assessment of patients with wide variety diseases the pleura, and pulmonologists should be aware significance different findings for differential diagnosis benign malignant pleural diseases.155 disease who had undergone scans lungs thorax before treatment were enrolled. We retrospectively reviewed 146 proven disease.Fifty-nine cases malignant, 87 them diseases. that helpful distinguishing from were: 1) nodularity; 2) rind; 3) mediastinal involvement; 4) thickening...

ABSTRACT Background: The most important prognostic parameter is staging in colorectal cancers, and tumor budding (TB) among the independent parameters that are increasing significance. Cyclin D1 expression has been associated with poor prognosis as a marker of various tumors. Aims Objectives: In this study, aim was to determine activity cyclin colon adenocarcinomas, tumors, buds compare results parameters. Materials Methods: This study included 167 patients who were operated on for subjects,...

Objectives Endometrial cancer is the most frequent tumor of female genital tract. Ubiquitin a small protein (8.5 kDa) found in all eukaryotic cells, binds to substrate proteins via three-phase enzymatic pathway referred as ubiquitination and plays an important role cellular stability. Neural precursor cell-expressed developmentally down-regulated 4-like (NEDD4L) functions last phase this process. In study, we investigated NEDD4L expression endometrial cancer. Methods The study participants...

Objective: We aimed to determine the frequency of endometrial pathologies patients who presented our outpatient clinic with postmenopausal bleeding (PMB) and asymptomatic menopausal a finding thickened endometrium on transvaginal ultrasonography.Study Design: This study was performed at Bezmialem University Hospital. Women from January 2015 2017 were analyzed. Patients divided two groups. All underwent ultrasound 7.5 MHz probe. Endometrial sampling by either blind D&C (dilatation &...

Abstract Background Use of smokeless tobacco (ST) is increasing in many communities. We investigated whether ST alters the cytological and cytomorphometric features buccal mucosa cells. Methods Twenty male participants who had used Nicotiana rustica Linn.‐containing (Maras powder) for at least 10 years, 20 healthy controls did not use ST, were included this study. After rinsing mouth with water, samples taken using a toothbrush from subjects both groups. Samples gently spread over glass...

Fascioliasis is a rarely encountered parasitic infection in Turkey that mainly affects the liver and bile ducts. Other defined localizations of parasite are lungs, gastrointestinal system, subcutaneous fatty tissue. Two cases female patients who presented to hospital with abdominal pain whose physical examination laboratory findings were normal except peripheral eosinophilia, detected have masses necrotic areas. Segmental hepatectomies performed both preliminary diagnosis tumors. Upon...

Background and Design: Actinic (solar) keratosis (AK) is a precancerous, epidermal lesion, which develops in sensitive skin exposed to sun for long period.AKs are divided into different histopathological subtypes.There link between the clinical progression of subtypes, degree cellular atypia, precancerous nature lesion.Different series have reported that rate transformation AK squamous cell carcinoma (SCC) ranges 12% 20%.Materials Methods: In this study, we reevaluated patients who were...

Clear cell adenofibromas of borderline malignancy are extremely rare tumors ovary. We report a case ovarian clear adenofibroma in 53-year-old postmenopausal woman. The patient had abdominal hysterectomy and bilateral salpingo-oophorectomy because left adnexeal mass. tumor was well-demarcated, solid multinodular mass, measuring 12×10.5×6 cm. Microscopically, the consisted mainly fibrous stroma glands composed cells with eosinophilic or cytoplasm. epithelium focally showed moderate nuclear...

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign vascular tumor. Although its etiology not clearly known, infection, hormonal factors, and trauma are the suspected reasons. There few cases considered to be related pregnancy described in literature. Granulomas rarely seen histopathology only four patients granulomas have been described. Herein, we will present 28-year-old woman who has pregnant three times; every pregnancy, she developed pink nodular lesions on back of her...

Lichen myxedematosus is a chronic, inflammatory, systemic dermatose characterized by dermal musin deposition and increased fibroblasts in the absence of thyroid dysfunction.It usually seen together with paraproteinemia.It clinically classified as scleromyxedema (papular mucinosis), localized lichen myxedematosus, atypical myxedematosus.Etiopathogenesis disease which very difficult to treat still unknown.Herein, we present case without monoclonal gammopathy mimicking angioedema, rapidly...

Immunohistochemical and molecular studies to differentiate eosinophilic kidney tumors are gradually increasing. The present study investigated the role of transient receptor potential cation channel subfamily M member 4 (TRPM4), a non‑selective associated with migration, proliferation invasion in cancer cells, this differentiation. aim was investigate effectiveness TRPM4 differentiation tumors. included total 112 patients, including 97 diagnoses 33 clear cell renal carcinoma (CCRCC), 35...

Objective: Thyroid cancers are the most common malignancy of endocrine organs.It accounts for 1% all cancer.Environmental, genetic and hormonal factors play an important role in its etiology.The aim this study is to investigate incidence thyroid cancer types at thyroidectomy materials city Malatya. Methods:The pathology reports surgical materials, which were sent Inonu University Medical Faculty Pathology Department retrospectively from archives between years January 2007 May...

Intraoperative consultation (IC) is often used for surgical planning in gynecological oncology, primarily ovarian and endometrial cancer surgery.However, there limited research that compares IC diagnoses results from definitive analyses.This retrospective study analysis findings terms of mass carcinoma patients consulted myometrial invasion (MI) depth across 7 years (2012)(2013)(2014)(2015)(2016)(2017)(2018)(2019).IC was performed 282 cases to evaluate masses.The sensitivity 94% benign...

A BSTRACT Background: In the updated World Health Organization Classification of Central Nervous System Tumors, presence CDKN2A/2B homozygous deletion is now recognized as indicative Grade 4 in isocitrate dehydrogenase (IDH) mutant astrocytomas, and it associated with a poor prognosis astrocytomas. Conversely, Beclin 1, crucial protein autophagy initiation, exhibits bidirectional effect on tumor progression suppression. The objective this study to evaluate CDKN2A IDH astrocytomas varying...

The incidence and prevalence of neuroendocrine neoplasms (NENs) in many organs are increasing. Although such NENs have similar grades, they may exhibit quite different behaviors. In this multicenter study, we aimed to investigate the distribution morphological NEN variants non-pancreatic gastrointestinal (GI) tract determine whether can guide prognosis prediction. Two hundred fifty-six patients diagnosed with originating from GI 7 centers were included study. 89 (36.6%) cases, detected. When...

Endolymphatic Sac Tumor is a local aggressive tumor that grows slowly, associated with Von-Hippel-Lindau disease and originated from endolymphatic canal. A 64-year-old male patient VHL admitted to the neurosurgery department of our hospital presented pain behind ear loss sensation on cheek. Cranial magnetic resonance imaging revealed an located in middle left acoustic canal extending pontocerebellar angle eroded mastoid temporal bones. Histopathological examination lesion simple cuboidal...

We aimed to evaluate the characteristics of patients with incidental kidney tumors detected in pathological examination performed after simple nephrectomy due a non-functioning kidney. The pathology results specimens from who underwent diagnosis between January 2012 and March 2021 were retrospectively analyzed. Data regarding demographic information, imaging methods, clinical histopathological features collected. number renal was determined. A total 163 nonfunctioning kidneys included study....

CD47 is a membrane protein that belongs to the immunoglobulin superfamily and regulates macrophage phagocytosis negatively. As expression at cancer cell would inhibit phagocytic activity of immune cells, it connected an unfavorable prognosis in leukemia malignancies various solid organs. Materials and.In this study, retrospectively evaluated 72 patients who had been diagnosed with endometrial carcinoma Pathology Department undergone total abdominal hysterectomy bilateral...