A5029217633- Hepatocellular Carcinoma Treatment and Prognosis
- Intraperitoneal and Appendiceal Malignancies
- Chemotherapy-induced organ toxicity mitigation
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Appendicitis Diagnosis and Management
- Diverticular Disease and Complications
- Liver Disease Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Myasthenia Gravis and Thymoma
- Neurofibromatosis and Schwannoma Cases
- Drug-Induced Hepatotoxicity and Protection
- Neuroendocrine Tumor Research Advances
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Bone Tumor Diagnosis and Treatments
- Pituitary Gland Disorders and Treatments
- Injury Epidemiology and Prevention
- Adrenal and Paraganglionic Tumors
- Congenital Diaphragmatic Hernia Studies
- Sarcoma Diagnosis and Treatment
- Meningioma and schwannoma management
- Metabolism and Genetic Disorders
- Kidney Stones and Urolithiasis Treatments
- Cannabis and Cannabinoid Research
- Burn Injury Management and Outcomes
- Restraint-Related Deaths
Inonu University
2014-2024
Gazi Hastanesi
2024
Malatya Devlet Hastanesi
2011-2024
NHS Blood and Transplant
2020
Turgut Özal Tıp Merkezi
2010-2016
To analysis the appendiceal mucinous lesions according to World Health Organization (WHO) 2019 classification of tumors digestive system (non-neuroendocrine appendix vermiformis)Clinical and histopathological data 37 patients with histopathologically proven lesion from January 2010 May were evaluated retrospectively. Pathology slides re-evaluated by two pathologists WHO system.Totally (male:19 female: 18) aged 23 93 years analyzed. Majority (75.7 %) had underwent appendectomy due preliminary...
Methotrexate (Mtx) is an antineoplastic and immunosuppressive drug that may cause hepatotoxicity, whereas molsidomine (Mol) a vasodilating antioxidant agent. This study aimed to investigate the potential protective effects of Mol in Mtx-induced liver toxicity rats.Forty Wistar albino rats were equally divided into five groups: control, Mol, Mtx, Mol-Mtx, Mtx-Mol. Following treatment, animals sacrificed, tissue samples histopathologically evaluated using Roening grading Bcl-2 antibody...
This study was designed to investigate the protective effects of sitagliptin on renal damage induced by ischemia reperfusion (I/R) in rats. For this, rats were randomly divided into four groups (n = 8): (1) sham group, which only underwent right nephrectomy; (2) nephrectomy and left kidney (1 h) (24 group (I/R); (3) 5 mg/kg administrated per-oral once a day for two weeks; (4) weeks before I/R 8). Sitagliptin-treated that demonstrated significant decrease serum urea nitrogen creatinine also,...
Incidental appendectomy can be defined as the removal of a clinically normal appendix during another surgical procedure unrelated to appendicitis or other appendicular diseases.To compare demographic, biochemical, and histopathological features patients who underwent incidental standard appendectomy.The data 72 (Incidental App group) living donor hepatectomy at our Liver Transplant Center between June 2009 December 2016 were compared with 288 (Acute for presumed acute appendicitis. The group...
The aim of this study was to investigate the possible effects ivabradine against doxorubicin (DOX)-induced cardiotoxicity in rats using hemodynamic parameters (electrocardiogram, heart rate (HR), and blood pressure), biochemical markers oxidative stress, lactate dehydrogenase, aspartate transaminase, creatine kinase-MB, histopathological analyses both serum tissue specimens. A total 28 female were randomly assigned 4 groups: (a) control (n = 6 rats), (b) DOX group 7 (c) + ivabradine-treated...
This experimental study was designed to investigate both protective and therapeutic effects of aminoguanidine (AG), on radiotherapy (RT)-induced oxidative stress in kidney testis. Forty rats were divided into five groups equally as follows: (i) control, (ii) RT, (iii) AG, (iv) AG+RT (v) RT+AG group. Histopathological findings biochemical evaluations, including tissue malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), (GSH), total oxidant status...
Objective: The effects of electromagnetic radiation (EMR) produced by a third-generation (3G) mobile phone (MP) on rat brain tissues were investigated in terms magnetic resonance spectroscopy (MRS), biochemistry, and histopathological evaluations. Methods: rats randomly assigned to two groups: Group 1 is composed 3G-EMR-exposed ( n = 9) 2 the control group 9). first was subjected EMR for 20 days. not exposed EMR. Choline (Cho), creatinin (Cr), N-acetylaspartate (NAA) levels evaluated MRS....
Prostacyclin (PGI2) has been shown to inhibit the expression of pro-inflammatory and pro-fibrotic mediators in pulmonary fibrosis. In this study, we aimed test preventive effects intraperitoneally administered iloprost, a stable PGI2 analog, on bleomycin-induced fibrosis rats compare iloprost with methyl-prednisolone, traditional therapy.Rats were randomly allocated into four groups: 1. Saline alone (n=6); 2. Bleomycin+placebo (n=7); 3. Bleomycin+methyl-prednisolone 4. Bleomycin+iloprost...
Background. Cisplatin, an effective chemotherapeutic agent, is used for the treatment of several types cancers. However, cisplatin has some severe side effects such as nephrotoxicity. On other hand, molsidomine, a NO donor, anti-oxidative and vasodilator effects.Objectives. The aim this study was to estimate protective molsidomine on cisplatin-induced nephrotoxicity.Material Methods. Thirty-two rats were randomly divided into 4 groups follows: (1) control; (2) received single-dose...
Montelukast, a selective cysteinyl leukotriene D4-receptor antagonist, is used in the treatment of asthma. In rat model, our aim was to investigate effects montelukast, alone or combination with topical antibiotics, on local burn wound healing.Rats were randomly allocated four groups after development: Group 1; rats left secondary healing without treatment, 2; dose 10 mg/kg montelukast given by gastric gavage once day for days, 3; treated pomade (bacitracin neomycin sulphate), and 4; treat...
Cisplatin, an effective chemotherapeutic agent, is used for the treatment of several types cancers. However, cisplatin has some severe side effects such as nephrotoxicity. On other hand, molsidomine, a NO donor, anti-oxidative and vasodilator effects.The aim this study was to estimate protective molsidomine on cisplatin-induced nephrotoxicity.Thirty-two rats were randomly divided into 4 groups follows: (1) control; (2) received single-dose intraperitoneal (i.p.) injection 5 mg/kg cisplatin;...
A 59-year-old woman who had left nephrectomy because of renal cell carcinoma (RCC) 3 years ago referred with trismus and a mass on her temporomandibular joint. Computed tomography scan revealed an expanding lytic lesion the condyle mandible. Incisional biopsy was carried out. Histopathologic diagnosis metastatic clear variant RCC. Metastasis RCC to mandible has not been reported yet. In this study, we presented case metastasis
Synovial chondromatosis is a formation of multiple intrasynovial nodules resembling osteochondromas, resulting from proliferative changes in the synovial linings joints; as disorder progresses, increasingly withdraw areas for joint cavities. This relatively unusual case that can arise at unilateral large joints, such knee, hip, and elbow, with temporomandibular being rarest one them. Early recognition signs symptoms resultant accurate diagnosis, well proper surgical treatment, offers...
Abstract Actinomycosis is an uncommon, chronic, granulomatous disease that can be mistaken for a malignant tumor. Abdominopelvic actinomycosis constitutes about 20% of all cases and may mimic malignancy, tuberculosis, or other abdominopelvic inflammatory diseases. This condition more prevalent in women who use intrauterine device. We treated 44-year-old woman presented with vaginal discharge, right flank pain, dysuria, difficulty defecation. She had anorexia weight loss (8 kg) during the...
Objective: The aim of this study was to evaluate histopathological, functional and bone densitometry examinations the beneficial effects dexpanthenol (DEX) on nerve regeneration in a rat model peripheral crush injury.Methods: Thirty adult Sprague-Dawley rats were divided equally into three groups. A injury simulated all by clamping right sciatic for one minute. In group 1, day before surgical procedure, 500 mg/kg DEX administered via intraperitoneally (ip) initiated continued times week...
Background/Aims: Solitary rectal ulcer syndrome (SRUS) can be overlooked, diagnosed late, or misdiagnosed, particularly in childhood.This study reviewed the 13-year experience of authors' institution to increase clinicians' awareness SRUS presence symptoms.This paper reports endoscopic and histopathological findings children presenting with hematochezia.Methods: The clinical laboratory 22 patients biopsy-proven clinic between 2007 2020 were evaluated retrospectively.Results: mean age at...
Severe functional and anatomical defects can be detected after the peripheral nerve injury. Pharmacological approaches are preferred rather than surgical treatment in of injuries.The aim this study is to perform histopathological, bone densitometry examinations effects sildenafil on regeneration a rat model crush injury.Animal experiment.The included total thirty adult Sprague-Dawley rats that were divided into three groups ten each. In all rats, injury was created by clamping right sciatic...
Epistaxis is an important emergency that can sometimes be life threatening without effective intervention. Persistent and recurrent bleeding lead to aspiration, hypotension, hypoxia, or even severe mortal cardiovascular complications. Providing prompt hemostasis important, the hemostatic method used must easily locally applicable, efficient, inexpensive.The aim of this study was assess efficacy Ankaferd Blood Stopper (ABS) in experimental epistaxis model determine histopathologic alterations...
Teratomas are congenital germ cell tumors composed of elements from 1 or more the embryonic layers and contain tissues usually foreign to anatomic site origin. In head neck region, these lesions rare, 90% teratomas present during neonatal infantile periods. Besides, in neonates, it carries serious risk for respiratory distress as well feeding problems due oral cavity airway obstruction.Here, an unusual case intraoral teratoma involving orbit a newborn who underwent immediate surgical...