A5076103649- Saffron Plant Research Studies
- Bone Tissue Engineering Materials
- Circadian rhythm and melatonin
- Dental Implant Techniques and Outcomes
- Drug-Induced Hepatotoxicity and Protection
- Spaceflight effects on biology
- Periodontal Regeneration and Treatments
- Hemostasis and retained surgical items
- Biochemical Acid Research Studies
- Flavonoids in Medical Research
- Nigella sativa pharmacological applications
- Chemotherapy-induced organ toxicity mitigation
- Bone health and osteoporosis research
- Orthopaedic implants and arthroplasty
- Phytochemical and Pharmacological Studies
- Potato Plant Research
- Anesthesia and Neurotoxicity Research
- Birth, Development, and Health
- Neurological Disorders and Treatments
- Neuropeptides and Animal Physiology
- Olfactory and Sensory Function Studies
- Insect and Pesticide Research
- Dye analysis and toxicity
- Neuroscience of respiration and sleep
- Magnesium in Health and Disease
Inonu University
2015-2024
Harran University
2018-2024
Atatürk University
2020
Dicle University
2016
The University of Agriculture, Peshawar
2016
Malatya Devlet Hastanesi
2009
Stomatology Hospital
2007
Adli Tıp Kurumu
2003
University of Eastern Finland
1999
The present study was planned to investigate the protective effect of 10 % and 20 apricot-containing feed on carbon tetrachloride (CCl 4 )-induced hepatic steatosis damage. Adult male Wistar rats ( n 42) were divided into six groups seven each, as follows: control group; CCl +10 apricot +20 group. All fed with or for 5 months. injections applied at dose 1 mg/kg 3 d end In group, vacuolated hepatocytes necrosis seen, especially in centrilobular area. Hepatocytes showed an oedematous...
We hypothesized that the mitochondria of granulosa cells (GC) and/or oocytes might be abnormal in a mouse model fragile X premutation (FXPM).Mice heterozygous and homozygous for FXPM have increased death (atresia) large ovarian follicles, fewer corpora lutea with gene dosage effect manifesting decreased litter size(s). Furthermore, mice mitochondrial content, structurally mitochondria, reduced expression critical genes. Because this allele produces mutant Fragile mental retardation 1 (Fmr1)...
This study was planned to investigate the protective effect of l(+)-ascorbic acid (Vit C) on CCl(4)-induced hepatotoxicity and oxidative stress in liver Wistar rats (Rattus Norvegicus, strain Wistar). Twenty-four adult male were fed with standard rat chow diet for 10 days randomly divided into four groups six each as follows: (1) control, (2) CCl(4), (3) "CCl(4) + Vit C", (4) C groups. CCl(4) applied belonging C" subcutaneously at 1 mg kg(-1) dose 3 days. "Vit group intraperitoneally 300 All...
Abstract Adrenomedullin (AdM) was originally discovered as a vasorelaxant peptide. The antioxidative properties of AdM have been reported recently. Through its effect, adrenomedullin can protect organs from damage induced by stressors. Lead, commonly detected in air, soil, water and food, is major source oxidative stress. effect the liver rats exposed to lead investigated. Twenty‐four female Wistar were divided into four groups: control group (C), (AdM), (Pb) + (Pb AdM) group. In Pb‐treated...
Oxidative stress is one of the major causes methotrexate induced lung injury (MILI). Alpha-lipoic acid (ALA), which occurs naturally in human food, has antioxidative and anti-inflammatory activities. The aim this study was to research potential protective role ALA on MILI rats.Twenty rats were randomly subdivided into three groups: control (group I), (MTX) treated II), MTX+ALA III). Lung performed with a single dose MTX (20 mg/kg) groups 2 3. On sixth day, animals all sacrificed by...
To determine the antioxidant and anti-inflammatory effects of alfa lipoic acid (ALA) on liver injury induced by methotrexate (MTX) in rats.Thirty two rats were randomly assigned into four equal groups; control, ALA, MTX with ALA groups. Liver was performed a single dose (20 mg/kg) to groups 3 4. The administered intraperitonealy for five days 2 other received saline injection. At sixth day decapitated, blood tissue samples removed TNF-α, IL-1β, malondialdehyde, glutathione, myeloperoxidase...
The aim of this study was to compare the effects hydroxyapatite (HA), deproteinized bovine bone (DPB), human-derived allogenic (HALG), and calcium sulfate (CAP) graft biomaterials used with titanium barriers for augmentation treat peri-implant defects in rat calvarium treated by guided regeneration (GBR).Thirty-two female Sprague-Dawley rats were divided into four groups: DPB, HALG, HA, CAP.One barrier fixed each rat's after implants had been fixed.In total, 32 used.Ninety days surgical...
Cold exposure can induce a form of environmental stress. stress (CS) alters homeostasis, results in the creation reactive oxygen species and leads to alterations antioxidant defense system. The caffeic acid phenethyl ester (CAPE), an active component propolis, has capacity. We investigated effect CS on oxidative system possible protective CAPE rat liver tissue. Twenty-four female Wistar Albino rats were divided into four groups: Control, CAPE-treated, CS, CAPE-treated (CS + CAPE) group....
Thirty rats, with confirmed pregnancies by vaginal smear, were divided into five groups, each including six as the Control, Corn Oil, Vitamin E, Acrylamide, E + Acrylamide groups. The births monitored on 21st day to select male and selected rats decapitated at end of 8th week. Oxidant-antioxidant parameters, serum hormone levels histopathological examinations performed testis tissues rats. It was found that acrylamide (AA) negatively affected (Total Testosterone, Progesterone, FSH, LH,...
It is generally agreed that one of the major contributors to skin aging reactive oxygen species. As organisms reach advanced age, free radical generation increases and activity tissue antioxidant enzyme system decreases. Melatonin an scavenger. The present study was first aimed determine morphometric biochemical changes caused by long-term pinealectomy in order investigate role melatonin as architecture. Secondly, effect exogenous administration on these determined. Rats were pinealectomized...
The aim of the present study was to evaluate effect local melatonin application during surgery on bone implant connection (BIC) in rabbit tibiae. Six 0.8- 1-year-old male New Zealand rabbits were divided into 3 groups: (1) a control group (CG) which not treated with additive materials and only integration executed; (2) dose 1 (MLT D-1) 1.2 mg locally before placement rabbits' tibiae; (3) 2 D-2) Four weeks after procedure, euthanized; their tibiae dissected from muscles soft tissues, fixed...
Objectives: The objective of this study is to investigate possible damages kidney tissues pregnant rats and their fetuses exposed acrylamide during pregnancy protective effects vitamin E against these damages. Material methods: Rats were randomly assigned five groups control, corn oil, E, acrylamide, + six in each. Mother fetal examined for malondialdehyde (MDA), reductase glutathione (GSH), superoxide dismutase (SOD), catalase (CAT), total antioxidant status (TAS), oxidant (TOS), urea,...
Background.Periodontitis, a chronic inflammatory disease affecting the supporting tissues around teeth, causes significant and oxidative changes in cardiac tissue.Crocin is active constituent of Crocus sativus (saffron) which has antioxidant properties protective against cardiovascular disturbances.Objectives.The present study aimed to investigate effects crocin on periodontitis-induced oxidative/inflammatory degeneration rats vivo. Materials methods.Thirty female Sprague Dawley were...
The present study aimed to investigate the effects of periodontitis on kidneys and protective role crocin in periodontitis-induced kidney damage.Ethics committee approval was obtained 30 Wistar rats were randomly divided into 3 groups 10 rats: Control (C), Periodontitis (P), + Crocin (P Cr). After treatments, rat tissues incised under anesthesia blood samples collected. Biochemical histopathological analyses conducted samples.Malondialdehyde (MDA), total oxidant status (TOS), oxidative...