A5049996565- European and International Law Studies
- Bacteriophages and microbial interactions
- EU Law and Policy Analysis
- Taxation and Legal Issues
- Probiotics and Fermented Foods
- Legal case studies and regulations
- World Trade Organization Law
- Genomics and Phylogenetic Studies
- Merger and Competition Analysis
- International Arbitration and Investment Law
- European Criminal Justice and Data Protection
- SARS-CoV-2 and COVID-19 Research
- Infectious Aortic and Vascular Conditions
- Conflict of Laws and Jurisdiction
- Bacterial Genetics and Biotechnology
- Streptococcal Infections and Treatments
- European and International Contract Law
- Corporate Governance and Law
- Central Venous Catheters and Hemodialysis
- Cystic Fibrosis Research Advances
- Vibrio bacteria research studies
- Infective Endocarditis Diagnosis and Management
- Infections and bacterial resistance
- Infection Control and Ventilation
- Discrimination and Equality Law
Royal Free London NHS Foundation Trust
2025
University College London
2024
The Royal Free Hospital
2024
University Hospital Galway
2020-2022
St. Vincent's University Hospital
2020-2022
University College Dublin
1970-2021
Mercy University Hospital
2019
Sutherland Hospital
2017
London School of Economics and Political Science
2012
University of Tulsa
2008
Abstract Background During the first wave of coronavirus disease 2019 (COVID-19) pandemic, outbreaks severe acute respiratory syndrome 2 (SARS-CoV-2) in healthcare institutions posed a significant problem. Due to limited evidence, guidance on appropriate infection prevention and control (IPC) measures such as wearing face masks varied. Here, we applied whole virus genome sequencing (WvGS) analyze transmission routes SARS-CoV-2 hospital-acquired (HA) COVID-19. Methods An investigation was...
Background & AimsEnteropathy and small-intestinal ulcers are common adverse effects of nonsteroidal anti-inflammatory drugs such as acetylsalicylic acid (ASA). Safe, cytoprotective strategies needed to reduce this risk. Specific bifidobacteria might have activities, but little is known about these in humans. We used serial video capsule endoscopy (VCE) assess the efficacy a specific Bifidobacterium strain healthy volunteers exposed ASA.MethodsWe performed single-site, double-blind,...
Abstract Background The National Bowel Screening Program (Bowelscreen), a nationwide initiative program, aims to provide direct access those aged 55-74 (currently 59-69) for colonoscopy assessment deemed high risk colorectal cancer via positive faecal immunochemical test (FIT). Inflammatory Disease (IBD) follows bimodal distribution of onset with European studies reporting 10-15% diagnosis after age 60. Limited published research exists on IBD incidence in Ireland FIT-based population...
Objectives: To measure SARS-CoV-2 antibody seroprevalence within a cohort of adults living with HIV and correlate demographics response rates to SARS CoV-2 vaccination. Design: Initial vaccine trials for did not examine efficacy in people HIV. We undertook the SCAPE-HIV study from April 2021 November 2022 focus on this population guide future scheduling. Methods: Participants completed retrospective questionnaire. Nucleocapsid spike antibodies (anti-N anti-S) were tested. Demographic factors...
pCI528 is a 46 kb plasmid, originally isolated from Lactococcus lactis subsp. cremoris UC503, which causes decrease in bacteriophage adsorption lactococcal strains. Cell surface characteristics of two pCI528-containing strains, L. UC503 and UC505, were compared with those their isogenic pCI528-cured derivatives, UC563 MG1363, respectively. Following centrifugation, strains containing produced loose fluffy pellet. The presence also caused ‘hard’ colony morphology on agar media. pellet effect...
Universal stress proteins (USPs) are ubiquitously expressed in bacteria, archaea, and eukaryotes play a lead role adaptation to environmental conditions. They enable of bacterial pathogens the conditions encountered human niche, including hypoxia, oxidative stress, osmotic nutrient deficiency, or acid thereby facilitating colonization. We previously reported that all six USP encoded within low-oxygen activated (lxa) locus Burkholderia cenocepacia showed increased abundance during chronic...
Purpose This paper aims to understand the emergence, operation and evolution of judge-centred models for enforcement competition law in Ireland Hong Kong SAR. The public model chimes with Irish regime where competence adjudicate on violations impose sanctions is intentionally reserved exclusively judges. design choice renders regimes both similar each other atypical global stage, many jurisdictions an administrative agency investigates suspected infringements, makes determinations...
A 10-kb HindIII fragment of pCI528 cloned into the nonconjugative shuttle vector pCI3340 could be transferred by conjugative mobilization from Lactococcus lactis subsp. MG1363, whereas other fragments or alone were nonmobilizable. Subcloning this region identified a 4.4-kb BglII-EcoRI which contained all DNA essential for transfer. Sequence analysis 2-kb within 4.4 kb-segment revealed rich in inverted repeats and two potential overlapping open reading frames, one demonstrated homology to...
The replication region of the phage resistance plasmid pCI528 from Lactococcus lactis subsp. cremoris UC503 was localised to within a 10-kb HindIII restriction fragment. A 6.3-kb BglII-HindIII subclone this fragment, cloned into probe vector, allowed in but not Bacillus or Lactobacillus. Sequence analysis revealed an ORF 1152 bp preceded by putative ori containing 22-bp sequence tandemly repeated three and three-quarter times, second smaller direct repeat two inverted repeats. Extensive...
This report describes recurrent A. xylosoxidans bloodstream and PICC (peripherally-inserted central catheter) line infection in an immunocompromised patient.A 64-year-old female with acute promyelocytic leukaemia presented during a non-neutropenic febrile episode, was isolated from multiple peripheral blood cultures, the tip of on removal. The patient treated meropenem new inserted after sterile cultures. Six weeks later, she represented cultures line. She piperacillin-tazobactam removed....
This article argues for the recognition of some professionals in employment as ‘undertakings’ on grounds that they are ‘false employed’—a term inspired by Dutch Orchestra which regarded self-employed musicians self-employed’ who lost their status ‘undertaking’. It teases out potential parameters this category drawing labour law research and suggests it extends beyond liberal to include employed in, example, financial services IT. Adopting approach would secure applicability Art 101TFEU (and,...
The common law restraint of trade doctrine continues to provide valuable protection in a variety business contexts. This paper analyses an incompatibility problem that has arisen between and EU competition rules (in particular Art 101 Treaty on the Functioning [TFEU]) as implemented by Regulation 1/2003, which, amongst other matters, delineates interface national law. According High Court, once court applied TFEU, 3 prevents from reaching contrary finding under doctrine. Thus, cannot find...
Abstract Background and Aims Human Cytomegalovirus (CMV) can cause significant morbidity in transplant recipients. Primary CMV infection seronegative recipients (R−) reactivation of seropositive (R+) post-transplant lead to end organ disease (EOD). At Royal Free Hospital (RFH), London, United Kingdom, EOD is prevented through pre-emptive therapy (PET), which utilises quantitative real-time PCR (qPCR) whole blood monitor all patients guide therapeutic interventions (1). PET started D+R−...
Summary Universal stress proteins (USPs) are ubiquitously expressed in bacteria, plants and eukaryotes play a lead role adaptation to environmental conditions. In Gram negative bacteria they enable adaption of bacterial pathogens the conditions encountered human niche, including hypoxia, oxidative stress, osmotic nutrient deficiency or acid thereby facilitating colonisation. We previously reported that all six USP encoded within low-oxygen responsive locus Burkholderia cenocepacia showed...
Lactococcus lactis subsp. 952, used as a component of cheese starter culture, was found to be closely related the 712/ML3/C2 group strains. Plasmid profiles four isolates were very similar and factory phages isolated against strain 952 could produce plaques on all other strains at same titres. Treatment with mitomycin C failed induce phage from although homology observed between φT712 chromosome 952. Pulse field gel electrophoresis revealed only minor differences in their genomic DNA. The...
Abstract Blood cultures should be performed in non‐specifically unwell older adults following nonspecific presentations. Prompt diagnosis and commencement of targeted antimicrobial therapy are essential patients with A. defectiva IE.
Journal Article The New Irish Competition and Consumer Protection Commission: Is This ‘Powerful Watchdog with Real Teeth’ Powerful Enough under EU law? Get access Mary Catherine Lucey *Barrister-at-law, UCD Sutherland School of Law. mary.catherine.lucey@ucd.ie Search for other works by this author on: Oxford Academic Google Scholar European Law & Practice, Volume 6, Issue 3, March 2015, Pages 185–191, https://doi.org/10.1093/jeclap/lpu103 Published: 19 November 2014