A5040389501- Photoacoustic and Ultrasonic Imaging
- Advanced Fiber Laser Technologies
- Advanced Fiber Optic Sensors
- Solid State Laser Technologies
- Thermography and Photoacoustic Techniques
- Laser Design and Applications
- Photonic Crystal and Fiber Optics
- Optical Imaging and Spectroscopy Techniques
- Microwave Engineering and Waveguides
- Photonic and Optical Devices
- Antenna Design and Analysis
- Optical Coherence Tomography Applications
- Optical Network Technologies
- Advanced Antenna and Metasurface Technologies
- Nanoplatforms for cancer theranostics
- Photodynamic Therapy Research Studies
- Advanced Photonic Communication Systems
- Spectroscopy Techniques in Biomedical and Chemical Research
- Laser-Matter Interactions and Applications
- Mechanical and Optical Resonators
- Plasmonic and Surface Plasmon Research
- Laser Material Processing Techniques
- Ultrasound Imaging and Elastography
- Metamaterials and Metasurfaces Applications
- Wireless Body Area Networks
Changchun University of Science and Technology
2020-2025
Ministry of Agriculture and Rural Affairs
2025
Sichuan Agricultural University
2025
Jinan University
2015-2024
University of Electronic Science and Technology of China
2011-2023
Hubei University
2023
Fujian Medical University
2022-2023
First Affiliated Hospital of Jinan University
2022
Jinan University
2022
City University of Hong Kong
2022
A new level of anisotropic plasmonic laser printing for aluminum multifunctional metasurfaces.
Photoacoustic endoscopy shows promise in the detection of gastrointestinal cancer, inflammation, and other lesions. High-resolution endoscopic imaging hemodynamic response necessitates a small-sized, high-sensitivity ultrasound sensor. Here, we utilize laser sensor to develop miniaturized, optical-resolution photoacoustic endoscope. The can boost acoustic by gain factor ωo/Ω (the frequency ratio signal light measured ultrasound) measuring acoustically induced optical phase change. As result,...
Abstract Traumatic brain injury (TBI), recognized as the world's most serious public health problem, currently lacks effective treatment options. The development of patch has great clinical significance whether it is used a skull implant material or TBI repair. In response to this critical challenge, novel 3D‐printed bi‐layer cranial‐brain (SMB6) with dual functionality, addressing both repair and regeneration, developed. first layer, incorporation high concentrations mesoporous bioactive...
Abstract We report the development of a head-mounted photoacoustic fiberscope for cerebral imaging in freely behaving mouse. The 4.5-gram probe has 9-µm lateral resolution and 0.2-Hz frame rate over 1.2-mm wide area. can continuously monitor oxygenation hemodynamic responses at single-vessel resolution, showing significantly different cerebrovascular to external stimuli under anesthesia moving state. For example, when subjected high-concentration CO 2 respiration, enhanced compensate...
We design and demonstrate a miniature all-fiber Fabry-Perot (F-P) interferometric sensor based on hollow-core photonic bandgap fiber where the strain is gauged by measuring spectrum shift of reflected optical signal. The F-P cavity in order millimeters fabricated simple techniques cleaving fusion splicing. sensitivity 1.55 pm/muepsiv at wavelength 1550 nm contrast intensity reaches 4-6 dB. Temperature bend insensitivity excellent repeatability make it convenient for wide range applications.
Fast functional photoacoustic microscopy requires multi-wavelength pulsed laser sources with high pulse repetition rates, short wavelength switching time, and sufficient energies. Here, we report the development of a stimulated-Raman-scattering-based source for fast imaging. The new is pumped 532 nm 1 MHz laser. beam split into two: one pumps 5 m optical fiber to excite 558 via stimulated Raman scattering; other goes through 50 delay by 220 ns. two beams are combined coupled an excitation....
Abstract Photoacoustic imaging, especially for intravascular and endoscopic applications, requires ultrasound probes with miniature size high sensitivity. In this paper, we present a new photoacoustic sensor based on small-sized fiber laser. Incident waves exert pressures the optical laser induce harmonic vibrations of fiber, which is detected by frequency shift beating signal between two orthogonal polarization modes in This presents noise-equivalent pressure 40 Pa over 50-MHz bandwidth. We...
Highly sensitive detection of molecular tumor markers is essential for biomarker-based cancer diagnostics. In this work, we showcase the implementation fiber light-coupled optofluidic waveguide (FLOW) immunosensor p53 protein, a typical marker. The FLOW consists liquid-core capillary and an accompanying optical fiber, which allows evanescent interaction between light microfluidic sample. Molecular binding at internal surface induces response in wavelength shift transmission spectrum fiber....
We developed a novel theoretical model of dual-wavelength laser amplifier based on intra-cavity pumping technology. In this model, we derived analytical expressions for the output power amplifier. Simulations were conducted to explore characteristics The effects crystal length and beam radius laser's performance investigated, providing solid foundation further research.
We report the implementation of an in-fiber optical switch by means filling a fluid into air holes photonic crystal fiber with Bragg grating. Such can turn on/off light transmission extinction ratio up to 33 dB within narrow wavelength range (Bragg wavelength) via small temperature adjustment ±5°C. The switching function is based on temperature-dependent coupling between fundamental core mode and rod modes in fluid-filled resulting from thermo-optic effect filled fluid.
A localized surface plasmon resonance enhancement at near infrared wavelengths has been achieved by constructing raspberry-like meso-SiO<sub>2</sub> nanospheres.
Photoacoustic imaging (PAI) is a noninvasive biomedical technology capable of multiscale biological samples from organs down to cells. Multiscale PAI requires different ultrasound transducers that are flat or focused because the current widely-used piezoelectric rigid and lack flexibility tune their spatial responses. Inspired by rapidly-developing flexible photonics, we exploited inherent low-loss features optical fibers develop fiber-laser sensor (FUS) for PAI. By simply bending fiber...
A dual-core photonic bandgap fiber (PBGF) is demonstrated by infusing a high-index liquid into air-silica crystal (PCF). Extremal couplings have been experimentally observed. The temperature tunable characteristics of the PBGF's guiding and coupling are numerically investigated. When we rise temperature, PBGFs' bandgaps changed: compression bandwidth, blue-shift depression band. Especially, because tunability infusion liquid's index. We find that increases length which results in resonant...
Optical-resolution photoacoustic microscopy (OR-PAM) images biological tissue with sub-cellular resolution and optical absorption contrast. OR-PAM is limited by the tradeoff among imaging speed, field of view, sensitivity. In this work, we present an technique based on unfocused side-looking fiber optic ultrasound (FOUS) sensor, which achieves high large good sensitivity for in vivo imaging. The FOUS sensor developed a dual-polarized laser read out real-time frequency demodulation. Via...
We have developed highly sensitive photonic ultrasound hydrophones based on polymer-packaged dual-polarization-mode fiber lasers. The incident wave is scattered by the polymer cylinder due to difference in elastic property. can drive harmonic vibration of and result optical response terms beat-frequency variation laser output. Experimental results exhibit a broadband at frequencies below 1 MHz. individual modes are excited waves with different efficiencies, yielding frequency-dependent...
Photothermal therapy (PTT) has received constant attention as an efficient cancer method due to locally selective treatment, which is not affected by the tumor microenvironment. In this study, a novel 880 nm near-infrared (NIR) laser-triggered photothermal agent (PTA), 3TT-IC-4Cl, was used for PTT of in deep tissue. Folic acid (FA) conjugated amphiphilic block copolymer (folic acid-polyethylene glycol-poly (β-benzyl-L-aspartate)10, FA-PEG-PBLA10) employed encapsulate 3TT-IC-4Cl...