A5089624899- MicroRNA in disease regulation
- Extracellular vesicles in disease
- COVID-19 Clinical Research Studies
- Circular RNAs in diseases
- Vitamin C and Antioxidants Research
- SARS-CoV-2 and COVID-19 Research
- Adenosine and Purinergic Signaling
- Vitamin D Research Studies
- Pharmacological Effects and Toxicity Studies
- Advanced biosensing and bioanalysis techniques
- Sexual function and dysfunction studies
Universidade Estadual de Campinas (UNICAMP)
2020-2024
Hospital de Clínicas da Unicamp
2021
Coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It known that host microRNAs (miRNAs) can be modulated to favor viral infection or protect the host. Herein, we report preliminary results of study aiming at identifying differentially expressed plasmatic miRNAs in Brazilian patients with COVID-19.miRNAs were extracted from plasma eight COVID-19 (four mild and four severe/critical COVID-19) healthy controls....
Abstract Coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome 2 (SARS-CoV-2). Recent research has demonstrated how epigenetic mechanisms regulate the host–virus interactions in COVID-19. It also shown that microRNAs (miRNAs) are one of three fundamental regulation gene expression and play an important role viral infections. A pilot study published our group identified, through next-generation sequencing (NGS), miR-4433b-5p, miR-320b, miR-16–2-3p differentially...
When using the reverse-transcription quantitative polymerase chain reaction (RT-qPCR) technique for assessment of microRNA (miRNA) expression, normalizing data a stable endogenous gene is essential; however, no universally adequate reference exists. Therefore, in this study, we aimed to determine, via RNA-Seq technique, most normalizer expression plasma miRNAs patients with coronavirus disease 2019 (COVID-19). Two massive sequencing procedures were performed (a) identify differentially...
Abstract Background: Coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It known that host microRNAs (miRNAs) can be modulated to favor viral infection or protect the host. Objective: The aim of this study was identify differentially expressed circulating miRNAs in Brazilian patients with COVID-19 as potential biomarkers for diagnosis and severity. Methods: were extracted from blood plasma eight (four...