A5013978955- Multiple Sclerosis Research Studies
- Migraine and Headache Studies
- Autoimmune and Inflammatory Disorders Research
- Sympathectomy and Hyperhidrosis Treatments
- Neuroscience of respiration and sleep
- Neurological disorders and treatments
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Brucella: diagnosis, epidemiology, treatment
- Dermatological and Skeletal Disorders
- Sphingolipid Metabolism and Signaling
- Ophthalmology and Eye Disorders
- Ion channel regulation and function
- Galectins and Cancer Biology
- Neurological Complications and Syndromes
- Cerebral Palsy and Movement Disorders
- Cancer Treatment and Pharmacology
- Neuropeptides and Animal Physiology
- Respiratory viral infections research
- Peripheral Neuropathies and Disorders
- Dupuytren's Contracture and Treatments
- Burkholderia infections and melioidosis
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Effects of Vibration on Health
- Glaucoma and retinal disorders
- Epilepsy research and treatment
Gaziantep University
2014-2024
Kilis 7 Aralık University
2023
Sanko University
2023
Mersin Üniversitesi
2004
This study aimed to detect metastases in patients with stage III or IV cutaneous melanoma by 18 F-fluorodeoxyglucose positron emission tomography combined computed (FDG-PET/CT). Thirty-nine clinically evident underwent whole-body FDG-PET/CT scans for metastatic disease and these results were compared those of biopsy. Scans 38 the evaluated; one patient's scan could not be evaluated. There 11 true-positive, two false-positive, 24 true-negative false-negative detection metastases, sensitivity...
Elevated levels of macrophage migration inhibitory factor (MIF) have been observed in the cerebrospinal fluid patients with multiple sclerosis. This study was designed to determine if MIF gene polymorphisms are associated sclerosis and disease severity. In total, 120 relapsing-remitting control subjects were enrolled study. There a statistically significant increase −173 CC genotype compared subjects. The −794 6/7 had significantly lower progression index 6/6. Patients age onset those CG GG...
Objectives: Improving the proficiency of oligodendrocytes in their ability to repair myelin damage is one major goals multiple sclerosis treatment. Insulin-like growth factor-1 (IGF-1) several polypeptides that are considered have potential benefits sense. In present study, we aimed determine serum levels IGF-1 and insulin-like factor binding protein-3 (IGFBP-3), thyroid stimulating hormone (TSH) (GH) among treated non-treated patients with Relapsing-Remitting Multiple Sclerosis (RRMS) a...
The purpose of this study was to investigate the possible association between childhood epilepsy and KCNJ10 gene polymorphisms (rs61822012 rs2486253). A total 200 epileptic cases healthy controls enrolled study. Genomic DNAs from patients control were analyzed by polymerase chain reaction (PCR) restriction fragment length polymorphism methods. There significant associations G/T genotype rs2486253 in idiopathic generalized group (P = .037) subjects with tonic-clonic seizures .0015). T allele...
Dysregulation in the expression of pro- and anti-inflammatory cytokines is one milestones multiple sclerosis (MS) development progression. Tumour necrosis factor (TNF-alpha), a proinflammatory cytokine believed to play an important role MS pathogenesis. The objective this study investigate association between TNF-alpha promoter region (TNF-alpha-238, -308 -857) susceptibility clinical course disease. Eighty-six relapsing remitting patients 150 sex-, age- ethnic-matched controls were enrolled...
A migraine attack is a spectacularly complex brain event that can produce wide array of neurological and systemic symptoms. The molecular mechanisms genetics have not yet been clarified. objective this study was to analyze the genotype distributions allele frequencies for C276T polymorphism neuronal nitric oxide synthase (nNOS) gene among patients with migraine. diagnosis made clinically based on questionnaires. One hundred twenty were genotyped nNOS compared 185 age-matched healthy...
We report a rare case of simultaneous cranial subarachnoid and spinal subdural hematoma (SDH) in 42-year-old man who was on Warfarin therapy after cardiac bypass surgery.Computed tomography at presentation revealed hemorrhage, Magnetic Resonance Imaging (MRI) showed SDH extending from the T6 to L5 segments.He had paraparesis due cord compression.The patient managed conservatively his poor general condition infused with intravenous steroid therapy, but he experienced sudden arrest 5 hours...
In this study, the relationship between plasma levels of melatonin and intercellular adhesion molecule-1 (ICAM-1), which plays role in several interactions including inflammatory immune responses, early neurocognitive functions associated with ischaemia-reperfusion injury during open heart surgery is examined.Forty patients who were to undergo elective coronary artery bypass grafting (CABG) divided into two groups, those underwent their operations at 8 AM (group I; n = 20) 1 PM II; 20)....
Background/aim: During multiple sclerosis (MS) treatment different modes of action such as lateral (interferon beta to glatiramer acetate or interferon beta) vertical beta/glatiramer fingolimod) drug switch can be performed. This study aims investigate the clinical effectiveness switching from first-line injectable disease modifying treatments (iDMTs) fingolimod (FNG) compared between iDMTs. Materials and methods: is a multicenter, observational retrospective patients with...
Background: Migraine has a complex etiology determined by genetic and environmental factors, but the molecular mechanisms genetics of this disease have not yet been fully clarified. Aim: This case/control study was designed to analyze genotype distributions allele frequencies for Rho-kinase 2 (ROCK2) gene Thr431Asn polymorphism among migraine patients. Materials Methods: A total 155 patients healthy age sex matched controls were included in study. Genomic deoxyribonucleic acid from analyzed...
Meningitis is the most common central nervous system complication of mumps virus, whereas encephalitis, cranial nerve palsies, poliradiculoneuritis are less and myelitis caused by virus very rare [Nussinovitch et al., Acta Pediatrica (1992) 81, 183]. Lesions in young age as a result severe acute transverse [shown on magnetic resonance imaging (MRI) procedure] often has viral cause. The case male afflicted meningoencephalomyelitis because discussed.
Background and Objectives: This study is designed to understand the pathophysiology of one most serious health problems, chronic tension-type headache (CTTH). Two polymorphic sites in serotonin transporter protein gene attracted much interest. These are: variable number tandem repeats (VNTR) 5'-flanking promoter region (5-HTTLPR). Materials Methods: VNTR 5-HTTLPR polymorphisms were investigated 126 CTTH patients 138 healthy control subjects. The being treated with amitripytyline or...
Neuroleptic malignant syndrome (NMS) is characterised by the impairment of consciousness, high fever, rigidity and autonomic instability.Although originally described in patients taking neuroleptic drugs, this may also occur with Parkinson's disease (PD) during withdrawal or reduction levodopa therapy other dopaminergic drug called (MS) neuroleptic-like syndrome. 1,2Dehydration, antiparkinsonian withdrawal, infections hot weather are considered to trigger syndrome.Diagnostic criteria were...
This study was conducted in order to examine the effect of acupressure applied patients with multiple sclerosis on fatigue. The meeting inclusion criteria were assigned intervention (n = 30) and control groups. data collected using a questionnaire Fatigue Severity Scale. During study, group received its routine treatment; other hand, treatment also certified researcher, receiving training, by points Li4, ST36 SP6 3 times week for total 4 weeks. postacupressure fatigue mean score 5.2 ± 0.7...